A ROS-mediated lysosomal–mitochondrial pathway is induced by ginsenoside Rh2 in hepatoma HepG2 cells

Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells

(2014) Xiao-Feng Yao et al.   FOOD AND CHEMICAL TOXICOLOGY

Camalexin-Induced Apoptosis in Prostate Cancer Cells Involves Alterations of Expression and Activity of Lysosomal Protease Cathepsin D

(2014) Basil Smith et al.   MOLECULES

Lysosomal membrane permeabilization: Carbon nanohorn-induced reactive oxygen species generation and toxicity by this neglected mechanism

(2014) Mei Yang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

AMP-activated protein kinase determines apoptotic sensitivity of cancer cells to ginsenoside-Rh2

(2014) Min-Jung Kim et al.   Journal of Ginseng Research

The Anticancer Effect of Cytotoxin 1 from Naja atra Cantor Venom is Mediated by a Lysosomal Cell Death Pathway Involving Lysosomal Membrane Permeabilization and Cathepsin B Release

(2013) Minyan Wu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

A ROS-mediated lysosomal–mitochondrial pathway is induced by a novel Amonafide analogue, 7c, in human Hela cervix carcinoma cells

(2013) Ke Shen et al.   CANCER LETTERS

SHOX triggers the lysosomal pathway of apoptosis via oxidative stress

(2013) G. Hristov et al.   HUMAN MOLECULAR GENETICS

TNF -induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation

(2013) J. Huai et al.   JOURNAL OF CELL SCIENCE

Lysosomal cell death at a glance

(2013) S. Aits et al.   JOURNAL OF CELL SCIENCE

Reactive oxygen species mediated ginsenoside Rg3- and Rh2-induced apoptosis in hepatoma cells through mitochondrial signaling pathways

(2012) Hye-Min Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Ginsenoside Rh2 Induces Human Hepatoma Cell Apoptosisvia Bax/Bak Triggered Cytochrome C Release and Caspase-9/Caspase-8 Activation

(2012) Xiao-Xi Guo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginsenoside Rh2 inhibits glioma cell proliferation by targeting microRNA-128

(2011) Nan Wu et al.   ACTA PHARMACOLOGICA SINICA

Lysosomes and lysosomal cathepsins in cell death

(2011) Urška Repnik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic

(2011) Sophie Denamur et al.   FREE RADICAL BIOLOGY AND MEDICINE

A New Class of Naphthalimide-Based Antitumor Agents That Inhibit Topoisomerase II and Induce Lysosomal Membrane Permeabilization and Apoptosis

(2010) Zhuo Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Coomassie Staining as Loading Control in Western Blot Analysis

(2010) Charlotte Welinder et al.   JOURNAL OF PROTEOME RESEARCH

Lysosomal–mitochondrial cross-talk during cell death

(2010) Urška Repnik et al.   MITOCHONDRION

B1, a Novel Amonafide Analogue, Overcomes the Resistance Conferred by Bcl-2 in Human Promyelocytic Leukemia HL60 Cells

(2010) X. Liang et al.   MOLECULAR CANCER RESEARCH

A lysosomal–mitochondrial death pathway is induced by solamargine in human K562 leukemia cells

(2010) Lingmei Sun et al.   TOXICOLOGY IN VITRO

Mitochondrial/lysosomal toxic cross-talk plays a key role in cisplatin nephrotoxicity

(2010) Jalal Pourahmad et al.   XENOBIOTICA

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pre-clinical antitumour evaluation of Biphosphinic Palladacycle Complex in human leukaemia cells

(2008) Carlos R. Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS