Review
Biochemistry & Molecular Biology
Yuanliang Zhu, Dan Li, Yucheng Zhou, Yue Hu, Zhangyu Xu, Lei Lei, Fangyuan Xu, Jianxiong Wang
Summary: High-frequency repetitive transcranial magnetic stimulation (HF rTMS) on the dorsolateral prefrontal cortex (DLPFC) can relieve chronic pain and accompanying depressive symptoms, particularly showing significant analgesic effects in the mid-term and long-term.
ACS CHEMICAL NEUROSCIENCE
(2022)
Article
Neurosciences
Huan Wang, Yuzhong Hu, Jiayi Deng, Yang Ye, Manli Huang, Xianwei Che, Liang Yu
Summary: This study investigated the efficacy of repetitive transcranial magnetic stimulation (rTMS) on postherpetic neuralgia (PHN) by stimulating the motor cortex (M1) and the dorsolateral prefrontal cortex (DLPFC). The results showed that M1 stimulation was superior to DLPFC stimulation in reducing pain and improving sleep quality in PHN patients.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Behavioral Sciences
Hazel Zeynep Kurada, Elif Arica-Akkok, Zerin Ozaydin-Aksun, H. Ozden Sener, Michal Lavidor
Summary: The understanding of transparent idioms tends to involve more right hemisphere resources, while the processing of opaque idioms relies more on left hemisphere resources. Therefore, the transparency of idioms may play an important role in modulating hemispheric functions involved in figurative language processing.
Article
Neurosciences
Lin Zhu, Ge Dang, Wei Wu, Junhong Zhou, Xue Shi, Xiaolin Su, Huixia Ren, Zian Pei, Xiaoyong Lan, Chongyuan Lian, Peng Xie, Yi Guo
Summary: This study investigated the mechanisms underlying the efficacy of repetitive transcranial magnetic stimulation (rTMS) in chronic insomnia disorder (CID) and found that alterations in functional connectivity were associated with clinical outcomes. Specifically, rTMS treatment significantly increased connectivity in a specific frequency band and the changes in connectivity were related to improvement in insomnia symptoms. These findings provide preliminary evidence for prospective clinical trials and treatment optimization.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Neurosciences
Yang Ye, Jinghua Wang, Xianwei Che
Summary: This study used TMS-EEG to investigate the local and distributed neuroplastic changes associated with DLPFC analgesia. The findings suggest that DLPFC stimulation leads to a decrease in N120 amplitude in the contralateral prefrontal cortex and an increase in N120 peak in the ipsilateral insular cortex. There is also a negative correlation between N120 changes in these two regions, and the amplitude changes of this dyad are associated with increased pain threshold. Additionally, DLPFC stimulation enhances coherence between the prefrontal and somatosensory cortices oscillating in the gamma frequency.
Article
Neurosciences
Idris Fatakdawala, Hasan Ayaz, Adrian Safati, Mohammad Nazmus Sakib, Peter A. Hall
Summary: This study examined the effects of excitatory brain stimulation on eating behavior, and found that targeting the dorsolateral prefrontal cortex (dlPFC) and dorsomedial prefrontal cortex (dmPFC) had different effects. Stimulation of the dlPFC enhanced interference control, while stimulation of the dmPFC reduced delay discounting. Gender also moderated the effects during the taste test, with females in the dmPFC stimulation group showing paradoxical increases in food consumption.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2023)
Article
Psychiatry
Tong Yu, Wangni Chen, Lijuan Huo, Xin Luo, Jijun Wang, Bin Zhang
Summary: This study conducted a meta-analysis of sham-controlled trials on repetitive transcranial magnetic stimulation (rTMS) for depression and found that the number of pulses and sessions per day were significantly associated with efficacy, while positioning method, stimulation intensity, frequency, number of treatment days, and total pulses were not. Therefore, increasing the number of daily pulses and sessions may improve the effectiveness of rTMS in clinical practice.
PSYCHIATRY RESEARCH
(2023)
Review
Clinical Neurology
Xianwei Che, Robin F. H. Cash, Xi Luo, Hong Luo, Xiaodong Lu, Feng Xu, Yu-Feng Zang, Paul B. Fitzgerald, Bernadette M. Fitzgibbon
Summary: The study found that high-frequency rTMS stimulation of the DLPFC has significant short-term analgesic effects on neuropathic pain. There is also an overall pain reduction in the midterm and long term, as well as significant analgesic effect on provoked pain following HF-rTMS over the DLPFC.
Article
Medicine, General & Internal
Remi Moirand, Laetitia Imbert, Frederic Haesebaert, Gabrielle Chesnoy, Benoit Bediou, Emmanuel Poulet, Jerome Brunelin
Summary: This study investigated the clinical interest of a 10 session tDCS regimen in patients with mild to severe treatment-resistant depression. The results showed that bifrontal add-on tDCS, combined with antidepressant medication, can be a safe and suitable approach to achieve remission in these patients. However, further studies are needed to confirm these findings in a larger sample size.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Giuseppe Giglia, Giuditta Gambino, Luca Cuffaro, Fabio Aleo, Pierangelo Sardo, Giuseppe Ferraro, Valeria Blandino, Filippo Brighina, Massimo Gangitano, Tommaso Piccoli
Summary: Research showed that inhibitory rTMS on the right DLPFC can interfere with LTM memory performance during the late-encoding phase, with opposite effects at the pre-retrieval phase.
Article
Psychiatry
Ghina Harika-Germaneau, Issa Wassouf, Tom Le Tutour, Remy Guillevin, Damien Doolub, Reza Rostami, Alexia Delbreil, Nicolas Langbour, Nematollah Jaafari
Summary: This study explored the clinical and neuroimaging biomarkers associated with the responsiveness of patients with treatment-resistant depression (TRD) to high-frequency rTMS treatment over the left dorso-lateral pre-frontal cortex (DLPFC). The findings showed that women, patients with bipolar depressive disorder, and patients who are less resistant to rTMS tend to respond better. Furthermore, responders exhibited a lower volume in specific brain regions. These findings support further investigation into the use of clinical variables and structural MRI as potential biomarkers for rTMS treatment response.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Behavioral Sciences
Lysianne Beynel, Moritz Dannhauer, Hannah Palmer, Susan A. Hilbig, Courtney A. Crowell, Joyce E-H. Wang, Andrew M. Michael, Eleanor A. Wood, Bruce Luber, Sarah H. Lisanby, Angel V. Peterchev, Roberto Cabeza, Simon W. Davis, Lawrence G. Appelbaum
Summary: This study investigated the site-specific effects of rTMS on working memory subprocesses, specifically maintenance and manipulation, but did not find significant differences between active and sham stimulation conditions. However, exploratory analyses revealed some interesting trends related to stimulation amplitude and functional activation that may contribute to positive effects in future research.
BRAIN AND BEHAVIOR
(2021)
Article
Neurosciences
Justine Cinq-Mars, Anna Blumenthal, Alessa Grund, Sebastien Hetu, Isabelle Blanchette
Summary: Individuals are faster at detecting threatening stimuli than neutral stimuli, and this threat superiority effect is modulated by the dorsolateral prefrontal cortex (DLPFC). This study found that even at the earliest stage, the neural signature of rapid attentional detection of threat is influenced by the right DLPFC.
Article
Biochemistry & Molecular Biology
Laetitia Imbert, Remi Moirand, Benoit Bediou, Olivier Koenig, Gabrielle Chesnoy, Eric Fakra, Jerome Brunelin
Summary: Research suggests that applying transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) may improve emotional processing accuracy in patients with major depressive disorder (MDD). This finding provides a new possibility for alleviating depressive symptoms.
Article
Pharmacology & Pharmacy
Xingxing Li, Meng Chen, Qinqin Liu, Chao Zheng, Chang Yu, Guangwei Hou, Zan Chen, Yiqing Chen, Yinping Chen, Guidong Zhu, Dongsheng Zhou, Weiqian Xu
Summary: This study used TMS-EEG techniques to study the cortical activity of patients with major depressive disorder (MDD) and its correlation with clinical symptoms, providing an electrophysiological basis for clinical diagnosis.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Psychology, Experimental
Kristof Hoorelbeke, Nathan Van den Bergh, Rudi De Raedt, Marieke Wichers, Casper J. Albers, Ernst H. W. Koster
Summary: Studies suggest that cognitive control training has potential as a preventive intervention for depression, but little is known about its underlying mechanisms. This study used an experimental manipulation of cognitive control to investigate its direct effects on affect, emotion regulation, residual symptomatology, and resilience in remitted depressed patients. The findings showed that cognitive control training had beneficial effects on rumination and played a causal role in emotion regulation. However, it did not have immediate effects on residual symptoms or resilience, and did not impact the complex interplay between these variables. Overall, the immediate effects of cognitive control training on daily functioning were limited.
Article
Psychology, Multidisciplinary
Matias M. Pulopulos, Kristof Hoorelbeke, Sophie Vandenbroucke, Kim Van Durme, Jill M. Hooley, Rudi De Raedt
Summary: Research shows that self-esteem, expectancy, and cognitive control are related and play a role in stress regulation. High self-esteem is associated with higher self-efficacy, which is related to better attentional and anxiety control and lower perceived stress. Higher perceived stress is linked to more distress symptoms through increased rumination. This study provides a data-driven examination of how individuals with low self-esteem, expectancy, and deficits in cognitive control may struggle with daily stressors.
CURRENT PSYCHOLOGY
(2023)
Article
Psychology, Biological
Stefanie De Smet, Cristina Ottaviani, Bart Verkuil, Mitchel Kappen, Chris Baeken, Marie-Anne Vanderhasselt
Summary: Perseverative cognitions can induce stress and affect mental health. This study found that transcutaneous auricular vagus nerve stimulation (taVNS) significantly reduced cognitive rigidity after psychosocial stress. While there were no direct effects on autonomic correlates of perseverative cognition, individual differences in perseverative thinking significantly influenced the effects of taVNS on heart rate variability (HRV). The findings emphasize the connection between perseverative cognitions and vagus nerve functioning.
Article
Psychology, Biological
O. Martin-Garcia, R. De Raedt, M. Godara, C. Ottaviani, A. Sanchez-Lopez
Summary: Flexible attention towards relevant emotional information depending on specific motivational self-focuses underlies resilience. In this study, it was found that individuals with high promotion or prevention levels had difficulties in switching affective attention depending on the motivational context. Results support the idea that context-based affective attention flexibility depends on specific motivational self-focuses.
LEARNING AND MOTIVATION
(2023)
Review
Food Science & Technology
Marcus Schmidt, Marianna Raczyk
Summary: FODMAPs are a type of carbohydrates that can trigger symptoms and discomfort in patients with gastrointestinal disorders. Researchers have explored various approaches, such as using yeast, lactic acid bacteria, germination or enzymes, to produce low-FODMAP baking products. The selection of appropriate ingredients and the maintenance of sensory and nutritional quality are also important considerations.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Multidisciplinary Sciences
Malvika Godara, Jonas Everaert, Alvaro Sanchez-Lopez, Jutta Joormann, Rudi De Raedt
Summary: The COVID-19 pandemic has had a significant impact on global mental health. Risk factors such as intolerance of uncertainty and maladaptive emotion regulation are associated with increased psychopathology, while protective factors such as cognitive control and cognitive flexibility have been shown to protect mental health during the pandemic. However, the specific pathways through which these factors affect mental health during the pandemic are still unclear.
SCIENTIFIC REPORTS
(2023)
Article
Family Studies
Joke Heylen, Samuel Budniok, Magali van de Walle, Rudi De Raedt, Patricia Bijttebier, Simon De Winter, Guy Bosmans
Summary: Latent growth curve modeling was used to investigate the link between attachment, effortful control (EC), and maladaptive development during middle childhood. The results showed that secure attachment was associated with higher EC, but EC development was only linked with baseline self-reported trust. Moreover, self-reported trust was indirectly linked with change in externalizing problems over time through EC development.
JOURNAL OF EARLY ADOLESCENCE
(2023)
Article
Behavioral Sciences
Michele Schmitter, Marie-Anne Vanderhasselt, Jan Spijker, Jasper A. J. Smits, Janna N. Vrijsen
Summary: Despite the well-known benefits of exercise in reducing depressive symptoms, the psychological mechanisms underlying this effect are still unclear. This experimental study examined the immediate impact of exercise on mood, depressotypic memory bias, and state rumination, with trait rumination tested as a possible moderator. Non-regular exercisers (N = 100) were randomly assigned to either exercise or rest, and their affect and memory bias were assessed after the intervention. The results showed that exercise led to increased positive affect, but did not significantly affect memory bias or depression-related mood and rumination.
COGNITIVE BEHAVIOUR THERAPY
(2023)
Article
Psychology, Experimental
Ivan Blanco, Teresa Boemo, Oscar Martin-Garcia, Ernst H. W. Koster, Rudi De Raedt, Alvaro Sanchez-Lopez
Summary: The aim of this research was to develop and test the efficacy of an online contingent attention training to improve emotion regulation and reduce emotional symptom levels in major stressors. Two proof-of-principle studies were conducted with undergraduates and individuals from the general population. The OCAT group showed significant improvements in attention and interpretation biases and experienced reductions in rumination and anxiety symptoms.
COGNITIVE RESEARCH-PRINCIPLES AND IMPLICATIONS
(2023)
Article
Psychology, Biological
Zefeng Li, Matias Pulopulos, Jens Allaert, Stefanie De Smet, Linde De Wandel, Mitchel Kappen, Louise Puttevils, Lais B. Razza, Emmanuelle Schoonjans, Gert Vanhollebeke, Chris Baeken, Rudi De Raedt, Marie-Anne Vanderhasselt
Summary: The results of this study in a large sample of healthy individuals indicate that vagally-mediated heart rate variability (vmHRV) is not a marker of trait rumination (as measured by the Ruminative Response Scale).
Article
Psychology, Developmental
Sam L. B. Bonduelle, Rudi De Raedt, Caroline Braet, Edward Campforts, Chris Baeken
Summary: Feeling and/or being criticized is a known risk factor for various psychiatric disorders in adolescents, but the relationship between social stressors and the development of psychopathological symptoms is not fully understood. Identifying vulnerable adolescent subgroups to parental criticism is clinically relevant.
JOURNAL OF EXPERIMENTAL CHILD PSYCHOLOGY
(2023)
Article
Psychology, Clinical
Marie-Anne Vanderhasselt, Alvaro Sanchez-Lopez, Matias Pulopulos, Lais B. Razza, Stefanie De Smet, Andre Russowsky Brunoni, Chris Baeken, Rudi De Raedt, Jens Allaert
Summary: The prefrontal cortex is crucial for cognitive processes and can be modulated by transcranial direct current stimulation (tDCS). However, there is limited research on the effects of tDCS on emotional material processing in the prefrontal cortex, particularly in proactive and reactive modes of cognitive control. This study found that active right-sided tDCS reduced performance and resource allocation in both proactive and reactive modes of cognitive control. These findings emphasize the importance of further research on the effects of tDCS on cognitive engagement, especially in clinical trials using this electrode montage.
INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY
(2023)
Article
Psychology, Multidisciplinary
Kristof Hoorelbeke, Lien Faelens, Rudi De Raedt, Ernst H. W. Koster
Summary: The use of social networking sites (SNS) has diverse impacts on functioning, and these impacts can be influenced by contextual factors. This cross-sectional study examined the connections between SNS use, functioning indicators, and COVID-19 relevant factors. The findings revealed that the associations between SNS use, depressive symptomatology, and loneliness differed depending on COVID-19 status and housing condition. This study highlights the complex moderation of SNS use patterns on (dys)functioning by contextual factors.
COMPUTERS IN HUMAN BEHAVIOR REPORTS
(2023)
Review
Behavioral Sciences
Gert Vanhollebeke, Fiebe Aers, Lauren Goethals, Rudi De Raedt, Chris Baeken, Pieter van Mierlo, Marie-Anne Vanderhasselt
Summary: This study systematically reviewed the Cyberball-ERP literature and evaluated the effects of social exclusion and paradigm characteristics on ERP changes, finding that expectancy violations better explain the results of the P3 complex.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)