Review
Infectious Diseases
Sabrina Lunara Santos Pavelquesi, Ana Carolina Almeida de Oliveira Ferreira, Angeislenie Ricelle Magalhaes Rodrigues, Calliandra Maria de Souza Silva, Daniela Castilho Orsi, Izabel Cristina Rodrigues da Silva
Summary: The study revealed high resistance rates of Salmonella to tetracyclines and sulfonamides, with poultry and pork being the most frequent samples used to isolate Salmonella. The most frequently detected tetracycline resistance genes in Salmonella were tetA and tetB, while sul1 was the most common sulfonamide resistance gene. These genes are associated with plasmids, transposons, or both, and have potential for transfer to other bacteria, environments, animals, and humans.
Article
Biotechnology & Applied Microbiology
Rupert Bassitta, Annika Nottensteiner, Johann Bauer, Reinhard K. Straubinger, Christina S. Hoelzel
Summary: This study quantified the absolute concentrations and relative abundances of antimicrobial resistance (AMR) genes in manure from organic and conventional farms. The results showed that the relative abundances of AMR genes were higher in conventional farms compared to organic farms. The use of antibiotics was linked to the relative abundance of AMR genes. However, the absolute concentrations of AMR genes were comparable between fertilizers from organic and conventional farms.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Environmental Sciences
Navneet Kumar, Uijin Jung, Bomseumin Jung, Jinsub Park, Mu. Naushad
Summary: In this study, a zinc hydroxystannate/zinc-tin oxide (ZHS/ZTO) heterostructure was synthesized and showed excellent photocatalytic degradation efficiency for methyl orange and tetracycline. The dominant role of OH radicals was confirmed in the photocatalytic removal process.
ENVIRONMENTAL POLLUTION
(2023)
Article
Multidisciplinary Sciences
Concepcion Sanchez-Cid, Timothy M. Ghaly, Michael R. Gillings, Timothy M. Vogel
Summary: Antibiotics at sub-inhibitory concentrations in the environment can still exert selective pressure on bacteria, leading to the selection and dissemination of antibiotic resistance. This study found that gentamicin at sub-inhibitory concentrations promoted the integration and selection of gentamicin resistance genes in class 1 integrons after just one day of exposure, potentially increasing their dissemination in the environment. These findings highlight the effects of antibiotics at sub-inhibitory concentrations and raise concerns about antibiotics as emerging pollutants.
SCIENTIFIC REPORTS
(2023)
Article
Veterinary Sciences
Shamim Sarkar, Marcy J. Souza, Tomas Martin-Jimenez, Mohamed A. Abouelkhair, Stephen A. Kania, Chika C. Okafor
Summary: The study measured antibiotic residues in antibiotic-free products sold at farmers' markets in East Tennessee. It found that all tested food products contained varying levels of antibiotic residues, but the median concentrations were below the maximum residue levels set in the U.S. for beef and eggs, indicating that these products are considered safe for consumption. However, no residue limit has been set for honey products, and further research is needed to determine the source of the residues in these foods.
VETERINARY SCIENCES
(2023)
Article
Green & Sustainable Science & Technology
Yafei Wang, Chenhao Wang, Shen Yan, Yingchun Li, Chen Cai, Huiling Liu, Peng Ren, Mengmeng Wang, Shaoping Kuang
Summary: In this study, nitrogen-doped biochar was used as an activator in a persulfate oxidation system to effectively degrade tetracycline, inactivate antibiotic resistant bacteria, and remove antibiotic resistant genes. The reactive sites for persulfate activation were found to be defects and edge pyridinic nitrogen generated during the nitrogen doping process. Singlet oxygen was the major mechanism for persulfate activation, while sulfate and hydroxyl radicals played minor roles. Tetracycline was degraded through hydroxylation, demethylation, and decarboxylation, and the NLBH/PDS system efficiently inactivated antibiotic resistant bacteria and reduced intracellular antibiotic resistant genes. This study highlights a promising alternative technique for the removal of antibiotics, antibiotic resistant bacteria, and intracellular antibiotic resistant genes in future advanced wastewater treatment systems.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Chemistry, Multidisciplinary
Li Zhao, Lalitkumar K. Vora, Stephen A. Kelly, Linlin Li, Eneko Larraneta, Helen O. McCarthy, Ryan F. Donnelly
Summary: Antibiotic resistance is a serious health problem and is expected to worsen in the future. Researchers have developed a hydrogel-forming microarray patch system that can deliver antibiotics in a sustained manner.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Engineering, Environmental
Jianhong Shi, Baoyi Lv, Binghan Wang, Bing Xie
Summary: Microplastic (MP) biofilms in landfill environment are hotspots of antibiotic resistance genes (ARGs), which are influenced by heavy metals and metallic nanoparticles (NPs) known as selective agents of ARGs. This study comparatively analyzed the effects of zinc oxide (ZnO) NPs and zinc ion (Zn2+) pressures on ARG abundances in MP biofilms and corresponding leachate. The presence of ZnO NPs and Zn2+ enhanced the enrichment of ARGs in MP biofilms, with ZnO NPs having a more pronounced effect. ZnO NPs and Zn2+ mainly decreased the abundances of ARGs in leachate.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Infectious Diseases
Diana Dias, Andreia Cruz, Carlos Fonseca, Sonia Mendo, Tania S. Caetano
Summary: In recent years, the interaction between wildlife and humans has been increasing due to human activities. It is important to understand the impact of these interactions on the health of wild animals and the potential risks of zoonotic diseases. This study used metabarcoding to analyze the fecal microbiota of red deer and identified several potential human and veterinary pathogens. The study also found the occurrence of antibiotic resistance genes, some of which are considered future threats to human health.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Environmental Sciences
Zeyou Chen, Lichun Yin, Wei Zhang, Anping Peng, J. Brett Sallach, Yi Luo, Hui Li
Summary: Soil salinity can affect the bioavailability of antibiotics to bacteria, with high salinity potentially increasing the selection pressure exerted by antibiotics on bacteria.
Article
Biochemistry & Molecular Biology
Ziyao Zhou, Ting Zhang, Yixin Chen, Xiaoxiao Zhou, Yalin Zhong, Haifeng Liu, Zhijun Zhong, Yanchun Hu, Fei Liao, Xianxiang Wang, Guangneng Peng
Summary: In this study, a strain of antibiotic-resistant Streptococcus agalactiae was isolated and analyzed for resistance and virulence genes. The results showed that zinc oxide quantum dots had a good antibacterial effect on this strain by reducing bacterial growth and decreasing the expression of virulence genes.
Article
Microbiology
V. J. Timms, K. A. Hassan, L. A. Pearson, B. A. Neilan
Summary: Antimicrobial resistance (AMR) is a major global health threat, with predictions of 10 million deaths annually by 2050. Cyanobacteria have been found to be a potential reservoir for AMR genes, with these genes found in diverse terrestrial and aquatic habitats.
ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jose A. Rodrigues, Wonhee Cha, Rebekah E. Mosci, Sanjana Mukherjee, Duane W. Newton, Paul Lephart, Hossein Salimnia, Walid Khalife, James T. Rudrik, Shannon D. Manning
Summary: In a four-year active surveillance study at four metropolitan hospitals in Michigan, an increasing trend in Campylobacter jejuni infections was observed. Analysis of 214 C. jejuni isolates revealed widespread antibiotic resistance, with differences in infection rates by hospital type and patient characteristics associated with disease severity.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Engineering, Environmental
Ran Duan, Shuanglong Ma, Shengjun Xu, Beibei Wang, Mengfei He, Guangxin Li, Haichao Fu, Peng Zhao
Summary: Tetracycline has been detected in various environments, leading to the development of resistance in bacterial populations. This study fabricated soybean straw biochars (SSBs) at different pyrolysis temperatures and used them as activators for the degradation of tetracycline and disinfection of tetracycline-resistant Escherichia coli. The results showed that the purification effect of SSBs depended on the pyrolysis temperature, with SSB1000/PS system exhibiting superior degradation and disinfection capabilities. The purification mechanisms of tetracycline and Escherichia coli were found to be different, with tetracycline degradation mainly relying on surface-bound radicals and bactericidal activity attributed to free SO4 center dot- in bulk solutions. The catalytic performance of SSB1000 was attributed to its unique characteristics, such as large mesopore volumes, high C=O content, low interfacial charge transfer resistance, and strong electron donating capacity.
Article
Engineering, Environmental
Mengmeng Wang, Yafei Wang, Yingchun Li, Chenhao Wang, Shaoping Kuang, Peng Ren, Binghan Xie
Summary: In order to reduce the negative impact of antibiotics and antibiotic resistance genes (ARGs) on the environment, this study used iron-loaded biochar (Fe-LBH) as an activator in a persulfate (PDS) oxidation system to degrade tetracycline (TC), inactivate antibiotic resistant bacteria (ARB), and remove ARGs. The Fe-LBH-PDS system showed efficient removal of TC (more than 85%) within 30 minutes, higher than the pristine biochar-PDS system (15.5%). In addition, it was found that Fe (II) and oxygen functional groups played important roles in the PDS activation process.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biotechnology & Applied Microbiology
F. Spitzer, S. Speiser, W. Vahjen, J. Zentek
Article
Agriculture, Dairy & Animal Science
F. Ferrara, L. Tedin, R. Pieper, W. Meyer, J. Zentek
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2017)
Article
Agriculture, Dairy & Animal Science
K. M. S. Islam, M. Khalil, K. Manner, J. Raila, H. Rawel, J. Zentek, F. J. Schweigert
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2016)
Article
Agriculture, Dairy & Animal Science
R. Pieper, L. Scharek-Tedin, A. Zetzsche, I. Roehe, S. Kroeger, W. Vahjen, J. Zentek
JOURNAL OF ANIMAL SCIENCE
(2016)
Article
Biochemistry & Molecular Biology
A. Zetzsche, N. Schunter, J. Zentek, R. Pieper
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2016)
Article
Multidisciplinary Sciences
Nadine Passlack, Bettina Schmiedchen, Jens Raila, Florian J. Schweigert, Friederike Stumpff, Barbara Kohn, Konrad Neumann, Juergen Zentek
Article
Agriculture, Dairy & Animal Science
Nadine Passlack, Fenia Galliou, Thrassyvoulos Manios, Katia Lasaridi, Eleni Tsiplakou, Wilfried Vahjen, Juergen Zentek
Summary: The utilization of food residues in dog diets can affect the digestibility of protein and fats, increase short-chain fatty acid concentration in feces, and alter the composition of gut microbiota. Lower inclusion levels of up to 5% are recommended due to potential limitations in nutrient digestibility at higher levels.
ARCHIVES OF ANIMAL NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Carola Ellner, Beatriz Martinez-Vallespin, Eva-Maria Saliu, Juergen Zentek, Ilen Roehe
Summary: The study investigated the effects of rye and rapeseed meal (RSM) containing feed on growth performance, protein and amino acid digestibility, physical characteristics of the digesta, and the intestinal morphology in weaner piglets. Results showed that rye did not affect performance, while RSM resulted in reduced weight gain and feed intake. Additionally, both rye and RSM decreased the apparent ileal digestibility of crude protein and amino acids.
ARCHIVES OF ANIMAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Zeyang Li, Quentin L. Sciascia, Solvig Goers, Nga Nguyen, Farahnaz Rayatdoost Baghal, Johannes Schregel, Armin Tuchscherer, Juergen Zentek, Cornelia C. Metges
Summary: This study found that neonatal glutamine supplementation can improve growth and milk intake in low birth weight piglets, and also affect lipid and amino acid metabolism.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Plant Sciences
Dominik Popowski, Juergen Zentek, Jakub P. Piwowarski, Sebastian Granica
Summary: The study investigated the influence of pig intestinal microbiota on the structure of active compounds in flowers of Filipendula ulmaria and leaves of Orthosiphon aristatus, revealing the formation of anti-inflammatory and diuretic compounds through metabolism, suggesting potential for treating urinary tract disorders in piglets.
Article
Agriculture, Dairy & Animal Science
Carola Ellner, Anna G. Wessels, Juergen Zentek
Summary: Rye and rapeseed meal can be used as alternative feed components for weaner piglets, helping to maintain gut health and prevent diarrhea. Rye increases fermentative activity, while rapeseed meal reduces bacterial metabolic activity due to its high amount of insoluble dietary fiber.
Article
Biochemistry & Molecular Biology
Nadine Passlack, Louisa Verena Thies, Wilfried Vahjen, Juergen Zentek
Summary: The protein concentration and quality in feline diets can affect the intestinal microbiota of cats. Increasing dietary protein concentrations can increase the abundance of certain bacteria and bacterial metabolites in the feces of cats. Lower protein quality diets were associated with higher bacterial diversity and abundance in the feces. High protein intakes in cats can lead to increased bacterial proteolytic activity and intestinal ammonium concentrations.
Article
Green & Sustainable Science & Technology
Elisavet Giamouri, George Papadomichelakis, Athanasios C. Pappas, Panagiotis E. Simitzis, Fenia Galliou, Nadine Passlack, Juergen Zentek, Katia Lasaridi, Kostas Fegeros, Thrassyvoulos Manios, Eleni Tsiplakou, George Zervas
Summary: The aim of this study was to investigate the effect of dietary inclusion of dried hotel residues (DHR) on the growth performance, blood biochemical parameters, and meat quality traits in finishing pigs. The results showed that the addition of DHR did not affect feed utilization and meat quality, supporting the use of DHR in pig feeding.
Article
Agriculture, Dairy & Animal Science
Alessandro Vastolo, Jonathan Riedmueller, Monica Isabella Cutrignelli, Juergen Zentek
Summary: Hemp oil as a source of polyunsaturated fatty acids shows positive effects on the fecal microbial population in animals.
Article
Agriculture, Dairy & Animal Science
Eva-Maria Saliu, Ronald Krieg, Beatriz Martinez-Vallespin, Annette Simon, Juergen Zentek
Summary: Adequate levels of dietary fibre can reduce the risk of intestinal health disorders in rabbits after weaning. This study investigated the impact of different lignocellulose and cellulose addition on the performance and intestinal traits of lactating does and weaned rabbits. The results showed that high lignocellulose inclusion was beneficial for does, but a lower addition was preferred for weaned rabbits.
ARCHIVES OF ANIMAL NUTRITION
(2022)