期刊
PSYCHO-ONCOLOGY
卷 22, 期 6, 页码 1396-1401出版社
WILEY
DOI: 10.1002/pon.3155
关键词
lung cancer; uncertainty; psychological adjustment; oncology; quality of life
资金
- [1K23CA149079-01A1]
Background For many patients with lung cancer, disease progression occurs without notice or with vague symptoms, and unfortunately, most treatments are not curative. Given this unpredictability, we hypothesized the following: (1) poorer psychological adjustment (specifically, more depressive symptoms, higher perceptions of stress, and poorer emotional well-being) would be associated with higher intolerance for uncertainty, higher perceived illness-related ambiguity, and their interaction; and (2) greater avoidance would mediate associations between higher intolerance of uncertainty and poorer psychological adjustment. Methods Participants (N=49) diagnosed with lung cancer at least 6months prior to enrollment completed the Center for Epidemiologic Studies - Depression Scale, the Functional Assessment of Cancer Therapy - Lung Emotional Well-being subscale, the Perceived Stress scale, the Intolerance of Uncertainty scale, the Mishel Uncertainty in Illness Scale Ambiguity subscale, the Impact of Event - Revised Avoidance subscale, and the Short-scale Eysenck Personality Questionnaire - Revised Neuroticism subscale. Mean age was 64.2years (standard deviation [SD]=11.0), mean years of education was 15.6 (SD=3.1), and 71.4% were female. Hypotheses were tested with regression analyses, adjusted for neuroticism. Results Higher perceptions of stress and poorer emotional well-being were associated with higher levels of intolerance of uncertainty and higher perceived illness-related ambiguity. Non-somatic depressive symptoms were associated with higher levels of intolerance of uncertainty. Avoidance was found to mediate relations of intolerance of uncertainty with non-somatic depressive symptoms and emotional well-being only. Conclusions Findings suggest that interventions to address avoidance and intolerance of uncertainty in individuals with lung cancer may help improve psychological adjustment. Copyright (c) 2012 John Wiley & Sons, Ltd.
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