Article
Astronomy & Astrophysics
W. A. Weidmann, K. Werner, J. A. Ahumada, R. A. Pignata, V. Firpo
Summary: Through spectroscopic analysis of nine southern planetary nebulae, we have discovered six hydrogen-rich white dwarfs, two hot hydrogen-deficient PG 1159 stars, and one early O(H) star. This finding significantly increases the number of known white dwarf central stars.
ASTRONOMY & ASTROPHYSICS
(2023)
Article
Neurosciences
Alejandro G. Szmulewicz, Kerollos N. Wanis, Roy H. Perlis, Sonia Hernandez-Diaz, Dost Ongur, Miguel A. Hernan
Summary: This study compared different strategies for managing unresponsive depression and found that using a guidelines-based strategy can increase the probability of remission and reduce the risk of serious adverse events.
BIOLOGICAL PSYCHIATRY
(2023)
Article
Gastroenterology & Hepatology
Charlotte Lloyd, Jessica Leighton, Lin Lee Wong, Anna Goulding, Ann Brownlee, Penney Gray, Emma Culver, Neil Halliday, Doug Thorburn, Michael A. Heneghan, David E. J. Jones, Catherine Exley, Jessica K. Dyson
Summary: This study explored the experiences and needs of patients with autoimmune hepatitis. The findings revealed that patients require more support networks and empowerment, while also facing issues of stigma and fatigue. Patient priorities for improving care include slowing disease progression, avoiding corticosteroids, and minimizing side effects. The study also found that patients are willing to participate in clinical trials.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Clinical Neurology
Nunu Laura Timotheussen Lund, Anja Sofie Petersen, Rolf Fronczek, Jacob Tfelt-Hansen, Andrea Carmine Belin, Tore Meisingset, Erling Tronvik, Anna Steinberg, Charly Gaul, Rigmor Hojland Jensen
Summary: The current treatment for cluster headache is based on trial-and-error methods and lacks specific preventive options. The impact of cluster headache on personal life is significant, with high costs and limited treatment options. There is a need for novel and targeted preventive modalities to suppress the severe pain attacks for people with cluster headache.
JOURNAL OF HEADACHE AND PAIN
(2023)
Article
Neurosciences
Steven M. M. Paul, William Z. Z. Potter
Summary: Unlike most medical fields, the progress in discovering and developing new psychiatric drugs has been slow and disappointing. The majority of currently prescribed drugs for schizophrenia, mood, and anxiety disorders are not significantly more effective than the first generation of drugs introduced over 50 years ago. This article highlights the reasons for this slow progress and discusses research areas that rely on recent advances in neuroscience in order to better understand the biology of these disorders. The potential impact of these research areas is exemplified through recent examples of novel agents that support optimism for the emergence of newer, more effective, and better tolerated psychiatric drugs in the near future. These agents, combined with existing drugs, could greatly improve the functional outcomes for the millions of people who are still disabled by psychiatric disorders.
NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Physics, Multidisciplinary
Zhen-Hua Zhang, Feng-Kun Guo
Summary: The X(3872), a widely studied hadron, has sparked ongoing debates about its internal structure. The introduction of the X atom concept provides insights into the binding energy of the X(3872) and suggests a minimum production rate for the X atom relative to the X(3872) in various decay and collision scenarios.
PHYSICAL REVIEW LETTERS
(2021)
Article
Astronomy & Astrophysics
Valeria Carvalho, Marcio Ferreira, Tuhin Malik, Constanca Providencia
Summary: This study utilizes Bayesian neural networks to directly decipher the internal composition of neutron stars based on their macroscopic properties. By analyzing simulated observations, the proton fraction and sound speed within the neutron star interiors can be inferred. The results demonstrate that Bayesian neural networks successfully recover the composition with reasonable levels of uncertainty.
Article
Physics, Multidisciplinary
Costantino Pacilio, Andrea Maselli, Margherita Fasano, Paolo Pani
Summary: Gravitational-wave measurements from neutron-star binary coalescences can provide insights into the equation of state of dense matter. Current observations have limitations, but future third-generation detectors could greatly enhance our understanding of nuclear matter properties.
PHYSICAL REVIEW LETTERS
(2022)
Article
Chemistry, Inorganic & Nuclear
Weisheng Zhang, Huimin Sun, Zhaopeng Sun, Shuai Liu, Weiwei Huang
Summary: By changing the electrolyte, the storage capacity and cyclic stability of organic electrodes in sodium-ion batteries can be improved. Ionic liquid electrolytes have great potential in enhancing sodium storage behavior.
INORGANIC CHEMISTRY FRONTIERS
(2021)
Editorial Material
Psychology, Biological
Sarah R. Schiavone, Julia G. Bottesini, Simine Vazire
Summary: Improvements in the validity of psychological science require collective efforts from researchers, editors, journals, and publishers. These gatekeepers hold significant power in shaping incentives and must raise their standards to ensure research claims are backed by evidence.
BEHAVIORAL AND BRAIN SCIENCES
(2022)
Review
Pharmacology & Pharmacy
Meifang Zheng, Runping Gao
Summary: This article reviews the mechanisms and potential therapeutic effects of vitamin D and its analogues in the treatment of pancreatic fibrosis, as well as the relationship between vitamin D deficiency and the risk of chronic pancreatitis.
FRONTIERS IN PHARMACOLOGY
(2022)
News Item
Multidisciplinary Sciences
Sara Reardon
Summary: The study indicates that the amyloid-targeting drug candidate has the potential to slow down cognitive decline in certain individuals, but concerns remain regarding its possible side effects.
Editorial Material
Health Care Sciences & Services
Marzyeh Ghassemi, Shakir Mohamed
Summary: Health care is a human process that generates data, and machine learning plays a role in supporting healthier living. The field of machine learning for health needs to consider values and introspect to better understand diseases and support people to live healthier, dignified lives.
NPJ DIGITAL MEDICINE
(2022)
Editorial Material
Biochemistry & Molecular Biology
Annemieke Aartsma-Rus
Summary: Although oligonucleotides have therapeutic potential for patients with unique genetic mutations, the current drug development process does not support the development of personalized therapies.
Article
Multidisciplinary Sciences
Raphael Kazidule Kayambankadzanja, Carl Otto Schell, Isaac Mbingwani, Samson Kwazizira Mndolo, Markus Castegren, Tim Baker
Summary: A study conducted in two hospitals in Malawi revealed a large unmet need for essential treatments for critical illness, such as oxygen therapy and intravenous fluids, among hospitalized patients.
