Article
Oncology
Tao Sun, Xiutong Lin, Guifang Zhang, Qingtao Qiu, Chengqiang Li, Yong Yin
Summary: The study found that in bilateral breast cancer radiotherapy, whole-arc plans on the Halcyon have better dosimetric advantages than partial-arc plans. Compared to the Trilogy, Halcyon's plans reduce high-dose volumes in the heart and left ventricle but increase the mean dose of the heart. Additionally, plans on the Halcyon significantly reduce delivery time.
RADIATION ONCOLOGY
(2021)
Article
Oncology
Colton Ladbury, Chunhui Han, An Liu, Jeffrey Y. C. Wong
Summary: The aim of this study is to report historical treatment planning experience at our institution for patients receiving total marrow and lymphatic irradiation (TMLI) using volumetric modulated arc therapy (VMAT) as part of the conditioning regimen prior to hematopoietic stem cell transplant. The results of the study showed that the dose distributions and treatment times of the VMAT TMLI plans were similar to those generated with helical tomotherapy. Therefore, VMAT technique can be effectively used for TMLI treatment, even at escalated doses.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Huai-wen Zhang, Bo Hu, Hao-wen Pang
Summary: This study compared the dosimetric advantages of helical tomotherapy (HT) and volumetric modulated arc therapy (VMAT) technology in hippocampal avoidance whole-brain radiotherapy. The results showed that HT technology had better dose distribution in terms of conformity and uniformity compared to VMAT technology, and reduced the radiation dose to organs at risk.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2023)
Article
Multidisciplinary Sciences
Xianfeng Liu, Furong Wu, Fu Jin, Fu Sun, Qicheng Li, Mingfang Guo, Xiujuan Zhao, Qishuai Guo
Summary: This study compares the dosimetric differences of restricting beamlets passing in protecting ovaries between helical tomotherapy (HT) and volumetric-modulated arc therapy (VMAT) for patients with cervical cancer. The results suggest that HT outperforms VMAT in terms of target coverage and organs at risk (OARs) sparing.
JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES
(2022)
Article
Oncology
Emily Keit, Casey Liveringhouse, Nicholas Figura, Joseph Weygand, Maria L. Sandoval, Genevieve Garcia, Julia Peters, Michael Nieder, Rawan Faramand, Farhad Khimani, Sungjune Kim, Timothy J. Robinson, Peter A. S. Johnstone, Jose Penagaricano, Kujtim Latifi
Summary: This study describes a new method of delivering high-dose total body irradiation (TBI) using VMAT technology and compares dosimetric outcomes with helical tomotherapy (HT) treatment. The study found that VMAT technique can achieve lower lung doses compared to HT treatment and demonstrate the possibility of selective organ-at-risk (OAR) sparing to reduce TBI-related morbidity and mortality.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2023)
Article
Medicine, General & Internal
Rui Wang, Jun Shen, Huanhuan Yan, Xitao Gao, Tianfu Dong, Shuqin Li, Peishun Wang, Jun Zhou
Summary: This study found that VMAT plans were superior to IMRT plans in treating left-sided breast cancer patients after modified radical mastectomy. VMAT plans had better target volume coverage and conformity, and were more effective in sparing the heart. Additionally, VMAT plans reduced treatment time.
Article
Oncology
Alparslan Serarslan, Yalcin Dastan, Telat Aksu, Rana Elif Yildiz, Bilge Gursel, Deniz Meydan, Nilguen Ozbek Okumus
Summary: A new technique called 90 degrees angled collimated dynamic IMRT (A-IMRT) was developed to better protect organs at risk (OARs) by turning the collimator angle to 90 degrees. Compared to conventional dynamic IMRT (C-IMRT), A-IMRT significantly reduced the dose constraints exceeded for the bladder, rectum, and bilateral femoral heads.
Article
Engineering, Biomedical
Pinar Dursun, Masoud Zarepisheh, Gourav Jhanwar, Joseph O. Deasy
Summary: The proposed method utilizes a sequential convex programming algorithm to solve the non-convex VMAT problem efficiently, with both local and global search strategies. The algorithm demonstrates good performance in clinical cases.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Oncology
Melek Akcay, Durmus Etiz, Kerem Duruer, Ozge Bozdogan, Alaattin Ozen
Summary: The study aimed to compare the differences between IMRT and VMAT techniques in locally advanced NSCLC patients. Results showed that the two techniques have different advantages in treating different types of lung tumors.
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
(2021)
Article
Oncology
Nalee Kim, Jee Suk Chang, Chirag Shah, Hyejung Shin, Ki Chang Keum, Chang-Ok Suh, Yong Bae Kim
Summary: The study showed that for breast cancer patients undergoing adjuvant radiotherapy, HF-VMAT had significant advantages in reducing acute and late toxicities compared to CF-3D or HF-3D, especially in patients receiving regional node irradiation.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Qian Chen, Lingwei Tang, Zhe Zhu, Liangfang Shen, Shan Li
Summary: This study compared the dosimetric parameters and clinical outcomes between volumetric modulated arc therapy (VMAT) and tomotherapy for late T-stage nasopharyngeal carcinoma (NPC). The results showed that tomotherapy had better dosimetric parameters and better short-term efficacy compared to VMAT, with lower incidence of acute mucositis. However, there were no significant differences in survival outcomes between the two treatment groups.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Vincent Bourbonne, Alice Delafoy, Francois Lucia, Gilles Quere, Olivier Pradier, Ulrike Schick
Summary: Intensity-modulated radiotherapy has replaced 3D-RT in many tumor sites, leading to better target dose conformity and organ sparing, but potentially increasing low dose volume to normal tissues. This study retrospectively analyzed pulmonary and esophageal toxicities in lung cancer patients treated with VMAT, showing low rates of toxicity and significant associations with specific factors on multivariate analysis. Larger prospective studies are needed to verify these findings.
TRANSLATIONAL LUNG CANCER RESEARCH
(2021)
Article
Oncology
Shengpeng Jiang, Yi Xue, Ming Li, Chengwen Yang, Daguang Zhang, Qingxin Wang, Jing Wang, Jie Chen, Jinqiang You, Zhiyong Yuan, Xiaochun Wang, Xiaodong Zhang, Wei Wang
Summary: This study investigated the use of artificial intelligence-based automated treatment planning to generate high-quality postmastectomy VMAT plans. The automated plans showed significant improvements in target volume uniformity and conformity, as well as dose to the heart and lungs compared to manual clinical plans.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
G. Smyth, S. Mowat, K. Chia, K. Robinson, K. Warren-Oseni, L. C. Welsh, I Blasiak-Wal, H. C. Mandeville
Summary: This study aimed to evaluate the safety and accuracy of using CSI-VMAT in a commercially available treatment planning system. The initial clinical experience showed that the technique is feasible for patients undergoing craniospinal irradiation, with the limitation being the available beam overlap length in the neck.
Article
Chemistry, Multidisciplinary
Na-Hyun Hwang, Myungsoo Kim, Nam Kwon Lee, Suk Lee, Jinho Hwang
Summary: This study compares the dosimetric effects of traditional metallic ports and RFID ports in post-mastectomy VMAT planning for left-sided breast cancer. The results demonstrate that RFID ports significantly reduce distortions on CT images and result in lower doses to the heart and lungs.
APPLIED SCIENCES-BASEL
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
A. Clough, J. Sanders, K. Banfill, C. Faivre-Finn, G. Price, C. L. Eccles, M. C. Aznar, M. Van Herk
Summary: Thoracic CT plays a crucial role in the early diagnosis of COVID-19 patients. The study shows that COVID-19 infection can be detected on CBCT, providing assistance in patient management and staff protection.
Article
Oncology
A. Abravan, A. Salem, G. Price, C. Faivre-Finn, M. van Herk
Summary: This study suggests that baseline NLR and SII are independent prognostic biomarkers associated with overall survival in locally advanced and early-stage NSCLC patients treated with either curative-intent fractionated RT or SBRT and SCLC patients treated with curative-intent fractionated RT.
Article
Radiology, Nuclear Medicine & Medical Imaging
Rosie B. Hales, Robert Chuter, Alan McWilliam, Amal Salah, Michael Dubec, Linnea Freear, Lisa McDaid, Marianne Aznar, Marcel van Herk, Andrew McPartlin, Cynthia L. Eccles
Summary: This study evaluated the dosimetric impact of gadolinium-based contrast agents (GBCAs) on head and neck radiation therapy plans using retrospective datasets. The results showed minimal dose differences to targets and organs at risk, suggesting that prospective evaluations of GBCA impact may not be necessary in clinical practice for oropharyngeal cancer treatment.
Article
Engineering, Biomedical
Benjamin K. F. Lau, Tess Reynolds, Paul J. Keall, Jan-Jakob Sonke, Shalini K. Vinod, Owen Dillon, Ricky T. O'Brien
Summary: This study investigates the dose and time limits of adaptive 4DCBCT acquisitions compared with current conventional 4DCBCT acquisition. The results show that adaptive-acquisition with lower imaging dose and faster scan time can achieve equivalent or improved image quality compared to conventional-acquisition.
PHYSICS IN MEDICINE AND BIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rebecca Benson, John Rodgers, Claire Nelder, Abigael Clough, Eleanor Pitt, Jacqui Parker, Lee Whiteside, Lucy Davies, Rachael Bailey, John Mcmahon, Hope Kolbe, Anthea Cree, Michael Dubec, Marcel Van Herk, Ananya Choudhury, Peter Hoskin, Cynthia Eccles
Summary: This study compares the impact of a dedicated educational tool versus experience gained in MR-guided radiotherapy on image registration in cervical cancer patients. The results show no significant differences between imaging modalities, while there was a significant reduction in interobserver variability in MR-MR imaging and an increase in observer confidence in all three modalities.
BRITISH JOURNAL OF RADIOLOGY
(2022)
Article
Oncology
Matthew Craddock, Ursula Nestle, Jochem Koenig, Tanja Schimek-Jasch, Stephanie Kremp, Stefan Lenz, Kathryn Banfill, Angela Davey, Gareth Price, Ahmed Salem, Corinne Faivre-Finn, Marcel van Herk, Alan McWilliam
Summary: This study analyzes the overall survival of patients with inoperable stage II or III NSCLC treated with radiotherapy, and for the first time includes left ventricular ejection fraction as a metric of cardiac function. The results indicate that there is a region within the base of the heart that is significantly associated with worse overall survival, and an interaction between baseline cardiac health and heart base dose was identified.
JOURNAL OF THORACIC ONCOLOGY
(2023)
Article
Oncology
Alan McWilliam, Azadeh Abravan, Kathryn Banfil, Corinne Faivre-Finn, Marcel van Herk
Summary: The dose to the base of the heart is associated with overall survival, explaining the worse survival in the high-dose arm of lung cancer treatment. By avoiding the heart subregion dose, future dose escalation trials may be feasible.
JOURNAL OF THORACIC ONCOLOGY
(2023)
Article
Engineering, Biomedical
Carlos Huesa-Berral, Celia Juan-Cruz, Simon van Kranen, Maddalena Rossi, Jose Belderbos, Juan Diego Azcona, Javier Burguete, Jan-Jakob Sonke
Summary: This study evaluates and validates the dosimetric effect of respiratory motion and inter-fraction variations in SBRT using 4D-CT and daily 4D-CBCT dose accumulation scenarios. The results show that both 4D-Acc and 3D-Acc have an impact on the dose, especially in the tumor and organs at risk region. The effectiveness of CT-CBCT deformable image registration techniques is also validated.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Oncology
Eliana Vasquez Osorio, Azadeh Abravan, Andrew Green, Marcel van Herk, Lip Wai Lee, Deborah Ganderton, Andrew Mcpartlin
Summary: This study explores the relationship between radiation therapy dose to normal head and neck structures and dysphagia after treatment. The results suggest that the mean dose to the inferior section of the brain stem is strongly associated with dysphagia 1 year posttreatment, possibly due to its involvement with the swallowing centers in the medulla oblongata.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2023)
Letter
Oncology
Alan McWilliam, Azadeh Abravan, Kathryn Banfill, Corinne Faivre-Finn, Marcel van Herk
JOURNAL OF THORACIC ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jennifer Robbins, Marcel van Herk, Bjorn Eiben, Andrew Green, Eliana Vasquez Osorio
Summary: This study aimed to create time-varying prediction models to describe both the average and residual anatomical deformations. Weekly population-based principal component analysis models were generated from on-treatment conebeam CT scans of head and neck cancer patients, and validated using additional patient data. The results showed that set-up uncertainties had a larger effect on organ at risk (OAR) doses than anatomical deformations, and the simulated results were in good agreement with the accumulated dose distribution. These models can be used to predict which patients could benefit from adaptive radiotherapy prior to treatment.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2023)
Article
Engineering, Biomedical
Edward G. A. Henderson, Eliana M. Vasquez Osorio, Marcel van Herk, Charlotte L. Brouwer, Roel J. H. M. Steenbakkers, Andrew F. Green
Summary: Automatic segmentation of organs-at-risk in radiotherapy planning CT scans using CNNs is an active research area. Large, high-quality datasets are scarce in radiotherapy, and combining data from multiple sources may reduce training segmentation consistency. Understanding the impact of training data quality is important for auto-segmentation models in radiotherapy.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Oncology
Michael J. Dubec, David L. Buckley, Michael Berks, Abigael Clough, John Gaffney, Anubhav Datta, Damien J. McHugh, Nuria Porta, Ross A. Little, Susan Cheung, Christina Hague, Cynthia L. Eccles, Peter J. Hoskin, Robert G. Bristow, Julian C. Matthews, Marcel van Herk, Ananya Choudhury, Geoff J. M. Parker, Andrew McPartlin, James P. B. O'Connor
Summary: The study aimed to develop oxygen-enhanced MRI (OE-MRI) in head and neck cancer patients and translate the technique onto an MR Linac system. The results showed that OE-MRI was feasible and had good repeatability, and it has the potential to guide future clinical trials of biology guided adaptive radiotherapy.
RADIOTHERAPY AND ONCOLOGY
(2023)
Meeting Abstract
Oncology
M. J. Dubec, J. Gaffney, A. Datta, D. L. Buckley, R. Little, A. Clough, C. Hague, M. Berks, S. Cheung, A. Salah, C. L. Eccles, R. G. Bristow, D. Higgins, J. H. Naish, J. Matthews, M. van Herk, G. J. Parker, A. Choudhury, J. P. O'Connor, A. McPartlin
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2022)
Proceedings Paper
Computer Science, Interdisciplinary Applications
Edward G. A. Henderson, Andrew F. Green, Marcel van Herk, Eliana M. Vasquez Osorio
Summary: This study aimed to develop a tool to automatically identify errors in the segmentation of organs-at-risk (OARs) in CT scans without a ground truth. The proposed model, which combines convolutional neural networks (CNNs) and graph neural networks (GNNs), achieved high precision and recall in predicting errors in the segmentation of the parotid gland.
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION, MICCAI 2022, PT V
(2022)
Article
Oncology
Derek A. Mumaw, Allison J. Hazy, Aleksander Vayntraub, Thomas J. Quinn, Kamran Salari, John H. Chang, Noah Kalman, Sanford Katz, James Urbanic, Robert H. Press, Arpi Thukral, Henry Tsai, George E. Laramore, Jason Molitoris, Carlos Vargas, Samir H. Patel, Craig Stevens, Rohan L. Deraniyagala
Summary: This study evaluated contralateral recurrences in patients with oropharyngeal squamous cell carcinoma who received unilateral proton beam therapy. The results showed a favorable contralateral neck failure rate that was comparable to photon irradiation.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Kangpyo Kim, Dongryul Oh, Jae Myoung Noh, Yang Won Min, Hong Kwan Kim, Yong Chan Ahn
Summary: This study suggests that hypofractionated radiation therapy alone is a feasible option for early stage esophageal squamous cell carcinoma patients. Particularly, in patients with tumor length < 3 cm, this treatment scheme shows favorable local control rates with low incidence of esophageal toxicities.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Lin Chen, Jing Li, Kunpeng Li, Jiang Hu, Qingjie Li, Chenglong Huang, Gaoyuan Wang, Na Liu, Linglong Tang
Summary: This study analyzed the probability of hearing impairment after radiotherapy for nasopharyngeal carcinoma and developed a predictive model, providing dose limitation suggestions to improve patients' quality of life.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Yiwei Yang, Jianxin Wang, Feng Gao, Zhen Liu, Tangzhi Dai, Haowen Zhang, Hongyu Zhu, Tingting Wang, Dexin Xiao, Kui Zhou, Zheng Zhou, Dai Wu, Xiaobo Du, Sen Bai
Summary: This paper provides a comprehensive description of the current status of PARTER, which is the first experimental FLASH platform utilizing megavoltage X-rays. It showcases the reliable performance and stability of the dosimeters and monitors used in PARTER, as well as the satisfactory dose distribution and characteristics of the FLASH X-rays. The platform effectively meets the requirements of preclinical research on megavoltage X-ray FLASH and undergoes continuous upgrades.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Maria Thor, Kelly Fitzgerald, Aditya Apte, Jung Hun Oh, Aditi Iyer, Otasowie Odiase, Saad Nadeem, Ellen D. Yorke, Jamie Chaft, Abraham J. Wu, Michael Offin, Charles B. Simone Ii, Isabel Preeshagul, Daphna Y. Gelblum, Daniel Gomez, Joseph O. Deasy, Andreas Rimner
Summary: The purpose of this study was to identify predictors of disease progression in early-stage non-small cell lung cancer (NSCLC) patients after receiving definitive stereotactic body radiation therapy (SBRT). The results showed that tumor diameter and SUVmax were the most frequently reported features associated with progression/survival, and a re-fitted model including these two features had the best performance.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Yong-Qiao He, Tong-Min Wang, Da-Wei Yang, Wen-Qiong Xue, Chang-Mi Deng, Dan-Hua Li, Wen-Li Zhang, Ying Liao, Ruo-Wen Xiao, Lu-Ting Luo, Hua Diao, Xia-Ting Tong, Yan-Xia Wu, Xue-Yin Chen, Jiang-Bo Zhang, Ting Zhou, Xi-Zhao Li, Pei-Fen Zhang, Xiao-Hui Zheng, Shao-Dan Zhang, Ye-Zhu Hu, Guan-Qun Zhou, Jun Ma, Ying Sun, Wei-Hua Jia
Summary: In this study, researchers aimed to establish a predictive model for radiation-induced brain injury (RBI) in nasopharyngeal carcinoma (NPC) patients by incorporating clinical factors and newly developed genetic variants. They conducted a large-scale retrospective study and a genome-wide association study to develop a polygenic risk score (PRS) for RBI risk prediction. The results showed that the PRS, combined with clinical factors, improved the accuracy of RBI risk stratification and suggested personalized radiotherapy.
RADIOTHERAPY AND ONCOLOGY
(2024)
Review
Oncology
Xiaoyong Xiang, Zhe Ji, Jing Jin
Summary: A review of studies suggests that brachytherapy as a salvage therapy for recurrent glioblastoma shows acceptable safety and good post-treatment clinical efficacy for selected patients.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
M. Berbee, C. T. Muijs, F. E. M. Voncken, L. Wee, M. Sosef, B. van Etten, J. W. van Sandick, F. A. R. M. Warmerdam, J. J. de Haan, E. Oldehinkel, J. M. van Dieren, L. Boersma, J. A. Langendijk, A. van der Schaaf, J. B. Reitsma, E. Schuit
Summary: This study externally validated a model for predicting 2-year total mortality in lung cancer patients in esophageal cancer patients. The intercept and/or slope of the original model needed adjustment to achieve good performance in esophageal cancer patients.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Dominique Reijtenbagh, Jeremy Godart, Joan Penninkhof, Sandra Quint, Andras Zolnay, Jan-Willem Mens, Mischa Hoogeman
Summary: This study compared the performance of the current PotD strategy with non-adaptive and fully online-adaptive techniques in the treatment of cervical cancer patients. The findings show that the PotD protocol is effective in improving normal tissue sparing compared to no adaptation, while fully online-adaptive approaches can further reduce target volume but come with a more complex workflow.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Albrecht Weiss, Steffen Loeck, Ting Xu, Zhongxing Liao, Aswin L. Hoffmann, Esther G. C. Troost
Summary: Traditional models for predicting radiation pneumonitis may not be applicable to non-small cell lung cancer patients treated with passively-scattered proton therapy. The use of effective alpha/beta parameter can predict the occurrence of radiation pneumonitis in these patients.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Z. A. R. Gouw, J. Jeong, A. Rimner, N. Y. Lee, A. Jackson, A. Fu, J-j. Sonke, J. O. Deasy
Summary: This study investigates the effectiveness of non-uniform fractionation schedules in radiotherapy for early-stage non-small cell lung cancer. Through modeling, optimized schedules are proposed to minimize local failures and toxicity risk. The results suggest that non-standard primer shot fractionation can reduce hypoxia-induced radioresistance and improve treatment outcomes.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Sara Ronchi, Alessandro Cicchetti, Maria Bonora, Rossana Ingargiola, Anna Maria Camarda, Stefania Russo, Sara Imparato, Paolo Castelnuovo, Ernesto Pasquini, Piero Nicolai, Mohssen Ansarin, Michele Del Vecchio, Marco Benazzo, Ester Orlandi, Barbara Vischioni
Summary: This study evaluates the efficacy and toxicity of carbon ion radiotherapy (CIRT) in locally advanced head and neck mucosal melanoma patients. The results show that CIRT is safe and effective in treating the local region, and immunotherapy after relapse can improve overall survival. However, further prospective trials are needed to assess the role of targeted/immune- systemic therapy in this disease.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Dominik Wawrzuta, Justyna Klejdysz, Marzanna Chojnacka
Summary: This study analyzed articles about radiation oncology published in The New York Times since its inception in 1851, and identified changes in media sentiment and prevalent themes related to radiotherapy. The findings suggest an increasing negative sentiment in media coverage towards radiotherapy, with a shift towards reporting treatment errors, toxicity, and ineffectiveness.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Elaine Limkin, Pierre Blanchard, Benjamin Lacas, Jean Bourhis, Mahesh Parmar, Lisa Licitra, Quynh-Thu Le, Sue S. Yom, Catherine Fortpied, Johannes Langendijk, Jan B. Vermorken, Jacques Bernier, Jens Overgaard, Jonathan Harris, Jean-Pierre Pignon, Anne Auperin
Summary: This study investigated the impact of season of radiotherapy on the outcomes of head and neck squamous cell cancer patients. The results showed that the season of radiotherapy did not have any significant effect on patient outcomes.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Fabio L. Cury, Gustavo A. Viani, Andre G. Gouveia, Camila V. S. Freire, Gabriel de A. Grisi, Fabio Y. Moraes
Summary: In limb-sparing treatment of soft tissue sarcoma patients, a 5-day course of preoperative radiotherapy results in high local control and favorable R0 margins, with acceptable complication rates, particularly for patients receiving higher biological equivalent doses.
RADIOTHERAPY AND ONCOLOGY
(2024)
