Negative versus positive allosteric modulation of metabotropic glutamate receptors (mGluR5): indices for potential pro-cognitive drug properties based on EEG network oscillations and sleep-wake organization in rats

Cortical EEG oscillations and network connectivity as efficacy indices for assessing drugs with cognition enhancing potential

(2014) A. Ahnaou et al.   NEUROPHARMACOLOGY

Chronic Metabotropic Glutamate Receptor 5 Inhibition Corrects Local Alterations of Brain Activity and Improves Cognitive Performance in Fragile X Mice

(2013) Aubin Michalon et al.   BIOLOGICAL PSYCHIATRY

Dissociation between Dorsal and Ventral Hippocampal Theta Oscillations during Decision-Making

(2013) B. Schmidt et al.   JOURNAL OF NEUROSCIENCE

Prefrontal atrophy, disrupted NREM slow waves and impaired hippocampal-dependent memory in aging

(2013) Bryce A Mander et al.   NATURE NEUROSCIENCE

Sleep-dependent memory triage: evolving generalization through selective processing

(2013) Robert Stickgold et al.   NATURE NEUROSCIENCE

mGluR5 Ablation in Cortical Glutamatergic Neurons Increases Novelty-Induced Locomotion

(2013) Chris P. Jew et al.   PLoS One

Increased Metabotropic Glutamate Receptor Subtype 5 Availability in Human Brain After One Night Without Sleep

(2012) Katharina Hefti et al.   BIOLOGICAL PSYCHIATRY

Coherence, Phase Differences, Phase Shift, and Phase Lock in EEG/ERP Analyses

(2012) Robert W. Thatcher   DEVELOPMENTAL NEUROPSYCHOLOGY

The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments inFmr1KO mice

(2012) M. F. Vinueza Veloz et al.   GENES BRAIN AND BEHAVIOR

Memantine potentiates hippocampal theta oscillations at a therapeutic dose in anesthetized mice: A mechanistic link to its cognitive-enhancing properties

(2012) Simone Guadagna et al.   NEUROPHARMACOLOGY

In vitro characterisation of the novel positive allosteric modulators of the mGlu5 receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat

(2012) Gary Gilmour et al.   NEUROPHARMACOLOGY

Role of Homer Proteins in the Maintenance of Sleep-Wake States

(2012) Nirinjini Naidoo et al.   PLoS One

Effects of MPEP, a selective metabotropic glutamate mGlu5 ligand, on sleep and wakefulness in the rat

(2012) María Cavas et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Oscillations in the prefrontal cortex: a gateway to memory and attention

(2011) Karim Benchenane et al.   CURRENT OPINION IN NEUROBIOLOGY

Simultaneous real-time measurement of EEG/EMG and l-glutamate in mice: A biosensor study of neuronal activity during sleep

(2011) Erik Naylor et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

The cognitive cost of sleep lost

(2011) John G. McCoy et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Dynamic Formation of Functional Networks by Synchronization

(2011) Wolf Singer   NEURON

Metabotropic glutamate receptor subtype 5 antagonism in learning and memory

(2010) Agnes Simonyi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Shaping Functional Architecture by Oscillatory Alpha Activity: Gating by Inhibition

(2010) Ole Jensen et al.   Frontiers in Human Neuroscience

Differential effects of the mGluR5 positive allosteric modulator CDPPB in the cortex and striatum following repeated administration

(2010) Sophie Parmentier-Batteur et al.   NEUROPHARMACOLOGY

Studies on wakefulness-promoting effect of memantine in rats

(2009) Takayuki Ishida et al.   BEHAVIOURAL BRAIN RESEARCH

Spatio-temporal dynamics of theta oscillations in hippocampal-entorhinal slices

(2009) N.L.M. Cappaert et al.   HIPPOCAMPUS

A pilot open label, single dose trial of fenobam in adults with fragile X syndrome

(2009) E Berry-Kravis et al.   JOURNAL OF MEDICAL GENETICS

How to Keep the Brain Awake? The Complex Molecular Pharmacogenetics of Wake Promotion

(2009) Sibah Hasan et al.   NEUROPSYCHOPHARMACOLOGY

Human gamma-band activity: A review on cognitive and behavioral correlates and network models

(2009) Christoph S. Herrmann et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons

(2009) P. Wulff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The whats and whens of sleep-dependent memory consolidation

(2009) Susanne Diekelmann et al.   SLEEP MEDICINE REVIEWS

Modulation of group II metabotropic glutamate receptor (mGlu2) elicits common changes in rat and mice sleep–wake architecture

(2008) Abdellah Ahnaou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor up-regulation

(2008) Laura Gray et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Theta and Gamma Coordination of Hippocampal Networks during Waking and Rapid Eye Movement Sleep

(2008) S. M. Montgomery et al.   JOURNAL OF NEUROSCIENCE

ADX47273 [S-(4-Fluoro-phenyl)- -methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities

(2008) F. Liu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Theta synchronizes the activity of medial prefrontal neurons during learning

(2008) R. Paz et al.   LEARNING & MEMORY

Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant–anticonvulsant action

(2008) Ilse Smolders et al.   NEUROPHARMACOLOGY

Metabotropic Glutamate Receptors 5 Blockade Reverses Spatial Memory Deficits in a Mouse Model of Parkinson's Disease

(2008) Elvira De Leonibus et al.   NEUROPSYCHOPHARMACOLOGY

Spontaneous neural activity during human slow wave sleep

(2008) T. T. Dang-Vu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Neural Coding Scheme Formed by the Combined Function of Gamma and Theta Oscillations

(2008) J. Lisman et al.   SCHIZOPHRENIA BULLETIN