On the role of aromatic-sugar interactions in the molecular recognition of carbohydrates:: A 3D view by using NMR

This revision describes an up-to-date review of our efforts to investigate the interaction of carbohydrates with aromatic moieties at different levels of complexity. Protein-Sugar interactions have been studied using NMR experiments oil a variety of hevein/chitooligosaccharide systems. In addition, NMR and computational methods have also been used to evaluate the interaction of simple aromatic entities with simple monosaccharides. In between, the stacking features of aromatic-containing -glycomolecules have also been described by using an analogous experimental-theoretical approach.