Reversal learning as a measure of impulsive and compulsive behavior in addictions

Animal models of prefrontal-executive function.

(2011) Yogita Chudasama   BEHAVIORAL NEUROSCIENCE

Response Perseveration in Stimulant Dependence Is Associated with Striatal Dysfunction and Can Be Ameliorated by a D2/3 Receptor Agonist

(2011) Karen D. Ersche et al.   BIOLOGICAL PSYCHIATRY

Genetic Dissection of Behavioral Flexibility: Reversal Learning in Mice

(2011) Rick E. Laughlin et al.   BIOLOGICAL PSYCHIATRY

Dorsal Striatal D2-Like Receptor Availability Covaries with Sensitivity to Positive Reinforcement during Discrimination Learning

(2011) S. M. Groman et al.   JOURNAL OF NEUROSCIENCE

Dopamine, But Not Serotonin, Regulates Reversal Learning in the Marmoset Caudate Nucleus

(2011) H. F. Clarke et al.   JOURNAL OF NEUROSCIENCE

Dissociable Effects of Subtotal Lesions within the Macaque Orbital Prefrontal Cortex on Reward-Guided Behavior

(2011) P. H. Rudebeck et al.   JOURNAL OF NEUROSCIENCE

Impulsivity, Compulsivity, and Top-Down Cognitive Control

(2011) Jeffrey W. Dalley et al.   NEURON

Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat

(2010) Samantha L. McLean et al.   BEHAVIOURAL BRAIN RESEARCH

Selective lesions of the dorsomedial striatum impair serial spatial reversal learning in rats

(2010) Anna Castañé et al.   BEHAVIOURAL BRAIN RESEARCH

Improved Reversal Learning and Working Memory and Enhanced Reactivity to Novelty in Mice with Enhanced GABAergic Innervation in the Dentate Gyrus

(2010) Fabio Morellini et al.   CEREBRAL CORTEX

Enhancement of Spatial Reversal Learning by 5-HT2C Receptor Antagonism Is Neuroanatomically Specific

(2010) V. Boulougouris et al.   JOURNAL OF NEUROSCIENCE

Morphological differences associated with a serotonin transporter polymorphism (5-HTTLPR) in rhesus macaques

(2010) H P Jedema et al.   MOLECULAR PSYCHIATRY

A selective role for dopamine in stimulus–reward learning

(2010) Shelly B. Flagel et al.   NATURE

Serotonin Modulates Sensitivity to Reward and Negative Feedback in a Probabilistic Reversal Learning Task in Rats

(2010) Andrea Bari et al.   NEUROPSYCHOPHARMACOLOGY

Brief exposure to methamphetamine (METH) and phencyclidine (PCP) during late development leads to long-term learning deficits in rats

(2009) Ilsun M. White et al.   BRAIN RESEARCH

Neural Components Underlying Behavioral Flexibility in Human Reversal Learning

(2009) D. G. Ghahremani et al.   CEREBRAL CORTEX

Pharmacological or Genetic Inactivation of the Serotonin Transporter Improves Reversal Learning in Mice

(2009) J. L. Brigman et al.   CEREBRAL CORTEX

Midbrain Dopamine Receptor Availability Is Inversely Associated with Novelty-Seeking Traits in Humans

(2009) D. H. Zald et al.   JOURNAL OF NEUROSCIENCE

Dopamine DRD2 Polymorphism Alters Reversal Learning and Associated Neural Activity

(2009) G. Jocham et al.   JOURNAL OF NEUROSCIENCE

Striatal Dopamine Predicts Outcome-Specific Reversal Learning and Its Sensitivity to Dopaminergic Drug Administration

(2009) R. Cools et al.   JOURNAL OF NEUROSCIENCE

Striatal Dopamine D2/D3 Receptor Availability Is Reduced in Methamphetamine Dependence and Is Linked to Impulsivity

(2009) B. Lee et al.   JOURNAL OF NEUROSCIENCE

Rat Prefrontal Cortical Neurons Selectively Code Strategy Switches

(2009) E. L. Rich et al.   JOURNAL OF NEUROSCIENCE

Effect of acute and repeated treatment with desipramine or methylphenidate on serial reversal learning in rats

(2009) Emanuele Seu et al.   NEUROPHARMACOLOGY

Executive cognitive functions and impulsivity as correlates of risk taking and problem behavior in preadolescents

(2009) Daniel Romer et al.   NEUROPSYCHOLOGIA

Probing Compulsive and Impulsive Behaviors, from Animal Models to Endophenotypes: A Narrative Review

(2009) Naomi A Fineberg et al.   NEUROPSYCHOPHARMACOLOGY

Reversal-Specific Learning Impairments After a Binge Regimen of Methamphetamine in Rats: Possible Involvement of Striatal Dopamine

(2009) Alicia Izquierdo et al.   NEUROPSYCHOPHARMACOLOGY

Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action

(2009) Bernard W Balleine et al.   NEUROPSYCHOPHARMACOLOGY

A role for dopamine D2 receptors in reversal learning

(2009) D.A. DeSteno et al.   NEUROSCIENCE

Impulsivity, frontal lobes and risk for addiction

(2009) Fulton Timm Crews et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Polymorphisms in the 3′ UTR of the serotonin transporter are associated with cognitive flexibility in rhesus macaques

(2008) Eric J. Vallender et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Inactivation of the medial prefrontal cortex of the rat impairs strategy set-shifting, but not reversal learning, using a novel, automated procedure

(2008) Stan B. Floresco et al.   BEHAVIOURAL BRAIN RESEARCH

Double Dissociation of the Effects of Medial and Orbital Prefrontal Cortical Lesions on Attentional and Affective Shifts in Mice

(2008) G. B. Bissonette et al.   JOURNAL OF NEUROSCIENCE

Lesions of the Medial Striatum in Monkeys Produce Perseverative Impairments during Reversal Learning Similar to Those Produced by Lesions of the Orbitofrontal Cortex

(2008) H. F. Clarke et al.   JOURNAL OF NEUROSCIENCE

Frontal Cortex Subregions Play Distinct Roles in Choices between Actions and Stimuli

(2008) P. H. Rudebeck et al.   JOURNAL OF NEUROSCIENCE

Amygdala and Orbitofrontal Cortex Lesions Differentially Influence Choices during Object Reversal Learning

(2008) P. H. Rudebeck et al.   JOURNAL OF NEUROSCIENCE

Impulsivity as a vulnerability marker for substance-use disorders: Review of findings from high-risk research, problem gamblers and genetic association studies

(2008) Antonio Verdejo-García et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Impulsivity is associated with behavioral decision-making deficits

(2008) Ingmar H.A. Franken et al.   PSYCHIATRY RESEARCH

Initial nicotine sensitivity in humans as a function of impulsivity

(2008) Kenneth A. Perkins et al.   PSYCHOPHARMACOLOGY

Dopamine D2/D3 receptor agonist quinpirole impairs spatial reversal learning in rats: investigation of D3 receptor involvement in persistent behavior

(2008) Vasileios Boulougouris et al.   PSYCHOPHARMACOLOGY

Inhibition of the norepinephrine transporter improves behavioral flexibility in rats and monkeys

(2008) Emanuele Seu et al.   PSYCHOPHARMACOLOGY

The neuropsychopharmacology of action inhibition: cross-species translation of the stop-signal and go/no-go tasks

(2008) Dawn M. Eagle et al.   PSYCHOPHARMACOLOGY

Chronic cocaine but not chronic amphetamine use is associated with perseverative responding in humans

(2008) Karen D. Ersche et al.   PSYCHOPHARMACOLOGY

Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats

(2008) M. Danet S. Lapiz-Bluhm et al.   PSYCHOPHARMACOLOGY

The role of impulsive behavior in drug abuse

(2008) Jennifer L. Perry et al.   PSYCHOPHARMACOLOGY

High Impulsivity Predicts the Switch to Compulsive Cocaine-Taking

(2008) D. Belin et al.   SCIENCE

Serial reversal learning and acute tryptophan depletion

(2007) Geoffrey van der Plasse et al.   BEHAVIOURAL BRAIN RESEARCH

The neurobiology and genetics of impulse control disorders: Relationships to drug addictions

(2007) Judson A. Brewer et al.   BIOCHEMICAL PHARMACOLOGY

The Role of Orbitofrontal Cortex in Drug Addiction: A Review of Preclinical Studies

(2007) Geoffrey Schoenbaum et al.   BIOLOGICAL PSYCHIATRY

Impulsive Choice and Impulsive Action Predict Vulnerability to Distinct Stages of Nicotine Seeking in Rats

(2007) Leontien Diergaarde et al.   BIOLOGICAL PSYCHIATRY

Differential effects of inactivation of the orbitofrontal cortex on strategy set-shifting and reversal learning

(2007) Sarvin Ghods-Sharifi et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Neurobehavioral mechanisms of impulsivity: Fronto-striatal systems and functional neurochemistry

(2007) Jeffrey W. Dalley et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR