Article
Radiology, Nuclear Medicine & Medical Imaging
Guangyi Wang, Wanwei Jian, Xiaoping Cen, Lijuan Zhang, Hui Guo, Zaiyi Liu, Changhong Liang, Wu Zhou
Summary: The study explored the value of diffusion-weighted magnetic resonance imaging in predicting microvascular invasion of hepatocellular carcinoma using Convolutional Neural Networks. Results showed that the fusion of deep features from different b-value images yielded the best performance for MVI prediction.
ACADEMIC RADIOLOGY
(2021)
Article
Clinical Neurology
J. B. M. Warntjes, P. Lundberg, A. Tisell
Summary: In this study, a 3D MR imaging quantification sequence was used to synthesize a T1-weighted image stack for brain volume measurement. The repeatability and reproducibility of using the conventional and synthetic input data were evaluated.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Mengyu Song, Qi Wang, Hui Feng, Lijia Wang, Yunfei Zhang, Hui Liu
Summary: This study aimed to use various DWI techniques for the preoperative grading of rectal cancer. The results showed significant differences in IVIM and DKI-derived parameters between low-grade and high-grade rectal cancer. The use of machine learning classifiers proved valuable for noninvasive grading.
BIOENGINEERING-BASEL
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Myoung Seok Lee, Min Hoan Moon, Sang Youn Kim, Siwon Jang, Sohee Oh, Jeong Yeon Cho
Summary: The purpose of this study was to compare the use of CE MRI and DWI in the risk stratification of women with endometrial cancer for lymph node metastasis. The results showed no significant difference between CE MRI and DWI in the rate of lymph node metastasis according to the risk stratification, suggesting that DWI may be a comparable alternative to CE MRI.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Oncology
Chunlong Fu, Tingting Shao, Min Hou, Jiali Qu, Ping Li, Zebin Yang, Kangfei Shan, Meikang Wu, Weida Li, Xuan Wang, Jingfeng Zhang, Fanghong Luo, Long Zhou, Jihong Sun, Fenhua Zhao
Summary: This study aimed to establish an effective model for preoperative prediction of tumor deposits (TDs) in patients with rectal cancer (RC). ML-based and DL-based radiomic models were developed and integrated with clinical characteristics for TD prediction. The comprehensive model achieved promising performance and has the potential to assist in preoperative evaluation and personalized treatment of RC patients.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Minghao Zhong, Zhiqi Yang, Xiaofeng Chen, Ruibin Huang, Mengzhu Wang, Weixiong Fan, Zhuozhi Dai, Xiangguang Chen
Summary: This study aimed to compare the ability of RS-EPI and conventional SS-EPI to differentiate receptor statuses in breast MRI. The results showed that ADC measurements were higher on RS-EPI compared to SS-EPI, and RS-EPI was able to better distinguish between HER-2-positive and HER-2-negative breast cancer.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Oncology
Junjiao Hu, Xin Yu, Peidi Yin, Bin Du, Xiangran Cai
Summary: This study evaluated the predictive value of IVIM diffusion-weighted imaging (DWI) in assessing the immune responses induced by immunogenic chemotherapy. The results showed that IVIM-DWI can effectively evaluate the treatment response and the D value may serve as a sensitive imaging marker for identifying the antitumor immune response initiated by immunogenic chemotherapy.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yi Yuan, Hong Pu, Guang-wen Chen, Xiao-li Chen, Yi-Sha Liu, Hao Liu, Kang Wang, Hang Li
Summary: The study aimed to determine the diagnostic performance of DW-MRI volume and ADC values in assessing LNM and good response after CRT in LARC patients. The results showed that DW-MRI Δ volume provided high diagnostic performance in discriminating LNM after CRT, and was equally accurate as post-CRT DW-MRI volume for evaluating good response.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jong Keon Jang, Chul-min Lee, Seong Ho Park, Jong Hoon Kim, Jihun Kim, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
Summary: The study determined an algorithm for combining T2WI and DWI to more accurately assess complete response to chemoradiotherapy for rectal cancer. The AND combination showed higher diagnostic efficiency, while the OR and conditional OR combinations increased sensitivity but decreased specificity, leading to more false interpretations of complete response.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Article
Oncology
Soo-Yoon Sung, Sea-Won Lee, Ji Hyung Hong, Hye Jin Kang, So Jung Lee, Myungsoo Kim, Ji-Hoon Kim, Yoo-Kang Kwak
Summary: We assessed the pattern of tumor regression during neoadjuvant chemoradiotherapy (CCRT) using daily MRI and found that tumor regression velocity may serve as a biomarker for real-time treatment response and further treatment decision in locally advanced rectal cancer. This study is the first to observe linear tumor regression in daily MRI during CCRT and suggests the potential value of daily tumor volumetry in treatment decisions.
Article
Neurosciences
A. Ianus, D. C. Alexander, H. Zhang, M. Palombo
Summary: This study investigates the impact of cell body size and branching of cellular projections on diffusion MR imaging and spectroscopy signals, finding that spherical soma size significantly affects SDE signal and MD, MK, while branching order has a minor impact on water. DDE measurements may be more sensitive to branching order, paving the way for new ways of characterizing grey matter morphology non-invasively using dMRS and potentially dMRI.
Article
Radiology, Nuclear Medicine & Medical Imaging
Shivani Ahlawat, Julie Paik, Filippo Del Grande, Elias S. Paris, Parvinder Sujlana, Laura M. Fayad
Summary: In patients with fibrosing systemic sclerosis-associated myopathy, intramuscular and fascial edema are more common on MRI, while patients with non-fibrosing myopathy often exhibit fatty replacement and atrophy.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sevtap Arslan, Fatma Bilge Ergen, Guzide Burca Aydin, Mehmet Ayvaz, Jale Karakaya, Kemal Kosemehmetoglu, Adalet Elcin Yildiz, Ustun Aydingoz
Summary: This study compared the diagnostic performance of m-DWI, IVIM, and DK models and their combinations in differentiating benign and malignant musculoskeletal tumors, finding that certain parameters can be used to differentiate between different types of tumors.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jaeseung Shin, Nieun Seo, Song-Ee Baek, Nak-Hoon Son, Joon Seok Lim, Nam Kyu Kim, Woong Sub Koom, Sungwon Kim
Summary: This study evaluated radiomics models based on T2-weighted imaging and diffusion-weighted MRI for predicting pCR after nCRT in LARC and compared their performance with visual assessment by radiologists. The results showed that the MRI-based radiomics model had better classification performance than experienced radiologists for diagnosing pathologic complete response in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy.
Article
Oncology
Zanxia Zhang, Jie Liu, Weijian Wang, Yong Zhang, Feifei Qu, Tom Hilbert, Tobias Kober, Jingliang Cheng, Shujian Li, Jinxia Zhu
Summary: This study aimed to determine the quantitative T2 values in endometrial carcinoma (EMC) and evaluate their potential for detection, classification, and grading. The results showed significantly lower T2 values in EMC compared to normal endometrium. T2 values could differentiate different pathological features of EMC, while ADC values could not. Combining T2 and ADC values improved the prediction of histological grades in endometrioid adenocarcinoma (EA).
FRONTIERS IN ONCOLOGY
(2023)
Article
Surgery
Sanne-Marije Hazen, Tania Sluckin, Geerard Beets, Roel Hompes, Pieter Tanis, Miranda Kusters
Summary: There is significant variation among Dutch colorectal surgeons in the assessment and treatment of lateral lymph nodes in rectal cancer patients, highlighting the need for further research and international guidelines.
ACTA CHIRURGICA BELGICA
(2023)
Article
Oncology
Karel C. Smit, Jeroen W. G. Derksen, Geerard L. O. Beets, Eric J. Th. Belt, Maaike Berbee, Peter Paul L. O. Coene, Hester van Cruijsen, Marjan A. Davidis, Jan Willem T. Dekker, Joyce M. van Dodewaard-de Jong, Annebeth W. Haringhuizen, Helgi H. Helgason, Mathijs P. Hendriks, Ronald Hoekstra, Ignace H. J. T. de Hingh, Jan N. M. IJzermans, Johan J. B. Janssen, Joop L. M. Konsten, Maartje Los, Leonie J. M. Mekenkamp, Peter Nieboer, Koen C. M. J. Peeters, Natascha A. J. B. Peters, Hans J. F. M. Pruijt, Patricia Quarles van Ufford-Mannesse, Ron C. Rietbroek, Anandi H. W. Schiphorst, Arjan Schouten van der Velden, Ruud W. M. Schrauwen, Mark P. S. Sie, Dirkje W. Sommeijer, Dirk J. A. Sonneveld, Hein B. A. C. Stockmann, Marleen Tent, Frederiek Terheggen, Manuel L. R. Tjin-A-Ton, Liselot Valkenburg-van Iersel, Ankie M. T. van der Velden, Wouter J. Vles, Theo van Voorthuizen, Johannes A. Wegdam, Johannes H. W. de Wilt, Miriam Koopman, Anne M. May
Summary: Physical activity is associated with longer survival among non-metastasized colorectal cancer patients. This study aimed to investigate whether physical activity is also beneficial for survival among patients with metastatic colorectal cancer (mCRC). The study found that higher levels of physical activity at the time of mCRC diagnosis were associated with longer overall survival. Adherence to physical activity guidelines for cancer survivors was also related to prolonged survival. Future research is needed to examine whether improving exercise levels after the diagnosis of metastasis is beneficial and determine the most effective exercise interventions for improving survival time in mCRC patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Nino Bogveradze, Monique Maas, Najim el Khababi, Niels W. Schurink, Max J. Lahaye, Frans C. H. Bakers, Pieter J. Tanis, Miranda Kusters, Geerard L. Beets, Regina G. H. Beets-Tan, Doenja M. J. Lambregts
Summary: Combining CT with MRI, especially for junior readers, can provide more confidence in using STO to localize rectal and sigmoid cancers, thus improving diagnostic accuracy.
Article
Gastroenterology & Hepatology
Rutger C. H. Stijns, Jeroen Leijtens, Eelco de Graaf, Simon P. Bach, Geerard Beets, Andre J. A. Bremers, Regina G. H. Beets-Tan, Johannes H. W. de Wilt
Summary: This study aimed to evaluate the diagnostic accuracy of different methods for assessing treatment response in early rectal cancer patients after neoadjuvant chemoradiotherapy. The results showed that a multimodality approach combining endoscopy and (DWI) MRI achieved the most accurate assessment of treatment response.
COLORECTAL DISEASE
(2023)
Article
Oncology
Merel A. Spiekerman van Weezelenburg, Loeki Aldenhoven, Sander M. J. van Kuijk, Geerard L. Beets, James van Bastelaar
Summary: The study found that using a minimum of 15 sutures spaced approximately 3.7 cm apart during mastectomy can significantly reduce the incidence of seroma formation. Surgical technique and flap fixation both play a crucial role in preventing seromas after mastectomy.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Laura M. Fernandez, Guilherme P. Sao Julio, Andrew G. Renehan, Geerard L. Beets, Ana L. Papoila, Bruna B. Vailati, Renu R. Bahadoer, Elma Meershoek-Klein Kranenbarg, Annet G. H. Roodvoets, Nuno L. Figueiredo, Cornelis J. H. Van de Velde, Angelita Habr-Gama, Rodrigo O. Perez
Summary: This study retrospectively reviewed data from an international watch and wait database and found that local regrowth is a risk factor for distant metastases in patients with rectal cancer. Patients remain at higher risk for distant metastases for 5 years after the development of local regrowth.
DISEASES OF THE COLON & RECTUM
(2023)
Review
Medicine, General & Internal
Ana P. Borges, Celia Antunes, Filipe Caseiro-Alves
Summary: Using different energy levels, dual-energy computed tomography (DECT) enables the differentiation of materials, improves image quality and iodine visibility, and allows researchers to determine iodine contrast and reduce radiation dose. Commercial DECT platforms with various acquisition techniques are continuously being improved. DECT has wide-ranging clinical applications and benefits in various diseases. This review focuses on the current applications and challenges of DECT in the treatment of liver diseases. The advantages of DECT include better contrast and iodine quantification for lesion detection, accurate staging, treatment response assessment, and thrombi characterization. However, there are limitations such as reduced image quality for larger body sizes, variability across different vendors and scanners, and long reconstruction time. Promising techniques for improving image quality with lower radiation dose include deep learning imaging reconstruction and spectral photon-counting computed tomography.
Meeting Abstract
Oncology
Y. L. Verschoor, J. Van den Berg, S. Balduzzi, J. C. Van Blijderveen, S. Oosterling, P. Burger, T. Aukema, T. Vogten, S. Dokter, R. Beets-Tan, A. V. Lent, G. Beets, M. Van Leerdam, J. B. A. G. Haanen, M. Chalabi
ANNALS OF ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Najim El Khababi, Regina G. H. Beets-Tan, Renaud J. Tissier, Max Lahaye, Monique Maas, Luis Curvo-Semedo, Raphaela C. Dresen, Stephanie L. Nougaret, Geerard Beets, Doenja M. J. Lambregts, Rectal MRI Study Grp
Summary: The study aimed to investigate the value of rectal cancer T-staging on MRI in relation to fibrotic transformation of the tumour bed. The results showed that ymrT-staging has moderate accuracy, with higher accuracy in patients with predominant fibrosis. Therefore, radiologists should focus on detecting residual disease and identifying potential candidates for organ preservation.
COLORECTAL DISEASE
(2023)
Article
Medicine, General & Internal
Tania C. Sluckin, Marije Hekhuis, Sabrine Q. Kol, Joost Nederend, Karin Horsthuis, Regina G. H. Beets-Tan, Geerard L. Beets, Jacobus W. A. Burger, Jurriaan B. Tuynman, Harm J. T. Rutten, Miranda Kusters, Sean Benson
Summary: This study developed an artificial intelligence model to predict the risk of (L)LR in rectal cancer patients by combining imaging and clinical features, providing a basis for identifying high-risk patients and developing risk stratification models.
Review
Radiology, Nuclear Medicine & Medical Imaging
Ana P. P. Borges, Celia Antunes, Luis Curvo-Semedo
Summary: Dual-energy computed tomography (DECT) uses different energy spectrum x-ray beams to differentiate materials with similar attenuation. It provides better diagnostic performance and potential reduction of contrast agent and radiation doses compared to single-energy CT. This narrative review discusses the DECT technique, including physical concepts, parameters influencing image quality, postprocessing methods, applicability in daily routine workflow, and radiation considerations. Differences between scanners, current clinical applications, and future perspectives are also described.
Meeting Abstract
Oncology
Yara L. Verschoor, Doenja M. J. Lambregts, Jose van den Berg, Brechtje A. Grotenhuis, Arend Aalbers, Baukelien Van Triest, Regina G. H. Beets-Tan, Marieke van de Belt, Simone Dokter, Sara Balduzzi, Emile E. Voest, John B. A. G. Haanen, Monique E. van Leerdam, Geerard Beets, Myriam Chalabi
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Letter
Gastroenterology & Hepatology
Laura M. Fernandez, Guilherme P. Sao Juliao, Andrew G. Renehan, Geerard L. Beets, Ana L. Papoila, Bruna B. Vailati, Elma Meershoek-Klein Kranenbarg, Annet G. H. Roodvoets, Nuno L. Figueiredo, Cornelis J. H. van de Velde, Angelita Habr-Gama, Rodrigo O. Perez
DISEASES OF THE COLON & RECTUM
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Najim El Khababi, Regina G. H. Beets-Tan, Renaud Tissier, Max J. Lahaye, Monique Maas, Luis Curvo-Semedo, Raphaela C. Dresen, Joost J. M. van Griethuysen, Stephanie Nougaret, Geerard L. Beets, Baukelien van Triest, Stuart A. Taylor, Doenja M. J. Lambregts
Summary: This study aims to explore the potential impact of a dedicated virtual training course on MRI staging confidence and performance in rectal cancer. The results show that although most of the findings are not statistically significant, there is a mild increase in diagnostic accuracy for most staging variables after completing the course, ranging from +2% to +17%. There is also an improvement in interobserver agreement for almost all variables when comparing the pre- and post-course. The perceived difficulty level decreases significantly after completion of the course, indicating an improved diagnostic confidence.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Najim El Khababi, Regina G. H. A. Beets-Tan, Renaud M. Tissier, Max Lahaye, Monique W. Maas, Luis Curvo-Semedo, Raphaela C. J. Dresen, Stephanie Nougaret, Geerard Beets, Doenja M. J. Lambregts
Summary: This study compared four previously published methods for evaluating rectal tumor response after chemoradiotherapy on MRI. The methods included T2W-MRI and DWI. The results showed that methods incorporating DWI had the most favorable outcomes in terms of diagnostic performance, interobserver agreement, and reader preference. Reader experience and image quality clearly affected diagnostic performance.
EUROPEAN RADIOLOGY
(2023)