Article
Endocrinology & Metabolism
Suman Baral, Satyan Rajbhandari
Summary: Nepal, a developing country, is facing a major health challenge with a high prevalence of diabetes (8.5%) affecting around 2 million people. Limited resources pose barriers to providing affordable and convenient diabetes care or regular screening for complications. There is no reliable data on the incidence, prevalence, and complications of diabetic foot problems in Nepal.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Dermatology
Jennie E. Hancox, Charlotte Hilton, Katie Gray, Fran Game, Kavita Vedhara
Summary: Patients with diabetic foot ulcers often do not adhere to the advice of limiting weight-bearing activity, which is necessary for ulcers to heal. Communication of the advice, including rapport, empathy, and rationale, as well as individual factors such as daily demands, exercise enjoyment, and health benefits, influence patients' adherence. Healthcare professionals should employ a more person-centred approach tailored to patients' specific needs and consider patient priorities and constraints.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Medicine, General & Internal
Angel Ortiz-Zuniga, Jordi Samaniego, Betina Biagetti, Nicolas Allegue, Anna Gene, Andrea Sallent, Almudena Crespo, Jordi Serracanta, Carme Torrents, Daniela Issa, Danilo Rivas, Maria Teresa Veintemillas, Nuria Fernandez-Hidalgo, Rosa Busquets, Josep Royo, Cristina Hernandez
Summary: The aim of this study was to compare the incidence of lower-extremity amputations (LEA-DFD) before and after the establishment of a Diabetic Foot Multidisciplinary Unit. The results showed a significant reduction in the rate of amputations due to foot disease in patients with diabetes after the establishment of the unit.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Health Care Sciences & Services
Alvaro Astasio-Picado, Alba angel Babiano, Miriam Lopez-Sanchez, Rocio Ruiz Lozano, Paula Cobos-Moreno, Beatriz Gomez-Martin
Summary: This article provides evidence on the effectiveness and safety of ozone therapy in the treatment of wounds in patients with diabetic foot. It compares ozone therapy with other treatment methods and presents the findings of a literature review.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Sohail Akhtar, Mujahid Latif, Omer Shabbir Ahmed, Aqsa Sarwar, Ayisham Alina, Muhammad Imran Khan
Summary: This study explores the prevalence of foot ulcers among diabetic patients in Punjab, Pakistan and identifies associated factors. The results indicate a relatively high prevalence of foot ulcers in Punjab, highlighting the need for better strategies and preventive measures to address this epidemic.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Dermatology
Mohamed S. Imam, Ahmed Khalid Almutairi, Abdullah Mutrik Alhajri, Mishary Mosleh Alharby, Mohammed H. Alanazi, Ahmad G. Alotaibi, Mohamed E. A. Abdelrahim
Summary: This meta-analysis aimed to assess the effect of hyperbaric oxygen treatment on diabetic foot ulcers. The results showed that hyperbaric oxygen treatment had significantly higher rates of healed ulcers, adverse events, and ulcer area reduction, as well as lower mortality, compared to standard treatment. However, there was no significant difference in amputation and healing time between the two treatments. It is important to note that the selected studies had small sample sizes and limited comparisons.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Medicine, General & Internal
Sujit Kumar Das, Pinki Roy, Prabhishek Singh, Manoj Diwakar, Vijendra Singh, Ankur Maurya, Sandeep Kumar, Seifedine Kadry, Jungeun Kim
Summary: Diabetes is a chronic condition caused by uncontrolled blood sugar levels, and early diagnosis of complications such as diabetic foot ulcers (DFUs) can help prevent severe consequences. The use of deep learning, machine learning, and computer vision techniques provides promising solutions for assisting clinicians in diagnosing DFUs. This article provides a comprehensive overview of the current status of automatic DFU identification and highlights the dominance of CNN-based solutions in the field. It emphasizes the importance of combining traditional ML and advanced DL techniques for more reliable and efficient diagnostic decisions.
Review
Medicine, Research & Experimental
Yujia Zhang, Jing Zhang, Zhou Xu, Deju Zhang, Panpan Xia, Jitao Ling, Xiaoyi Tang, Xiao Liu, Rui Xuan, Meiying Zhang, Jianping Liu, Peng Yu
Summary: Non-coding RNA (ncRNA) is a significant component of the human genome, controlling various biological processes. It plays a crucial role in the onset and development of diabetes-related complications, such as diabetic foot ulcer (DFU). Understanding the mechanism and progress of ncRNA-protein binding in DFU can contribute to the early diagnosis and targeted intervention of DFU.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Nursing
Qi Qin, Makoto Oe, Gojiro Nakagami, Kosuke Kashiwabara, Junko Sugama, Hiromi Sanada, Suriadi Jais
Summary: The study investigated the effectiveness of nurse-led foot care guided by thermographic evaluation in preventing diabetic foot ulcer recurrence. The results showed that the intervention group had a significantly lower recurrence rate and improved foot care behavior compared to the control group. Therefore, regular foot care and personalized education can effectively reduce the recurrence of diabetic foot ulcers and improve quality of life and foot care behaviors.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2023)
Article
Medicine, General & Internal
Wei Chai, Yuqing Wang, Huancheng Zheng, Song Yue, Yan Liu, Yili Wu, Xuezhi Li
Summary: The study analyzed the pathogen spectrum and antibiotic susceptibility of diabetic foot ulcers, finding that dominant pathogens were sensitive to at least one antibiotic, but the antibacterial efficacy of common antibiotics decreased over time. Identification and testing of antibiotic susceptibility of dominant pathogens are essential for effective treatment of diabetic foot ulcers.
FRONTIERS IN MEDICINE
(2021)
Article
Dermatology
Deborah Christensen, Albert Botchway
Summary: A retrospective chart cohort review over 3 years shows that using a felt foot plate can effectively heal a diabetic foot ulcer, and patient weight and growth factors do not affect healing times.
ADVANCES IN SKIN & WOUND CARE
(2023)
Article
Dermatology
Liu He, Ya-Qing Xia, Cai-Feng Yang, Jia-Li He, Xian-Yu Tang
Summary: A meta-analysis was conducted to evaluate the management of diabetic foot wound ulcers (DFWUs) using laser therapy (LT). The results showed that LT had a significant effect on reducing ulcer size and promoting complete healing in individuals with DFWUs compared to control. However, caution should be exercised in interpreting the results due to the small sample size of the selected studies.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Medicine, General & Internal
Jean-Baptiste Bonnet, Ariane Sultan
Summary: The diabetic foot ulcer (DFU), a common and serious complication of diabetes, is influenced by the individual's social environment and access to healthcare. Financial insecurity and social protection systems play a significant role in DFU prognosis, while the relationship between socioeconomic and socio-educational deprivations and DFU is more complex. Understanding the correlation between DFU risk and social deprivation depends on how social deprivation is calculated and how questions about the relationship are framed.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Dermatology
Li Zhang, Guifen Fu, Yongqing Deng, Yuechou Nong, Jianhao Huang, Xiulu Huang, Fenglian Wei, Yanqing Yu, Litian Huang, Wenjiao Zhang, Meizhu Tang, Licai Deng, Jiaxia Han, Xing Zhou, Qiu Wang, Wensheng Lu
Summary: This study identified urine albumin-creatinine ratio (UACR) and vibration perception threshold (VPT) as independent risk factors for foot ulcer recurrence in patients with comorbid diabetic foot osteomyelitis and diabetic nephropathy. The study also suggested that microcirculation disorders play a major role in the recurrence of foot ulcer in these patients.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Infectious Diseases
Ines D. Teixeira, Eugenia Carvalho, Ermelindo C. Leal
Summary: Diabetic foot ulcers (DFU) are a serious complication of diabetes, affecting approximately 15% of patients and leading to lower limb amputations. However, impaired healing process and antimicrobial resistance pose challenges to effective treatment. This review explores the use of antimicrobial peptides derived from environmentally friendly processes as potential therapeutic compounds for DFUs, offering better quality of life to patients while preserving bio-resources.
Article
Endocrinology & Metabolism
Rita Forde, Liga Arente, Davide Ausili, Kristin De Backer, Mette Due-Christensen, Amanda Epps, Anne Fitzpatrick, Moira Grixti, Sijda Groen, Arja Halkoaho, Claudia Huber, Marjolein M. Iversen, Unn-Britt Johansson, Claudia Leippert, Seyda Ozcan, Julie Parker, Ana Christina Paiva, Adina Sanpetreanu, Marie-Alice Savet, Svetic-Cisic Rosana, Alicja Szewczyk, Maite Valverde, Eugenia Vlachou, Angus Forbes
Summary: The survey conducted on 1829 diabetes nurses across Europe revealed that the COVID-19 pandemic has significantly impacted the physical and psychological well-being of people with diabetes. Clinical problems such as anxiety, depression, and foot complications have increased, while the level of care provided and support services have declined during the pandemic.
Article
Psychology, Clinical
M. M. Iversen, T. M. Norekval, K. Oterhals, L. T. Fadnes, S. Maeland, A. H. Pakpour, K. Breivik
Summary: The research examined the psychometric properties of the Norwegian version of the FCV-19S in adults, revealing good internal consistency and an underlying two-factor structure (cognitive and somatic fear), supporting the use of total scores to measure fear of COVID-19.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2022)
Review
Endocrinology & Metabolism
Magdalena Beran, Rutendo Muzambi, Anouk Geraets, Juan Rafael Albertorio-Diaz, Marcel C. Adriaanse, Marjolein M. Iversen, Andrzej Kokoszka, Giesje Nefs, Arie Nouwen, Frans Pouwer, Jorg W. Huber, Andreas Schmitt, Miranda T. Schram
Summary: The study found a bidirectional longitudinal association between depressive symptoms and HbA(1c), with small effect sizes observed. Future research in large-scale longitudinal studies is needed to confirm this association. Future studies should investigate the role of diabetes type, depression, diabetes distress, and diabetes self-management behaviors.
Article
Endocrinology & Metabolism
Vera Vik Bjarko, Eirin B. Haug, Min P. Sorgjerd, Lars C. Stene, Paz Lopez-Doriga Ruiz, Kare Birkeland, Tore Julsrud Berg, Hanne Lovdal Gulseth, Marjolein M. Iversen, Arnulf Langhammer, Bjorn Olav Asvold
Summary: This study investigated the prevalence of undiagnosed diabetes and prediabetes and their association with cardiovascular risk factors. The results showed that individuals with undiagnosed diabetes had a poorer cardiovascular risk profile compared to those with known diabetes or no diabetes. The prevalence of undiagnosed diabetes was found to be low.
Article
Health Care Sciences & Services
John Roger Andersen, Kyrre Breivik, Inger Elise Engelund, Marjolein M. Iversen, Jorunn Kirkeleit, Tone Merete Norekval, Kjersti Oterhals, Anette Storesund
Summary: This study investigated the criterion validity and convergent validity of unweighted composite scores for physical and mental health. The results showed that these scores demonstrated satisfactory validity, suggesting that the calculation of these composite scores can be kept simple.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2022)
Article
Medicine, General & Internal
Hilde Kristin Refvik Riise, Jannicke Igland, Gerhard Sulo, Marjolein Memelink Iversen, Marit Graue, Anne Eskild, Grethe Seppola Tell, Anne Kjersti Daltveit
Summary: Women with pre-eclampsia have an increased risk of cardiovascular disease (HR 2.16), especially when accompanied by a large for gestational age offspring (HR 2.57). Diabetes during pregnancy also increases the risk of CVD, but it is not affected by offspring weight.
Article
Medicine, General & Internal
Rachel B. Forster, Ragnhild B. Strandberg, Katrina Louise Bo Tibballs, Kjersti Nokleby, Tore Julsrud Berg, Tor Iversen, Terje P. Hagen, Kare Ronn Richardsen, John Cooper, Sverre Sandberg, Karianne Fjeld Lovaas, Roy Miodini Nilsen, Marjolein Memelink Iversen, Anne Karen Jenum, Esben Selmer Selmer Buhl
Summary: The 'Outcomes & Multi-morbidity in Type 2 Diabetes' (OMIT) is an observational registry-based cohort study conducted in Norway to investigate high-risk groups often overlooked in randomized clinical trials of type 2 diabetes (T2D). The study cohort includes a large sample of T2D patients with diverse characteristics, and their clinical data are linked to various databases for comprehensive analysis. The findings provide valuable insights into the demographics, disease management, and prevalence of complications among T2D patients in Norway.
Article
Medicine, General & Internal
Karin Pleym, Marjolein Memelink Iversen, Anders Brostrom
Summary: This study describes the experiences and coping strategies of adults with type 1 diabetes during the COVID-19 pandemic in Norway. The findings show that patients experienced increased psychosocial burden and disruptions in daily life, which affected their self-management of T1DM. Despite these challenges, tailored information, telephone or video follow-ups were highlighted as important in reducing uncertainty distress and supporting adequate diabetes self-management.
Article
Environmental Sciences
Oscar Lecuona, Chung-Ying Lin, Dmitri Rozgonjuk, Tone M. Norekval, Marjolein M. Iversen, Mohammed A. Mamun, Mark D. Griffiths, Ting- Lin, Amir H. Pakpour
Summary: This study used network analysis to investigate the factor structure of the FCV-19S and identified a two-factor structure pattern involving physical and psychosocial factors. This pattern was consistent across gender, age groups, and countries.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Health Care Sciences & Services
Michael Quan Nguyen, Ingvild Dalen, Marjolein Memelink Iversen, Knut Harboe, Aksel Paulsen
Summary: This systematic review assesses the evidence for the measurement properties of patient-reported outcome measures (PROMs) used in the evaluation of adult patients with ankle fractures. The study found a lack of validation studies covering all measurement properties, preventing the recommendation of a specific PROM for this population.
QUALITY OF LIFE RESEARCH
(2023)
Article
Endocrinology & Metabolism
Tonje Teigland, Jannicke Igland, Grethe S. Tell, Johannes Haltbakk, Marit Graue, Anne-Siri Fismen, Kare I. Birkeland, Truls ostbye, Mark Peyrot, Marjolein M. Iversen
Summary: The study aims to estimate the prevalence, incidence, and time trends of pharmacologically treated diabetes among older people receiving home care services (HCS) in Norway from 2009 to 2014. The findings show an increasing prevalence of diabetes among older people receiving HCS, highlighting the importance of treatment and care related to diabetes in home care settings.
BMC ENDOCRINE DISORDERS
(2022)
Article
Nursing
Tone Nygaard Flolo, Kari Hanne Gjeilo, John Roger Andersen, Kristin Haraldstad, Inger Helene Hardeland Hjelmeland, Marjolein Memelink Iversen, Borghild Loyland, Tone Merete Norekval, Kirsti Riiser, Gudrun Rohde, Kristin Hjortland Urstad, Inger Utne, Elisabeth Grov Beisland
Summary: This study examined the satisfaction and quality concerns of baccalaureate nursing students in Norway with their educational curriculum, and found that these factors were associated with psychological distress and overall quality of life. However, concerns about clinical training had little impact on these associations.
Article
Endocrinology & Metabolism
Anne Karin Molvaer, Marjolein M. M. Iversen, Jannicke Igland, Mark Peyrot, Grethe S. S. Tell, Kristine Bech Holte, Vincent M. M. Monnier, Ingebjorg Seljeflot, Tore Julsrud Berg
Summary: This study examines the associations between metabolic parameters and pain, fatigue, depression, and quality of life in long-term type 1 diabetes patients. The results suggest that long-term chronic hyperglycemia may have a negative influence on pain and fatigue.
Article
Public, Environmental & Occupational Health
Ragnhild B. Strandberg, Roy M. Nilsen, Frans Pouwer, Jannicke Igland, Rachel B. Forster, Anne Karen Jenum, Esben S. Buhl, Marjolein M. Iversen
Summary: This study assessed the proportion of diabetes educational program participation among adults with type 2 diabetes mellitus (T2DM) in Norway, and its associations with place of residence, education, and immigrant background. The results showed that overall participation rate was 18%, with variations among different Norwegian counties. Individuals with immigrant background and lower education level were less likely to participate. Therefore, more efforts are needed to promote diabetes educational programs among patients with T2DM.
PATIENT EDUCATION AND COUNSELING
(2023)
Article
Medicine, General & Internal
Astrid Melteig Stalheim, Marjolein Memelink Iversen, Anne Karen Jenum, Line Sletner, Signe N. Stafne, Elisabeth Qvigstad, Linda Sagedal, Roy Miodini Nilsen, Vigdis Aasheim, Ragnhild B. Strandberg
Summary: This study used national population-based data from Norway and community-based data to analyze the association between maternal background and the season of pregnancy onset with the incidence of gestational diabetes mellitus (GDM). The results showed that there is a significant correlation between the season of pregnancy onset and the incidence of GDM in both Norwegian-born and immigrant women. Women with European ancestry had the highest incidence of GDM when pregnancy started in autumn and winter, while ethnic African and Asian women had the highest incidence when pregnancy onset was in summer.