Article
Health Care Sciences & Services
Sunhae Kim, Hye-Kyung Lee, Kounseok Lee
Summary: Using machine learning analysis, participants' mood symptoms can be classified and predicted more accurately. The prediction results for depressive symptoms and hypomanic symptoms vary across different methods used.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Review
Clinical Neurology
Silvana Zito, Guido Nosari, Alessandro Pigoni, Chiara Moltrasio, Giuseppe Delvecchio
Summary: This review examines the relationship between testosterone levels and mood disorders, specifically major depressive disorder and bipolar disorder. The results from the reviewed studies were conflicting, with some showing low levels of testosterone in both disorders, while others showed a mixed picture of reduced, increased or no difference in testosterone levels. Overall, testosterone may serve as a useful biomarker in mood disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Gail I. S. Harmata, Ercole John Barsotti, Lucas G. Casten, Jess G. Fiedorowicz, Aislinn Williams, Joseph J. Shaffer, Jenny Gringer Richards, Leela Sathyaputri, Samantha L. Schmitz, Gary E. Christensen, Jeffrey D. Long, Marie E. Gaine, Jia Xu, Jake J. Michaelson, John A. Wemmie, Vincent A. Magnotta
Summary: This study found that the cerebellar cortex is smaller in individuals with bipolar disorder (BD). The study also suggests that external factors, such as sedatives and childhood experiences, may influence cerebellum structure in BD. Future research should consider these variables for consistent findings.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Psychiatry
Lauro Estivalete Marchionatti, Thyago Antonelli-Salgado, Isadora Nunes Erthal, Savio Luiz Santos Lopes, Luiza Silveira Lucas, Diego Barreto Reboucas, Ives Cavalcante Passos
Summary: This systematic review on the impact of disease progression in the treatment of bipolar disorder patients found that efficacy decreases with clinical progression, supporting early intervention. However, tailored recommendations cannot be made based on disease stages currently, highlighting the need for further research.
PSYCHIATRY RESEARCH
(2022)
Article
Psychiatry
Mai Uchida, Qasim Bukhari, Maura DiSalvo, Allison Green, Giulia Serra, Chloe Hutt Vater, Satrajit S. Ghosh, Stephen V. Faraone, John D. E. Gabrieli, Joseph Biederman
Summary: This study developed a quantitative predictive model for bipolar disorder using machine learning algorithms and clinical data. The predictors included behavioral problems, school functioning, and anxiety/depression and aggression scales. The results have important clinical and scientific implications for assessing the risk of bipolar disorder in children.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychiatry
Mario Simjanoski, Karen Jansen, Thaise Campos Mondin, Fernanda Pedrotti Moreira, Igor Soares Vieira, Ricardo Azevedo da Silva, Luciano Dias de Mattos Souza, Benicio N. Frey, Taiane de Azevedo Cardoso, Flavio Kapczinski
Summary: The study aimed to assess the differences in subjective cognitive dysfunction between major depressive disorder (MDD) and recently diagnosed Bipolar Disorder (BD) across euthymia and mood episodes. Results showed higher subjective cognitive dysfunction in individuals recently diagnosed with BD compared to those with MDD during euthymia.
PSYCHIATRY RESEARCH
(2021)
Article
Psychiatry
Mohan Ma, Chuman Xiao, Wenwen Ou, Guanyi Lv, Mei Huang, Xiaotian Zhao, Yaqi Qin, Yumeng Ju, Yan Zhang
Summary: This study examines the psychometric properties of the Affective Lability Scale-short form (ALS-SF) among Chinese patients with mood disorders. The results indicate that the ALS-SF has good reliability and validity for measuring affective lability in Chinese patients and can help clinicians distinguish between different mood disorders.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Psychology, Clinical
Sukanta Saha, Carmen C. W. Lim, Danielle L. Cannon, Lucinda Burton, Monique Bremner, Peter Cosgrove, Yan Huo, John J. McGrath
Summary: This study conducted a meta-analysis to explore the comorbidity between mood and anxiety disorders, finding consistent evidence of a substantial association regardless of diagnostic criteria, study timeframe, or adjustments. Clinicians should be aware of the high prevalence of this common comorbidity and ensure prompt identification and treatment.
DEPRESSION AND ANXIETY
(2021)
Article
Psychiatry
Roger S. McIntyre, Joshua D. Rosenblat, Nelson B. Rodrigues, Orly Lipsitz, David Chen-Li, Jung Goo Lee, Flora Nasri, Mehala Subramaniapillai, Kevin Kratiuk, Andrew Wang, Hartej Gill, Rodrigo B. Mansur, Roger Ho, Kangguang Lin, Yena Lee
Summary: The study found that intravenous ketamine can significantly improve cognitive function in TRD patients, especially in tests like DSST and PDQ-5-D. This improvement is mainly mediated by reduced depressive symptoms, indicating that ketamine has independent and rapid effects in promoting cognition.
PSYCHIATRY RESEARCH
(2021)
Review
Psychiatry
Katie Benitah, Ashley N. Siegel, Orly Lipsitz, Nelson B. Rodrigues, Shakila Meshkat, Yena Lee, Rodrigo B. Mansur, Flora Nasri, Leanna M. W. Lui, Roger S. McIntyre, Joshua D. Rosenblat
Summary: A systematic review of published clinical studies found no significant differences in the antidepressant response, tolerability, or safety of ketamine between males and females in the treatment of mood disorders.
PSYCHIATRY RESEARCH
(2022)
Review
Neurosciences
Muhammad Youshay Jawad, Saleha Qasim, Menglu Ni, Ziji Guo, Joshua D. Di Vincenzo, Giacomo d'Andrea, Aniqa Tabassum, Andrea Mckenzie, Sebastian Badulescu, Iria Grande, Roger S. McIntyre
Summary: The scoping review synthesized the current literature on the use of ketamine in bipolar depression. The preliminary evidence suggests that ketamine is a promising treatment with minimal risk and some effectiveness. Future studies should focus on ketamine's role in acute and maintenance treatment phases, as well as its effects on recurrence prevention and anti-suicidal measures.
Article
Multidisciplinary Sciences
Fernanda Schier de Fragaid, Beatriz Souza Lima Wan-Dall, Gabriel Henrique de Oliveira Garcia, Henrique Pandolfo, Adelyne Mayara Tavares da Silva Sequinel, Pedro Alvin, Eduardo Jonson Serman, Vivian Ferreira do Amaral
Summary: The study aimed to observe the frequency of mood disorders and the effectiveness of screening scales for routine use by health professionals during prenatal care in high-risk pregnancies. The results showed a high prevalence of mood disorders in high-risk pregnancies, with the routine use of Edinburgh Postnatal Depression Scale (EPDS) simultaneously to Mood Disorder Questionnaire (MDQ) playing a key role in early diagnosis, counseling, and promotion of perinatal mental health.
Review
Psychiatry
Joseph Biederman, Allison Green, Maura DiSalvo, Stephen V. Faraone
Summary: The study examined the association between polygenic risk scores for bipolar disorder and pediatric mood disorders, finding that these scores were linked to deficits in executive functioning and the diagnosis of attention deficit/hyperactivity disorder (ADHD).
PSYCHIATRY RESEARCH
(2021)
Article
Psychiatry
Yuncheng Zhu, Haifeng Ji, Zhiang Niu, Hongmei Liu, Xiaohui Wu, Lu Yang, Zuowei Wang, Jun Chen, Yiru Fang
Summary: A predictive model was established to differentiate between bipolar disorder and major depressive disorder using clinical biochemical indexes. Female patients may have a higher differentiability with conventional biochemical indexes compared to male patients.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Clinical Neurology
Hu Deng, Fang Wen, Hui Xu, Hanxue Yang, Junjuan Yan, Yi Zheng, Yonghua Cui, Ying Li
Summary: This study is the first nationwide survey on the prevalence of affective disorders among school-attending children and adolescents aged 6-16 in China. The results showed that the total prevalence of affective disorders was 3.212%, with higher rates among females than males and among adolescents compared to children.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Chi-Hung Au, Corine Sau-Man Wong, Chi-Wing Law, Ming-Cheuk Wong, Ka-Fai Chung
GENERAL HOSPITAL PSYCHIATRY
(2019)
Article
Psychiatry
Wing-Fai Yeung, Ka-Fai Chung, Zhang-Jin Zhang, Shi-Ping Zhang, Wai-Chi Chan, Roger Man-Kin Ng, Connie Lai-Wah Chan, Lai-Ming Ho, Branda Yee-Man Yu, Janet Ching-Sum Chau, Novella Chi-Ling Lau, Li-Xing Lao
JOURNAL OF PSYCHIATRIC RESEARCH
(2019)
Article
Obstetrics & Gynecology
F. W. Ngai, PW-C Wong, K-F Chung, P-H Chau, P-W Hui
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2020)
Article
Clinical Neurology
Ka-Fai Chung, Yvonne Patricia Yuan-Ping Poon, Ting-Kin Ng, Chui-Kwan Kan
BEHAVIORAL SLEEP MEDICINE
(2020)
Article
Clinical Neurology
Ka-Fai Chung, Wing-Fai Yeung, Fiona Yan-Yee Ho
SLEEP AND BREATHING
(2020)
Article
Biology
Wing-Fai Yeung, Branda Yee-Man Yu, Yuan-Shan Ho, Fiona Yan Yee Ho, Ka Fai Chung, Regina Lai Tong Lee, Corine Wong, Mei Yuk Lam
CHRONOBIOLOGY INTERNATIONAL
(2019)
Article
Clinical Neurology
Esther Yuet Ying Lau, Kristy Nga Ting Lau, Christian S. Chan, Chia-huei Tseng, Yeuk Ching Lam, Desiree Man-Sik Tse, Wing Yee Cheng, Ka-Fai Chung, Yun Kwok Wing
JOURNAL OF AFFECTIVE DISORDERS
(2020)
Article
Clinical Neurology
Ka-Yan Wong, Ka-Fai Chung, Chi-Hung Au
Summary: The study compared the effectiveness of a single-session cognitive behavioral therapy for insomnia (CBTI) workshop, self-help CBTI, and sleep hygiene education (SHE) workshop among adults with insomnia in the community. Results showed that all interventions had a significant treatment effect on insomnia severity, anxiety and depressive symptoms, and quality of life, with no significant difference between the three groups.
BEHAVIORAL SLEEP MEDICINE
(2021)
Article
Clinical Neurology
Branda Yee-Man Yu, Wing-Fai Yeung, Jason Chun-Sing Lam, Sam Chun-Sum Yuen, Simon Ching Lam, Vincent Chi-Ho Chung, Ka-Fai Chung, Paul Hong Lee, Fiona Yan-Yee Ho, Janice Yuen-Shan Ho
Article
Clinical Neurology
Vincent Wing-Hei Wong, Fiona Yan-Yee Ho, Nga-Kwan Shi, Jerome Sarris, Ka-Fai Chung, Wing-Fai Yeung
Summary: The study found that multi-component lifestyle interventions have a certain alleviating effect on depressive symptoms, but the clinical effect is small, and future research is needed for more comprehensive and individualized interventions.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Fiona Yan-Yee Ho, Wing-Ting Choi, Wing-Fai Yeung, Hiu-Kwan Lam, Wing-Yin Lau, Ka-Fai Chung
Summary: This pilot study found that integrated cognitive behavioral therapy (CBT) and acupressure showed comparable efficacy to pure CBT in treating insomnia symptoms, with additional benefits in improving fatigue symptoms and treatment credibility. Further rigorous studies on a larger scale and longer follow-up are needed to confirm these findings.
Article
Multidisciplinary Sciences
Agnes Ka-Yan Ip, Fiona Yan-Yee Ho, Wing-Fai Yeung, Ka-Fai Chung, Chee H. Ng, Georgina Oliver, Jerome Sarris
Summary: The study demonstrates that a 6-week group-based, integrative lifestyle intervention program is effective in reducing depression, anxiety, stress, and insomnia symptoms in the Chinese population. Further research with larger sample sizes and longer follow-up periods is needed to confirm these findings.
Article
Psychology, Clinical
Vincent Wing-Hei Wong, Fiona Yan-Yee Ho, Nga-Kwan Shi, Jessica Tsz-Yan Tong, Ka-Fai Chung, Wing-Fai Yeung, Chee H. Ng, Gina Oliver, Jerome Sarris
Summary: The study demonstrated the effectiveness of a smartphone-delivered multicomponent lifestyle medicine intervention, Lifestyle Hub, in managing depressive symptoms, anxiety symptoms, and improving quality of life in adults. Health-promoting behaviors and physical activity levels were also significantly increased in the intervention group compared to the control group. However, at the 1-month follow-up, a reduction in health-related quality of life and increase in alcohol intake were observed in the intervention group.
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
(2021)
Article
Sport Sciences
Danny J. Yu, Angus P. Yu, Shirley X. Li, Rachel N. Y. Chan, Daniel Y. Fong, Derwin K. C. Chan, Stanley S. Hui, Ka Fai Chung, Jean Woo, Chenchen Wang, Michael R. Irwin, Parco M. Siu
Summary: This study aims to compare the efficacy and long-term outcomes of Tai Chi and cognitive behavioral therapy for insomnia (CBT-I) in older adults. The participants will be randomly assigned to either the Tai Chi or CBT-I group, and the severity of insomnia will be assessed at 3 months and 15 months. This study is of clinical importance as it supports the use of Tai Chi as an alternative non-pharmacological approach for insomnia treatment.
JOURNAL OF EXERCISE SCIENCE & FITNESS
(2023)
Article
Psychiatry
Ka-Fai Chung, Chit-Tat Lee, Chi-Hung Au, Ka-Yee Kam, Che-Kin Lee, Wing-Fai Yeung, Esther Yuet Ying Lau, Fiona Yan-Yee Ho, Lai-Ming Ho
Summary: This study aimed to evaluate the effectiveness of small-group nurse-administered cognitive behavioural therapy for insomnia (CBTI) as an early intervention for individuals with mood disorders and comorbid insomnia. The results showed that while CBTI did not have a significant effect on the primary outcome, it did lead to improvements in secondary outcomes, including higher depression remission rates and reduced use of anxiolytic medication. These findings suggest that CBTI may be a useful early intervention for enhancing depression remission and reducing medication burden.
EARLY INTERVENTION IN PSYCHIATRY
(2023)