期刊
PURE AND APPLIED CHEMISTRY
卷 82, 期 11, 页码 1975-1991出版社
WALTER DE GRUYTER GMBH
DOI: 10.1351/PAC-CON-09-12-15
关键词
alkaloids; iron; myosin; palladium; silver
We have developed efficient synthetic routes to heterocyclic ring systems using transition metals (palladium, iron, and silver). Recent applications of this chemistry to the total synthesis of biologically active alkaloids include carbazole alkaloids (pityriazole, euchrestifoline, the antiostatins), crispine A, pentabromo- and pentachloropseudilin. The two latter alkaloids represent a novel class of myosin ATPase inhibitors that led to the discovery of a new allosteric binding site of the protein.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据