Article
Medicine, General & Internal
Se Hyun Oh, Ju Hyeon Kim, Seung Tae Seong, Jun Young Park, Jae Hyun Lee, Ghi Chan Kim, Ho Joong Jeong, Young Joo Sim
Summary: This study investigated the impact of axillary site radiation therapy on lymphoscintigraphy in breast cancer-related lymphedema patients who underwent sentinel lymph node dissection. The results suggest that both SLND and aRTx affect the activity of axillary lymph nodes and adversely affect lymphatic flow, becoming risk factors for lymphedema. Additionally, lymphedema may develop even in patients with normal lymphoscintigraphy.
Review
Surgery
Nur Amalina Che Bakri, Richard M. Kwasnicki, Naairah Khan, Omar Ghandour, Alice Lee, Yasmin Grant, Aleksander Dawidziuk, Ara Darzi, Hutan Ashrafian, Daniel R. Leff
Summary: This study evaluated the impact of axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SLNB) on upper limb morbidity in breast cancer patients. The results showed that ALND patients had higher prevalence of lymphedema, pain, reduced strength, and range of motion compared with SLNB patients. These findings support the continued de-escalation of axillary surgery.
Article
Oncology
Massimiliano Gennaro, Chiara Listorti, Luigi Mariani, Marco Maccauro, Giulia Bianchi, Giuseppe Capri, Ilaria Maugeri, Laura Lozza, Maria Carmen De Santis, Secondo Folli
Summary: In this study, we followed up on 100 consecutive axillary node-positive patients treated with ARM-SAD and found a low rate of axillary failure, indicating that the ARM-SAD procedure is oncologically safe.
Article
Medicine, General & Internal
Hee Jun Choi, Jai Min Ryu, Byung Joo Chae, Seok Jin Nam, Jonghan Yu, Se Kyung Lee, Jeong Eon Lee, Seok Won Kim
Summary: This study evaluated pathologic lymph node metastasis in breast cancer with cytology-proven axillary metastasis and found that even in patients without sentinel lymph node metastasis, a significant proportion had lymph node metastasis. Sentinel lymph node biopsy without axillary lymph node dissection may not be safe for patients with cytology-proven axillary metastasis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Qianqian Yuan, Jinxuan Hou, Yukun He, Yiqian Liao, Lewei Zheng, Gaosong Wu
Summary: ALND based on BLL can minimize surgical extent for node-positive breast cancer patients, potentially reducing the occurrence of BCRL.
Article
Oncology
Eline E. F. Verreck, Julia E. C. van Steenhoven, Anne Kuijer, Marissa C. van Maaren, Janine M. Simons, Sabine Siesling, Thijs van Dalen
Summary: A study found that the frequency of ALND in SLN+ breast cancer patients undergoing mastectomy significantly decreased over time, while the frequency of PMRT increased. Factors such as age, tumor subtype, N stage, and hospital type affected the likelihood of patients undergoing ALND.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Toralf Reimer
Summary: The local treatment of axilla in early breast cancer patients without clinically evident lymph node metastases is a subject of debate. Various prospective randomized surgical trials are currently being conducted to evaluate the safety of omitting sentinel lymph node biopsy in upfront breast-conserving surgery and neoadjuvant setting. These trials aim to determine whether it is possible to make therapeutic decisions without pathologic evaluation of nodal status. Additionally, ongoing trials are investigating the possibility of de-escalating surgery based on the response to neoadjuvant systemic therapy.
Article
Oncology
Ya Qiu, Xiang Zhang, Zhiyuan Wu, Shiji Wu, Zehong Yang, Dongye Wang, Hongbo Le, Jiaji Mao, Guochao Dai, Xuwei Tian, Renbing Zhou, Jiayi Huang, Lanxin Hu, Jun Shen
Summary: The MRI-clinical-radiomics nomograms developed in this study showed high predictive performance in determining axillary NSLN status in SLN-positive breast cancer patients, reducing overtreatment and optimizing personalized surgical strategies.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Sacha A. Roberts, Tessa C. Gillespie, Amy M. Shui, Cheryl L. Brunelle, Kayla M. Daniell, Joseph J. Locascio, George E. Naoum, Alphonse G. Taghian
Summary: This study aimed to determine the relationship between postoperative weight change and breast cancer-related lymphedema. The findings suggest that weight loss alone may not decrease the risk of developing BCRL.
Article
Oncology
Sophie H. H. Chung, Susanna W. L. de Geus, Grant Shewmaker, Kelsey S. S. Romatoski, Frederick T. T. Drake, Naomi Y. Y. Ko, Andrea L. L. Merrill, Ariel E. E. Hirsch, Jennifer F. F. Tseng, Teviah E. E. Sachs, Michael R. R. Cassidy
Summary: This study compared the survival outcomes of men with positive sentinel lymph nodes after either sentinel lymph node biopsy (SLNB) alone or complete axillary dissection (ALND) in breast cancer. The results showed that ALND was associated with superior survival compared to SLNB alone in early-stage male breast cancer patients.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Peiyong Li, Ciqiu Yang, Junsheng Zhang, Yitian Chen, Xiaoqi Zhang, Minting Liang, Na Huang, Yilin Chen, Kun Wang
Summary: Sentinel lymph node biopsy can provide survival results equivalent to axillary lymph node dissection for patients with cN0 and T1-2 breast cancer; however, whether it can be performed on patients with T3-4c breast cancer is still controversial.
Article
Oncology
Khairunnisa' Md Yusof, Sherina Mohd Sidik, Rozi Mahmud, Maha Abdullah, Kelly A. Avery-Kiejda, Rozita Rosli
Summary: This study aimed to assess psychological distress status in Malaysian breast cancer survivors and factors that affected the condition. The study found that arm morbidities after breast surgery were associated with higher levels of depression and anxiety. In addition, receiving fewer post-rehabilitation treatments and having a family history of cancer were correlated with higher anxiety levels.
Article
Oncology
Allan Jazrawi, Eirini Pantiora, Shahin Abdsaleh, Daniel Vasiliu Bacovia, Staffan Eriksson, Henrik Leonhardt, Fredrik Warnberg, Andreas Karakatsanis
Summary: The combination of SPIO MRI-LG and MagUS for SLN detection offers a minimally invasive approach for axillary evaluation, reducing the need for diagnostic surgery.
Article
Oncology
James Sun, Brittany J. Mathias, Christine Laronga, Weihong Sun, Jun-Min Zhou, William J. Fulp, John Kiluk, M. Catherine Lee
Summary: The study found that completion axillary lymph node dissection (CLND) after mastectomy did not significantly reduce recurrence or improve overall survival (OS) in clinically node-negative, sentinel lymph node (SLN)-positive breast cancer patients. However, completion of postmastectomy radiotherapy was associated with improved OS.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK
(2021)
Article
Medicine, General & Internal
Shinichi Terada, Tomohito Tanaka, Hikaru Murakami, Hiromitsu Tsuchihashi, Akihiko Toji, Atsushi Daimon, Shunsuke Miyamoto, Ruri Nishie, Shoko Ueda, Sousuke Hashida, Natsuko Morita, Hiroshi Maruoka, Hiromi Konishi, Yuhei Kogata, Kohei Taniguchi, Kazumasa Komura, Masahide Ohmichi
Summary: This study evaluated and compared the occurrence rate of lymphatic complications between sentinel node biopsy (SNB) and pelvic lymphadenectomy (LND) for endometrial cancer (EC). The results showed that SNB had a significantly lower occurrence rate of lower-extremity lymphedema (LEL) and pelvic lymphocele (PL) compared to pelvic LND.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Susan Williamson, Thomas F. Hack, Munirah Bangee, Valerio Benedetto, Kinta Beaver
Summary: The study found that participants were concerned that assessments were becoming bureaucratic tick-box exercises which did not meet patients' needs. Barriers to completion included time, staff shortages, lack of confidence, privacy, and resources. Facilitators included privacy for confidential discussions, training, confidence in knowledge and skills, and referral to resources.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Education & Educational Research
Shane Sinclair, Thomas F. Hack, Susan McClement, Shelley Raffin-Bouchal, Harvey Max Chochinov, Neil A. Hagen
BMC MEDICAL EDUCATION
(2020)
Article
Oncology
Thomas F. Hack, J. Dean Ruether, Marshall Pitz, Brian Thiessen, Lesley F. Degner, Dan Chateau
Summary: The study found that brain tumor patients who received primary treatment consultation recordings reported better perception of being informed at 1 week post-consultation compared to those who did not, but this difference was no longer significant at 3 and 6 months. There were no significant differences between the two groups in terms of satisfaction with cancer care, satisfaction with the doctor, and depression or anxiety, potentially due to under-powering of the study.
SUPPORTIVE CARE IN CANCER
(2021)
Review
Education, Scientific Disciplines
Shane Sinclair, Jane Kondejewski, Priya Jaggi, Liz Dennett, Amanda L. Roze des Ordons, Thomas F. Hack
Summary: The study found that most compassion education interventions are limited in their focus on a single domain of compassion, lack of comparator/control group, and do not evaluate retention, sustainability, and translation to clinical practice over time. The authors suggest that future compassion education interventions should use multimodal teaching methods and incorporate patient, preceptor, and peer evaluations.
Review
Education & Educational Research
Shane Sinclair, Jane Kondejewski, Priya Jaggi, Amanda L. Roze des Ordons, Aliya Kassam, K. Alix Hayden, Daranne Harris, Thomas F. Hack
Summary: This review study used realist review methodology to examine compassion training for practicing healthcare providers, identifying the attributes that explain the success or failure of such training. The study found that different contexts and mechanisms can impact the outcomes of compassion training on healthcare providers' attitudes, knowledge, skills, behaviors, and clinical processes.
BMC MEDICAL EDUCATION
(2021)
Article
Medicine, General & Internal
Shane Sinclair, Thomas F. Hack, Cara C. MacInnis, Priya Jaggi, Harrison Boss, Susan McClement, Aynharan Sinnarajah, Genevieve Thompson
Summary: This study developed and validated a clinically informed, psychometrically rigorous, patient-reported compassion measure. The results showed that the measure had good reliability and validity, and was positively correlated with other assessment tools, indicating that patients who experienced more compassion reported higher well-being.
Article
Public, Environmental & Occupational Health
Kendra L. Rieger, Marlyn Bennett, Donna Martin, Thomas F. Hack, Lillian Cook, Bobbie Hornan
Summary: Engaging with First Nations women to explore the use of digital storytelling as a research method revealed deep insights into their experiences and provided guidance for future qualitative studies. Incorporating Indigenous knowledge into healthcare services is important in addressing health inequities. Digital storytelling can create a culturally safe space for authentic patient engagement and enhance the understanding of complex health issues.
QUALITATIVE HEALTH RESEARCH
(2021)
Article
Education, Scientific Disciplines
Shane Sinclair, Daranne Harris, Jane Kondejewski, Amanda L. Roze des Ordons, Priya Jaggi, Thomas F. Hack
Summary: Compassion training programs should be rooted in patient needs and experiences, with patient-reported compassion scores integrated before and after training. The programs should be led by highly qualified educators with a dedicated contemplative practice and leadership support to create an ethos of compassion throughout the organization.
TEACHING AND LEARNING IN MEDICINE
(2022)
Article
Pharmacology & Pharmacy
Kevin J. Friesen, Jamie Falk, Dan Chateau, I. Fan Kuo, Shawn Bugden
Summary: The association between PPI use and dementia is still uncertain. This study used a population-based and a high-dimension propensity-score matched cohort to re-examine this issue. The results showed that high-dose PPI users had a higher risk of dementia, but this association disappeared after adjusting for medical diagnoses and drug use.
CLINICAL PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Oncology
Kendra L. Rieger, Thomas F. Hack, Miriam A. Duff, Heather J. Campbell-Enns, Christina H. West
Summary: The purpose of this study was to explore the experiences of cancer patients participating in a mindfulness-based expressive arts group intervention and to identify individual and contextual factors influencing their experiences. Findings revealed that mindfulness facilitated participants in letting go of rumination and calming their minds, allowing them to fully engage in arts activities. The combination of mindfulness and the arts created a unique healing space where individual work was nested within group processes.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Medicine, Research & Experimental
Amelia Hyatt, Ruby Lipson-Smith, Karla Gough, Phyllis Butow, Michael Jefford, Thomas F. Hack, Sandra Hale, Emiliano Zucchi, Shane White, Uldis Ozolins, Penelope Schofield
Summary: The study aimed to assess the feasibility of designing research inclusive of migrants who do not speak English. The results indicated that methods utilized in the study supported the inclusion of migrant oncology patients in research, and a future multi-site RCT efficacy assessment is feasible.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2022)
Review
Health Care Sciences & Services
Shane Sinclair, Jane Kondejewski, Thomas F. Hack, Harrison C. D. Boss, Cara C. MacInnis
Summary: This study compared recently updated or newly published compassion measures and found that the Sinclair Compassion Questionnaire (SCQ) was the most comprehensive and methodologically rigorous measure for evaluating compassion in healthcare. It adhered to measure development guidelines, had higher scores than other measures, and provided empirical evidence for compassion evaluations.
PATIENT-PATIENT CENTERED OUTCOMES RESEARCH
(2022)
Meeting Abstract
Oncology
Phyllis Butow, Heather L. Shepherd, Joanne Shaw, Liesbeth Geerligs, Lindy Masya, Jessica Cuddy, Mona Faris, Haryana M. Dhillon, Thomas F. Hack, Afaf Girgis, Tim Luckett, Melanie Lovell, Brian Kelly, Philip Beale, Peter Grimison, Rosalie Viney, Nicole M. Rankin, Laura Kirsten, Josephine Clayton
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Genevieve N. Thompson, Susan E. McClement, Sheryl Peters, Thomas F. Hack, Harvey Chochinov, Laura Funk
Summary: This study aims to examine the experience of delivering and receiving intimate personal care in nursing homes, highlighting the importance of creating a relational space that promotes integrity for providing quality person-centered care. The provision of intimate personal care involves a complex interplay at the level of resident/care provider interaction, health care organization, and policy, with each level interacting with and influencing the others. The identified components in the model may serve as a basis for further examination of resident experiences of quality intimate personal care.
INTERNATIONAL JOURNAL OF QUALITATIVE STUDIES ON HEALTH AND WELL-BEING
(2021)
Article
Gerontology
Genevieve Thompson, Thomas Hack, Kerstin Rodger, Phil St John, Harvey Chochinov, Susan McClement
Summary: Research has identified the unique information and support needs of family caregivers of nursing home residents with dementia, ranging from disease-specific to general issues related to life in a nursing home. Health care providers should proactively provide information on dementia and end-of-life care, as family caregivers may not always recognize their need for such information.
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2021)