Structures of membrane proteins

New insights into structure-function relationships between archeal ATP synthase (A1A0) and vacuolar type ATPase (V1V0)

(2009) Gerhard Grüber et al.   BIOESSAYS

Structure and function of Na+-symporters with inverted repeats

(2009) Jeff Abramson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Dynamic nature of disulphide bond formation catalysts revealed by crystal structures of DsbB

(2009) Kenji Inaba et al.   EMBO JOURNAL

Structure of thec14Rotor Ring of the Proton Translocating Chloroplast ATP Synthase

(2009) Melanie Vollmar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Location of the Retinal Chromophore in the Activated State of Rhodopsin*

(2009) Shivani Ahuja et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

State-stabilizing Interactions in Bacterial Mechanosensitive Channel Gating and Adaptation

(2009) Andriy Anishkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-electron Microscopy of the Vacuolar ATPase Motor Reveals its Mechanical and Regulatory Complexity

(2009) Stephen P. Muench et al.   JOURNAL OF MOLECULAR BIOLOGY

Thermostabilization of the Neurotensin Receptor NTS1

(2009) Yoko Shibata et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural insights into nonribosomal peptide enzymatic assembly lines

(2009) Alexander Koglin et al.   NATURAL PRODUCT REPORTS

Transport mechanism of a bacterial homologue of glutamate transporters

(2009) Nicolas Reyes et al.   NATURE

Crystal structure of the sodium–potassium pump at 2.4 Å resolution

(2009) Takehiro Shinoda et al.   NATURE

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

(2009) Eric B. Gonzales et al.   NATURE

Structure of a tetrameric MscL in an expanded intermediate state

(2009) Zhenfeng Liu et al.   NATURE

Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel

(2009) Yi Wang et al.   NATURE

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

Molecular basis of transport and regulation in the Na+/betaine symporter BetP

(2009) Susanne Ressl et al.   NATURE

The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism

(2009) Marcus Mueller et al.   NATURE

Structure of the connexin 26 gap junction channel at 3.5 Å resolution

(2009) Shoji Maeda et al.   NATURE

High-resolution structure of the rotor ring of a proton-dependent ATP synthase

(2009) Denys Pogoryelov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore

(2009) D. Stoddart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation

(2009) M. Quick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex

(2009) S. Krieg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A peroxide bridge between Fe and Cu ions in the O2 reduction site of fully oxidized cytochrome c oxidase could suppress the proton pump

(2009) H. Aoyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution Nuclear Magnetic Resonance Structure of Membrane-Integral Diacylglycerol Kinase

(2009) W. D. Van Horn et al.   SCIENCE

Structure and Mechanism of an Amino Acid Antiporter

(2009) X. Gao et al.   SCIENCE

Structure and Mechanism of a Na+-Independent Amino Acid Transporter

(2009) P. L. Shaffer et al.   SCIENCE

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Crystal Structure of a Yeast Aquaporin at 1.15 Å Reveals a Novel Gating Mechanism

(2009) Gerhard Fischer et al.   PLOS BIOLOGY

Solution-State NMR Spectroscopy of a Seven-Helix Transmembrane Protein Receptor: Backbone Assignment, Secondary Structure, and Dynamics

(2008) Antoine Gautier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unique Rotary ATP Synthase and Its Biological Diversity

(2008) Christoph von Ballmoos et al.   Annual Review of Biophysics

Rhomboid Proteases and their Biological Functions

(2008) Matthew Freeman   Annual Review of Genetics

Structural aspects of ion pumping by Ca2+-ATPase of sarcoplasmic reticulum

(2008) Chikashi Toyoshima   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The rotary mechanism of the ATP synthase

(2008) Robert K. Nakamoto et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Function, structure and regulation of the vacuolar (H+)-ATPases

(2008) Kevin C. Jefferies et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Chemical and NADH-Induced, ROS-Dependent, Cross-Linking between Subunits of Complex I fromEscherichia coliandThermus thermophilus†

(2008) John M. Berrisford et al.   BIOCHEMISTRY

The ADP and ATP transport in mitochondria and its carrier

(2008) Martin Klingenberg   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pore formation: An ancient yet complex form of attack

(2008) Ioan Iacovache et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Thirty years of protein translocation into mitochondria: Unexpectedly complex and still puzzling

(2008) Dejana Mokranjac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Fiber Formation across the Bacterial Outer Membrane by the Chaperone/Usher Pathway

(2008) Han Remaut et al.   CELL

Large-scale production of functional membrane proteins

(2008) F. Junge et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Type VI secretion: a beginner's guide

(2008) Lewis EH Bingle et al.   CURRENT OPINION IN MICROBIOLOGY

Catalysis within the lipid bilayer—structure and mechanism of the MAPEG family of integral membrane proteins

(2008) D MARTINEZMOLINA et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Overcoming the challenges of membrane protein crystallography

(2008) Elisabeth P Carpenter et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crystal structures of the OmpF porin: function in a colicin translocon

(2008) Eiki Yamashita et al.   EMBO JOURNAL

An intermediate step in the evolution of ATPases - a hybrid F0-V0 rotor in a bacterial Na+ F1F0 ATP synthase

(2008) Michael Fritz et al.   FEBS Journal

Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB

(2008) Goran Malojčić et al.   FEBS LETTERS

Cytochrome c oxidase: exciting progress and remaining mysteries

(2008) Peter Brzezinski et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Probing Structure-Function Relationships and Gating Mechanisms in the CorA Mg2+Transport System

(2008) Jian Payandeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of a Major Outer Membrane Protein from Thermus thermophilus HB27

(2008) Alexander Brosig et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformations of NhaA, the Na/H Exchanger from Escherichia coli, in the pH-Activated and Ion-Translocating States

(2008) Matthias Appel et al.   JOURNAL OF MOLECULAR BIOLOGY

NMR Solution Structure of the Integral Membrane Enzyme DsbB: Functional Insights into DsbB-Catalyzed Disulfide Bond Formation

(2008) Yunpeng Zhou et al.   MOLECULAR CELL

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Crystal structure of opsin in its G-protein-interacting conformation

(2008) Patrick Scheerer et al.   NATURE

Structure and mechanism of the M2 proton channel of influenza A virus

(2008) Jason R. Schnell et al.   NATURE

Crystal structure of squid rhodopsin

(2008) Midori Murakami et al.   NATURE

Structural basis for the function and inhibition of an influenza virus proton channel

(2008) Amanda L. Stouffer et al.   NATURE

Crystal structure of the ligand-free G-protein-coupled receptor opsin

(2008) Jung Hee Park et al.   NATURE

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

Structure of a complex of the ATPase SecA and the protein-translocation channel

(2008) Jochen Zimmer et al.   NATURE

Conformational transition of Sec machinery inferred from bacterial SecYE structures

(2008) Tomoya Tsukazaki et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Coupling ion channels to receptors for biomolecule sensing

(2008) Christophe J. Moreau et al.   Nature Nanotechnology

Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum

(2008) Zachary E R Newby et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular mechanism of energy conservation in polysulfide respiration

(2008) Mika Jormakka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Peering into an ATPase ion pump with single-channel recordings

(2008) D. C Gadsby et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel

(2008) G. M. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for induced formation of the inflammatory mediator prostaglandin E2

(2008) C. Jegerschold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced translocation of single DNA molecules through  -hemolysin nanopores by manipulation of internal charge

(2008) G. Maglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor

(2008) F. Magnani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational thermostabilization of the  1-adrenergic receptor in a detergent-resistant form

(2008) M. J. Serrano-Vega et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the human voltage-dependent anion channel

(2008) M. Bayrhuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

(2008) C. Altenbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

(2008) R. Ujwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mg2+-sensing mechanism of Mg2+ transporter MgtE probed by molecular dynamics study

(2008) R. Ishitani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution x-ray structure of human aquaporin 5

(2008) R. Horsefield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism

(2008) J. I. Yeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of an Open Form of an E. coli Mechanosensitive Channel at 3.45 A Resolution

(2008) W. Wang et al.   SCIENCE

A Structural Mechanism for MscS Gating in Lipid Bilayers

(2008) V. Vasquez et al.   SCIENCE

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

(2008) S. Hiller et al.   SCIENCE

Structural Basis of Trans-Inhibition in a Molybdate/Tungstate ABC Transporter

(2008) S. Gerber et al.   SCIENCE

Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter

(2008) S. Weyand et al.   SCIENCE

The High-Affinity E. coli Methionine ABC Transporter: Structure and Allosteric Regulation

(2008) N. S. Kadaba et al.   SCIENCE

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

(2008) S. Faham et al.   SCIENCE

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE

Single Copies of Sec61 and TRAP Associate with a Nontranslating Mammalian Ribosome

(2008) Jean-François Ménétret et al.   STRUCTURE

Disparate proteins use similar architectures to damage membranes

(2008) Gregor Anderluh et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure and mechanisms of the DsbB–DsbA disulfide bond generation machine

(2007) Kenji Inaba et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Crystal Structure of a Bacterial Signal Peptide Peptidase

(2007) Apollos C. Kim et al.   JOURNAL OF MOLECULAR BIOLOGY