Article
Neurosciences
Gabriele Russo, Xavier Helluy, Mehdi Behroozi, Denise Manahan-Vaughan
Summary: The study proposes a habituation strategy for awake rats undergoing fMRI, which enables stable image acquisition with low motion artifacts by gradually training the rats over a period of three weeks. Effective habituation results in low stress levels and minimal head motion artifacts during fMRI, allowing for precise brain mapping of BOLD signals and supporting the discrimination of cognitive processes without stress confounds.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Neurosciences
Ivanny Carolina Marchant, Steren Chabert, Jonathan Martinez-Pinto, Ramon Sotomayor-Zarate, Ricardo Ramirez-Barrantes, Lilian Acevedo, Claudio Cordova, Pablo Olivero
Summary: Menopause transition is characterized by vulnerability due to estrogen deficiency, which can have detrimental effects on the body such as chronic inflammation and increased risk of age-related disorders. Despite the beneficial effects of estrogen on neurological tissues, clinical evidence regarding hormone treatment in menopausal women is inconclusive. Studies have shown that improved verbal memory is a significant finding from research, highlighting the potential neuroprotective effects of estrogen.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Neurosciences
Rong Li, Jun Hwan Ryu, Peter Vincent, Max Springer, Dan Kluger, Erik A. Levinsohn, Yu Chen, Huafu Chen, Hal Blumenfeld
Summary: The study identified a shared network of transient fMRI increases in subcortical arousal and cortical salience/attention networks, which were consistent across different tasks and study populations. Furthermore, it found that sustained activity in these networks was more variable, and the function of the transient pulse in these networks remains unknown.
Article
Biology
Andrea Ciorba, Stavros Hatzopoulos, Cristina Cogliandolo, Chiara Bianchini, Martina Renna, Luca Perrucci, Magdalena Skarzynska, Piotr Henryk Skarzynski, Paolo Campioni, Corrado Cittanti, Aldo Carnevale, Melchiore Giganti, Stefano Pelucchi
Summary: The study utilized fMRI to evaluate brain maps generated from healthy individuals' response to olfactory stimuli, revealing that the left anterior insula is primarily activated by odorous stimuli and other cortical areas are also involved.
Article
Neurosciences
Huimin Wu, Yu Song, Xinyi Yang, Shanshan Chen, Honglin Ge, Zheng Yan, Wenzhang Qi, Qianqian Yuan, Xuhong Liang, Xingjian Lin, Jiu Chen
Summary: This study investigated the multimodal alterations of the dorsal attention network (DAN) in subjects with subjective cognitive decline (SCD) and amnestic mild cognitive impairment (aMCI), and found that these alterations were closely related to cognitive performance. The combined multiple indicators of DAN could serve as potential neuroimaging markers for the diagnosis of preclinical and early-stage Alzheimer's disease (AD).
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Review
Neurosciences
Pinar Demirayak, Gopikrishna Deshpande, Kristina Visscher
Summary: The emergence of ultra-high field MRI scanners has enabled researchers to study the human brain in detail. This non-invasive technique allows for the observation of differences between cortical layers, and layer-specific fMRI can distinguish feedback and feedforward pathways, thus contributing to the understanding of brain function.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Xin Zhang, Jiayue Liu, Yang Yang, Shijie Zhao, Lei Guo, Junwei Han, Xintao Hu
Summary: The study examined the test-retest reliability of dynamic functional connectivity (dFC) in functional magnetic resonance imaging (fMRI) under natural viewing condition, revealing significantly improved reliability compared to resting state. This suggests that naturalistic paradigms may enhance the study of functional brain networks using fMRI.
HUMAN BRAIN MAPPING
(2022)
Review
Behavioral Sciences
Sophia Linguiti, Jacob W. Vogel, Valerie J. Sydnor, Adam Pines, Nick Wellman, Allan Basbaum, Claudia R. Eickhoff, Simon B. Eickhoff, Robert R. Edwards, Bart Larsen, Andrew McKinstry-Wu, J. Cobb Scott, David R. Roalf, Vaishnavi Sharma, Eric C. Strain, Gregory Corder, Robert H. Dworkin, Theodore D. Satterthwaite
Summary: Functional magnetic resonance imaging (fMRI) is increasingly used to study the acute impact of psychedelics on the human brain. A systematic review of fMRI studies revealed substantial heterogeneity in design and methodology. However, the review identified consistent findings: psilocybin and LSD modulate connectivity in the sensorimotor-association cortical axis, while ketamine increases activation in the dorsomedial prefrontal cortex.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Review
Endocrinology & Metabolism
Ziqi Zhang, Yu Chen, Xiqiao Zhou, Su Liu, Jiangyi Yu
Summary: This study searched the literature on functional magnetic resonance imaging (fMRI) for the assessment of renal alterations in diabetic kidney disease. 24 publications were included in the study, with a total of 1550 subjects. The study found that renal blood flow (RBF) values were significantly lower in the DKD group compared to the HV group on ASL-MRI. The FA values were also significantly lower in the DKD group on DTI-MRI. There were no significant differences in the other parameters on BOLD-MRI or IVIM-DWI.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Neurosciences
Yimeng Zeng, Fuxiang Tao, Zaixu Cui, Liyun Wu, Jiahua Xu, Wenshan Dong, Chao Liu, Zhi Yang, Shaozheng Qin
Summary: The study identified two distinct dynamic states of intrinsic connectivity patterns based on BLA and CMA using fMRI and K-means clustering in two groups of young healthy individuals. Higher skin conductance level was found in the integration state compared to the segregation state in another dataset. Additionally, machine learning analysis revealed that the time-varying BLA and CMA intrinsic connectivity patterns had higher predictive values for fluctuations in skin conductance level in the integration state.
Review
Neurosciences
Xiaoyi Li, Kai Zhang, Xiao He, Jinyun Zhou, Chentao Jin, Lesang Shen, Yuanxue Gao, Mei Tian, Hong Zhang
Summary: Recent neuroimaging studies have provided insights into the neurobiological processes associated with ASD, with MRI revealing abnormal developmental trajectories, functional MRI highlighting disrupted neural networks, and PET/SPECT imaging indicating metabolic and neurotransmitter abnormalities contributing to aberrant neural circuits in ASD.
NEUROSCIENCE BULLETIN
(2021)
Article
Neurosciences
Zhoufan Jiang, Yanming Wang, ChenWei Shi, Yueyang Wu, Rongjie Hu, Shishuo Chen, Sheng Hu, Xiaoxiao Wang, Bensheng Qiu
Summary: By incorporating attention modules and four-dimensional convolution operations, the proposed model accurately interprets brain cognitive states from neuroimaging signals and outperforms previous research in task benchmarks, showing promising potential for neuroscience research.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Thomas Liebe, Milos Dordevic, Jorn Kaufmann, Araks Avetisyan, Martin Skalej, Notger Mueller
Summary: This study investigates the relationship between the brainstem nucleus locus coeruleus (LC) and functional disturbances in mild cognitive impairment (MCI) patients. It found that functional connectivity (fc) between LC and anterior cingulate cortex and left anterior insula was elevated in MCI patients, while the fc between LC and right temporoparietal junction and posterior cingulate cortex was decreased. Additionally, the study found a positive correlation between LC to right temporoparietal junction connectivity and MMSE scores in MCI patients, as well as hyperactivation of the left-insula salience network.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Kangjoo Lee, Corey Horien, David O'Connor, Bronwen Garand-Sheridan, Fuyuze Tokoglu, Dustin Scheinost, Evelyn M. R. Lake, R. Todd Constable
Summary: This study investigates the impact of arousal levels indexed by pupil area on the integration of large-scale brain networks using simultaneous resting state functional magnetic resonance imaging (fMRI) and pupillometry. The results show a decrease in between-network integration and inter-subject variability at low arousal compared to high arousal, with differences occurring across regions of multiple brain networks. State-dependent changes in network integration within hub regions suggest a brain state transition characterized by global synchronization and reduced network overlaps. Arousal modulation has a brain-wide impact on high-level between-network communications. Additionally, changes in fMRI signal correlation structures and the choice of global signal regression can influence conclusions when studying arousal modulations.
Editorial Material
Biology
Polytimi Frangou, William T. Clarke
Summary: By combining methods that monitor blood oxygenation and biochemicals, researchers have discovered how the brain processes both perceived and unperceived stimuli.
Article
Neurosciences
Erin Walsh, Hannah Carl, Tory Eisenlohr-Moul, Jared Minkel, Andrew Crowther, Tyler Moore, Devin Gibbs, Chris Petty, Josh Bizzel, Moria J. Smoski, Gabriel S. Dichter
NEUROPSYCHOPHARMACOLOGY
(2017)
Article
Clinical Neurology
R. K. Greene, M. Spanos, C. Alderman, E. Walsh, J. Bizzell, M. G. Mosner, J. L. Kinard, G. D. Stuber, T. Chandrasekhar, L. C. Politte, L. Sikich, G. S. Dichter
JOURNAL OF NEURODEVELOPMENTAL DISORDERS
(2018)
Editorial Material
Psychiatry
Gabriel S. Dichter
Article
Clinical Neurology
Erin C. Walsh, Tory A. Eisenlohr-Moul, Jared Minkel, Joshua Bizzell, Chris Petty, Andrew Crowther, Hannah Carl, Moria J. Smoski, Gabriel S. Dichter
JOURNAL OF AFFECTIVE DISORDERS
(2019)
Article
Behavioral Sciences
Rachel K. Greene, Shuting Zheng, Jessica L. Kinard, Maya G. Mosner, Christopher A. Wiesen, Daniel P. Kennedy, Gabriel S. Dichter
Review
Psychology, Biological
Rachel K. Greene, Erin Walsh, Maya G. Mosner, Gabriel S. Dichter
BIOLOGICAL PSYCHOLOGY
(2019)
Article
Substance Abuse
Jennifer Y. Yi, Gabriel S. Dichter, Elizabeth D. Reese, Ryan P. Bell, Anna D. Bartuska, Jennifer R. Stein, Stacey B. Daughters
DRUG AND ALCOHOL DEPENDENCE
(2019)
Meeting Abstract
Neurosciences
Paul Cernasov, Rachel Greene, Jessica Kinard, Tate Halverson, Sarah Lowery, Marcy McLamb, David Choi, Maria Cruz, Kristen Armel, Shauntell Luke, Macey Arnold, Angela Pisoni, Lisalynn Kelley, Gabriela Nagy, Erin Walsh, Moria Smoski, Gabriel Dichter
BIOLOGICAL PSYCHIATRY
(2019)
Meeting Abstract
Neurosciences
Crystal Schiller, Gabriel Dichter, Joshua Bizzell, Sarah Johnson, Erin Richardson, Peter Schmidt, Aysenil Belger, David Rubinow
BIOLOGICAL PSYCHIATRY
(2019)
Article
Neurosciences
Shanna L. Resendez, Vijay Mohan K. Namboodiri, James M. Otis, Louisa E. H. Eckman, Jose Rodriguez-Romaguera, Randall L. Ung, Marcus L. Basiri, Oksana Kosyk, Mark A. Rossi, Gabriel S. Dichter, Garret D. Stuber
JOURNAL OF NEUROSCIENCE
(2020)
Article
Neurosciences
R. McKell Carter, Heejung Jung, Judy Reaven, Audrey Blakeley-Smith, Gabriel S. Dichter
FRONTIERS IN HUMAN NEUROSCIENCE
(2020)
Article
Medicine, Research & Experimental
Melissa J. M. Walsh, Kathryn Gibson, Megan Hynd, Tory A. Eisenlohr-Moul, Erin C. Walsh, Lauren Schiff, Fred Jarskog, David Lalush, Gabriel S. Dichter, Crystal E. Schiller
Summary: This clinical trial aims to investigate the neural and molecular mechanisms by which estradiol treatment improves symptoms of anhedonia and psychosis during the perimenopausal transition. The study will recruit 100 unmedicated women in the late-stage perimenopausal transition and assess clinical symptoms and neurobiological markers before and after estradiol treatment. This research will provide valuable insights into predicting, treating, and developing biomarkers for perimenopausal psychiatric symptoms.
Article
Psychology, Clinical
Gabriela A. Nagy, Paul Cernasov, Angela Pisoni, Erin Walsh, Gabriel S. Dichter, Moria J. Smoski
BEHAVIOR MODIFICATION
(2020)
Article
Psychology, Developmental
Maya G. Mosner, Jessica L. Kinard, Jasmine S. Shah, Sean McWeeny, Rachel K. Greene, Sarah C. Lowery, Carla A. Mazefsky, Gabriel S. Dichter
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2019)
Meeting Abstract
Neurosciences
Crystal Schiller, Aysenil Belger, Sarah Slightom, Erin Richardson, Joshua Bizzell, Peter Schmidt, Gabriel Dichter, David Rubinow
NEUROPSYCHOPHARMACOLOGY
(2017)