期刊
PSYCHO-ONCOLOGY
卷 19, 期 12, 页码 1340-1347出版社
JOHN WILEY & SONS LTD
DOI: 10.1002/pon.1764
关键词
randomized controlled trial; existential; psychosocial; intervention; advanced ovarian cancer; oncology
资金
- Canadian Institutes of Health Research (CIHR)-Canadian Cancer Society (CCS)/Strategic Research Training Program in Palliative Care
- Canadian Cancer Society (CCS) [18745]
- Canadian Cancer Society Research Institute (CCSRI) Sociobehavioural Cancer Research Network
Objective: This pilot study aimed to provide supportive evidence for the acceptability and usefulness of the Meaning-Making intervention (MMi) in patients newly diagnosed with Stage III or IV ovarian cancer, and to provide estimates of parameters needed to design a full-scale study. Methods: A randomized controlled trial with 24 patients (12 experimental and 12 control) was conducted. Existential well-being (primary outcome), overall quality of life, distress, anxiety, depression and self-efficacy were measured. Results: Compared to the control group, patients in the experimental group had a better sense of meaning in life at one and three months post-intervention. Conclusion: The MMi seems a promising intervention for advanced cancer patients, and a full randomized controlled trial is warranted to further investigate its efficacy. Copyright (C) 2010 John Wiley & Sons, Ltd.
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