标题
Pregnenolone sulfate as a modulator of synaptic plasticity
作者
关键词
Neurosteroid, NMDA receptor, Schizophrenia, GABA receptor
出版物
PSYCHOPHARMACOLOGY
Volume 231, Issue 17, Pages 3537-3556
出版商
Springer Nature
发表日期
2014-07-05
DOI
10.1007/s00213-014-3643-x
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Pregnenolone sulfate infused in lateral septum of male rats impairs novel object recognition memory
- (2014) Federico Nanfaro et al. Pharmacological Reports
- Pregnenolone Can Protect the Brain from Cannabis Intoxication
- (2014) Monique Vallée et al. SCIENCE
- Pregnenolone Sulfate Restores the Glutamate-Nitric-Oxide-cGMP Pathway and Extracellular GABA in Cerebellum and Learning and Motor Coordination in Hyperammonemic Rats
- (2013) Alba Gonzalez-Usano et al. ACS Chemical Neuroscience
- Pregnenolone sulphate enhances spatial orientation and object discrimination in adult male rats: Evidence from a behavioural and electrophysiological study
- (2013) Fulvio Plescia et al. BEHAVIOURAL BRAIN RESEARCH
- Glutamate-Based Antidepressants: Preclinical Psychopharmacology
- (2013) Andrzej Pilc et al. BIOLOGICAL PSYCHIATRY
- Pregnenolone sulfate modulates glycinergic transmission in rat medullary dorsal horn neurons
- (2013) Jung-Su Hong et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Simultaneous determination of pregnenolone sulphate, dehydroepiandrosterone and allopregnanolone in rat brain areas by liquid chromatography–electrospray tandem mass spectrometry
- (2013) Cecilia Rustichelli et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate Receptors
- (2013) S. M. Paul et al. JOURNAL OF NEUROSCIENCE
- Pregnenolone Sulfate: From Steroid Metabolite to TRP Channel Ligand
- (2013) Christian Harteneck MOLECULES
- Comparison of plasma and cerebrospinal fluid levels of neuroactive steroids with their brain, spinal cord and peripheral nerve levels in male and female rats
- (2013) Donatella Caruso et al. PSYCHONEUROENDOCRINOLOGY
- Neurosteroid PREGS Protects Neurite Growth and Survival of Newborn Neurons in the Hippocampal Dentate Gyrus of APPswe/PS1dE9 Mice
- (2012) Bingzhong Xu et al. Current Alzheimer Research
- Modulation by pregnenolone sulfate of filtering properties in the hippocampal trisynaptic circuit
- (2012) Chessa S. Scullin et al. HIPPOCAMPUS
- Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA- or sigma receptors in cerebellumin vivo
- (2012) Alba González-Usano et al. JOURNAL OF NEUROCHEMISTRY
- Inhibition by Pregnenolone Sulphate, a Metabolite of the Neurosteroid Pregnenolone, of Voltage-Gated Sodium Channels Expressed in Xenopus Oocytes
- (2012) Takafumi Horishita et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Determination of steroid metabolome as a possible tool for laboratory diagnosis of schizophrenia
- (2012) Marie Bicikova et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Pregnenolone sulfate decreases intraocular pressure and changes expression of sigma receptor in a model of chronic ocular hypertension
- (2012) Xian Sun et al. MOLECULAR BIOLOGY REPORTS
- The effect of the steroid sulfatase inhibitor (p-O-sulfamoyl)-tetradecanoyl tyramine (DU-14) on learning and memory in rats with selective lesion of septal–hippocampal cholinergic tract
- (2012) P.A. Babalola et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Anti-amnesic effect of neurosteroid PREGS in Aβ25–35-injected mice through σ1 receptor- and α7nAChR-mediated neuroprotection
- (2012) Rong Yang et al. NEUROPHARMACOLOGY
- Continuous de novo synthesis of neurosteroids is required for normal synaptic transmission and plasticity in the dentate gyrus of the rat hippocampus
- (2012) Motoki Tanaka et al. NEUROPHARMACOLOGY
- The NMDA receptor as a target for cognitive enhancement
- (2012) Graham L. Collingridge et al. NEUROPHARMACOLOGY
- Neurosteroids, stress and depression: Potential therapeutic opportunities
- (2012) Charles F. Zorumski et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Pregnenolone Rescues Schizophrenia-Like Behavior in Dopamine Transporter Knockout Mice
- (2012) Peiyan Wong et al. PLoS One
- Neurosteroid binding to the amino terminal and glutamate binding domains of ionotropic glutamate receptors
- (2012) Krasnodara Cameron et al. STEROIDS
- Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning
- (2011) Laura Mòdol et al. BEHAVIOURAL BRAIN RESEARCH
- Hydrophobic anions potently and uncompetitively antagonize GABAAreceptor function in the absence of a conventional binding site
- (2011) M Chisari et al. BRITISH JOURNAL OF PHARMACOLOGY
- Activation of steroid-sensitive TRPM3 channels potentiates glutamatergic transmission at cerebellar Purkinje neurons from developing rats
- (2011) Paula A. Zamudio-Bulcock et al. JOURNAL OF NEUROCHEMISTRY
- A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protons
- (2011) Emmanuel Kostakis et al. JOURNAL OF NEUROCHEMISTRY
- Pregnenolone Sulfate Activates Basic Region Leucine Zipper Transcription Factors in Insulinoma Cells: Role of Voltage-Gated Ca2+ Channels and Transient Receptor Potential Melastatin 3 Channels
- (2011) I. Muller et al. MOLECULAR PHARMACOLOGY
- Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors
- (2011) Martin Elfverson et al. NEUROPHARMACOLOGY
- Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo
- (2011) O. Cauli et al. NEUROSCIENCE
- Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence
- (2011) C.E. Marx et al. NEUROSCIENCE
- Allopregnanolone infused into the dorsal (CA1) hippocampus increases prepulse inhibition of startle response in Wistar rats
- (2011) Sònia Darbra et al. PSYCHONEUROENDOCRINOLOGY
- A history of depression in women is associated with an altered GABAergic neuroactive steroid profile
- (2011) Susan S. Girdler et al. PSYCHONEUROENDOCRINOLOGY
- Neurosteroid modulation of N-methyl-d-aspartate receptors: Molecular mechanism and behavioral effects
- (2011) Miloslav Korinek et al. STEROIDS
- Determination of Steroids and Their Intact Glucuronide Conjugates in Mouse Brain by Capillary Liquid Chromatography-Tandem Mass Spectrometry
- (2010) Sirkku E. Jäntti et al. ANALYTICAL CHEMISTRY
- Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour
- (2010) Sònia Darbra et al. BEHAVIOURAL BRAIN RESEARCH
- Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration
- (2010) Tobias Johansson et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects
- (2010) Jennifer C. Naylor et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- TRPM3 channel stimulated by pregnenolone sulphate in synovial fibroblasts and negatively coupled to hyaluronan
- (2010) Coziana Ciurtin et al. BMC MUSCULOSKELETAL DISORDERS
- Pregnenolone Sulphate- and Cholesterol-Regulated TRPM3 Channels Coupled to Vascular Smooth Muscle Secretion and Contraction
- (2010) Jacqueline Naylor et al. CIRCULATION RESEARCH
- Pregnenolone sulfate and its enantiomer: Differential modulation of memory in a spatial discrimination task using forebrain NMDA receptor deficient mice
- (2010) Géraldine H. Petit et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Pregnenolone Sulfate and Cortisol Induce Secretion of Acyl-CoA-binding Protein and Its Conversion into Endozepines from Astrocytes
- (2010) William F. Loomis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pregnenolone and Dehydroepiandrosterone as an Adjunctive Treatment in Schizophrenia and Schizoaffective Disorder
- (2010) Michael S. Ritsner et al. JOURNAL OF CLINICAL PSYCHIATRY
- TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes
- (2010) Anja Hoffmann et al. JOURNAL OF NEUROCHEMISTRY
- Neurosteroid transport by the organic solute transporter OSTα-OSTβ
- (2010) Fang Fang et al. JOURNAL OF NEUROCHEMISTRY
- Cognition Enhancement Strategies
- (2010) J. A. Bibb et al. JOURNAL OF NEUROSCIENCE
- Pregnenolone sulfate enhances survival of adult-generated hippocampal granule cells via sustained presynaptic potentiation
- (2010) Rong Yang et al. NEUROPHARMACOLOGY
- Pregnenolone sulfate enhances spontaneous glutamate release by inducing presynaptic Ca2+-induced Ca2+ release
- (2010) K.H. Lee et al. NEUROSCIENCE
- Pregnenolone sulfate increases glutamate release at neonatal climbing fiber-to-Purkinje cell synapses
- (2010) P.A. Zamudio-Bulcock et al. NEUROSCIENCE
- Multiple roles for the first transmembrane domain of GABAA receptor subunits in neurosteroid modulation and spontaneous channel activity
- (2010) Carrie Baker et al. NEUROSCIENCE LETTERS
- TRPM3 channels provide a regulated influx pathway for zinc in pancreatic beta cells
- (2010) Thomas F. J. Wagner et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Pregnenolone for cognition and mood in dual diagnosis patients
- (2010) I. Julian Osuji et al. PSYCHIATRY RESEARCH
- Glucocorticoid Dysregulations and Their Clinical Correlates
- (2009) Andrea H. Marques et al. Annals of the New York Academy of Sciences
- Minimizing the effects of multicollinearity in the polynomial regression of age relationships and sex differences in serum levels of pregnenolone sulfate in healthy subjects
- (2009) Milan Meloun et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Neurosteroid biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides
- (2009) Jean Luc Do Rego et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Analysis of pregnenolone and dehydroepiandrosterone in rodent brain: cholesterol autoxidation is the key
- (2009) Philippe Liere et al. JOURNAL OF LIPID RESEARCH
- Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: therapeutic implications
- (2009) Pablo A. Gaspar et al. JOURNAL OF NEUROCHEMISTRY
- Long-Term Potentiation in the Rat Medial Vestibular Nuclei Depends on Locally Synthesized 17 -Estradiol
- (2009) S. Grassi et al. JOURNAL OF NEUROSCIENCE
- Peripheral neuroactive steroids may be as good as the steroids in the cerebrospinal fluid for the diagnostics of CNS disturbances
- (2009) Radmila Kancheva et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The molecular and cellular biology of enhanced cognition
- (2009) Yong-Seok Lee et al. NATURE REVIEWS NEUROSCIENCE
- Proof-of-Concept Trial with the Neurosteroid Pregnenolone Targeting Cognitive and Negative Symptoms in Schizophrenia
- (2009) Christine E Marx et al. NEUROPSYCHOPHARMACOLOGY
- Pregnenolone sulfate modulation of N-methyl-d-aspartate receptors is phosphorylation dependent
- (2009) M. Petrovic et al. NEUROSCIENCE
- Pregnenolone Sulfate Potentiates the Inwardly Rectifying K+ Channel Kir2.3
- (2009) Toru Kobayashi et al. PLoS One
- Neuroactive steroid regulation of neurotransmitter release in the CNS: Action, mechanism and possible significance
- (2009) Ping Zheng PROGRESS IN NEUROBIOLOGY
- Simultaneous quantification of GABAergic 3α,5α/3α,5β neuroactive steroids in human and rat serum
- (2009) Patrizia Porcu et al. STEROIDS
- Neurosteroids allosterically modulate the ion pore of the NMDA receptor consisting of NR1/NR2B but not NR1/NR2A
- (2008) Martin Elfverson et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Pregnenolone protects the PC-12 cell line against amyloid beta peptide toxicity but its sulfate ester does not
- (2008) Pinar Akan et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Neurosteroids 3β, 20 (R/S)-pregnandiols decrease offset rate of the GABA-site activation at the recombinant GABAA receptor
- (2008) Ming-De Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum
- (2008) Matthew T. Whittaker et al. JOURNAL OF NEUROCHEMISTRY
- Steroid Receptor Signalling in the Brain - Lessons Learned from Molecular Imaging
- (2008) M. Kawata et al. JOURNAL OF NEUROENDOCRINOLOGY
- Nanomolar Concentrations of Pregnenolone Sulfate Enhance Striatal Dopamine Overflow in Vivo
- (2008) G. Sadri-Vakili et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Involvement of sigma (σ1) receptors in modulating the anti-depressant effect of neurosteroids (dehydroepiandrosterone or pregnenolone) in mouse tail-suspension test
- (2008) A. Dhir et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Mutations of the GABA-A Receptor 1 Subunit M1 Domain Reveal Unexpected Complexity for Modulation by Neuroactive Steroids
- (2008) G. Akk et al. MOLECULAR PHARMACOLOGY
- Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells
- (2008) Thomas F.J. Wagner et al. NATURE CELL BIOLOGY
- Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration
- (2008) E. Martín-García et al. NEUROSCIENCE
- The 3β-hydroxysteroid dehydrogenase inhibitor trilostane shows antidepressant properties in mice
- (2008) Julie Espallergues et al. PSYCHONEUROENDOCRINOLOGY
- A post-training intrahippocampal anxiogenic dose of the neurosteroid pregnenolone sulfate impairs passive avoidance retention
- (2008) E. Martín-García et al. EXPERIMENTAL BRAIN RESEARCH
- Modulation of glutamatergic transmission by sulfated steroids: Role in fetal alcohol spectrum disorder
- (2007) C. Fernando Valenzuela et al. BRAIN RESEARCH REVIEWS
- Emergence of NMDAR-independent long-term potentiation at hippocampal CA1 synapses following early adolescent exposure to chronic intermittent ethanol: Role for sigma-receptors
- (2007) Jilla Sabeti et al. HIPPOCAMPUS
- Pregnenolone sulfate in the brain: A controversial neurosteroid
- (2007) Michael Schumacher et al. NEUROCHEMISTRY INTERNATIONAL
- Regulation of SULT2B1a (pregnenolone sulfotransferase) expression in rat C6 glioma cells: Relevance of AMPA receptor-mediated NO signaling
- (2007) Atsushi Kohjitani et al. NEUROSCIENCE LETTERS
- Differential hypothalamic–pituitary–adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects
- (2007) Patrizia Porcu et al. PSYCHONEUROENDOCRINOLOGY
- Characterisation of N-Methyl-D-Aspartate Receptor-Specific [3H]Ifenprodil Binding to Recombinant Human NR1a/NR2B Receptors Compared with Native Receptors in Rodent Brain Membranes
- (2003) Sarah Grimwood et al. JOURNAL OF NEUROCHEMISTRY
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