Article
Oncology
Joseph A. Arthur, Michael Tang, Zhanni Lu, David Hui, Kristy Nguyen, Eden Mae Rodriguez, Tonya Edwards, Sriram Yennurajalingam, Shalini Dalal, Rony Dev, Akhila Reddy, Kimberson Tanco, Ali Haider, Diane D. Liu, Eduardo Bruera
Summary: This study found that approximately 1 in 4 patients receiving opioid therapy for cancer pain had abnormal results in random UDT testing. Random UDT was able to detect abnormalities earlier than targeted UDT. These findings suggest that random UDT may be justified in patients with cancer pain.
Article
Public, Environmental & Occupational Health
Shaden A. Taha, Jordan R. Westra, Mukaila A. Raji, Yong F. Kuo
Summary: The study found that while there was an increasing trend in urine drug testing from 2012 to 2018, annual and baseline urine drug testing rates remained low in 2018, relative to numerous guideline recommendations. This highlights the need for research on better guideline implementation strategies and the effectiveness of urine drug testing on patient outcomes.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2021)
Article
Obstetrics & Gynecology
Jessica A. Peterson, Nathanael C. Koelper, Cara Curley, Sarita R. Sonalkar, Abike T. James
Summary: This study evaluated the effects of a urine drug testing policy in labor and delivery on the number of drug tests performed, racial disparities, testing indications, and neonatal outcomes. The results showed that implementing the policy improved consent for testing, reduced racial disparities, and did not affect neonatal outcomes.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Noelle G. Martinez, Sarah C. M. Roberts, Rachel A. Achu-Lopes, Tirah L. Samura, Dominika L. Seidman, Elisabeth J. Woodhams
Summary: The urine drug test is commonly used in reproductive healthcare, but its application is often biased and stigmatizing, leading to incorrect decisions and negative effects on society and legal systems. This paper proposes a framework to reflect on the use of urine drug tests, including the question being answered, the risks and benefits, alternative decision-making tools, and biases. Using this framework, the paper analyzes three common uses of urine drug tests in abortion and labor and delivery settings.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Oncology
John M. Halphen, Joseph A. Arthur, Soraira Pacheco, Linh M. T. Nguyen, Nikitha N. Samy, Nathaniel R. Wilson, Gregory Sattler, Shane E. Wing, Rex A. D. Paulino, Christine Feng, Pulin Shah, Simbiat Olayiwola, Bradley Cannell, Supriyanka Addimulam, Riddhi Patel, David Hui
Summary: This study examined the use of immunoassay urine drug testing in cancer patients in palliative care clinics. The results showed that 27% of patients tested within the first three visits had aberrant results, with 35% testing positive for cocaine. Non-Hispanic White race, history of illicit drug use, and history of marijuana use were independent predictors of aberrant urine drug testing results.
Article
Law
Melike Aydogdu, Serap Annette Akgur
Summary: The increasing number of problems associated with drug abuse requires new approaches in drug testing systems. This study investigated common tampering methods used by Turkish probationers. It was found that dilution and substitution were the most commonly used methods, with bleach and drain opener causing false-negative results while eye drops had a slight impact on MDMA.
MEDICINE SCIENCE AND THE LAW
(2021)
Article
Public, Environmental & Occupational Health
Vivekanandan Kalaiselvan, Shatrunajay Shukla, Shubhang Arora, Tarani Prakash Shrivastava, Rajeev Singh Raghuvanshi
Summary: This study assesses the performance and outcomes of the public-private partnership in India's Pharmacovigilance Programme, with a focus on quality control, training, and data reporting. The study finds that the public sector has a higher contribution in training and data reporting compared to the private sector.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Agriculture, Dairy & Animal Science
Xavier Manteca Vilanova, Bonnie Beaver, Mette Uldahl, Patricia V. Turner
Summary: This paper presents general guidelines for ensuring the well-being of horses kept for production of biologics. Pharmaceutical products have been derived from horse blood and urine for over a century, with production often occurring in regions with little regulation. Guidance has been developed to support the welfare of horses maintained for these purposes.
Article
Chemistry, Multidisciplinary
Ruijia Huang, Xiaoqing Cai, Jihui Du, Jie Lian, Ping Hui, Minxuan Gu, Feng Li, Jidong Wang, Wenwen Chen
Summary: Delayed use of appropriate antibiotics for super bugs, especially ESBL-producing E.coli and K. pn, has caused significant morbidity and mortality globally. There is an urgent need for rapid on-site antimicrobial susceptibility testing (AST). Inspired by the rapid catalysis of H2O2 by E.coli and K.pn, we developed a plasmonic nanosensor for quick AST. The results can be easily determined with the naked eye or digitized with a smartphone and validated using ultraviolet-visible spectrometry. Our assay achieved high accuracy directly from clinical urine samples infected by E.coli and K.pn, with a short analysis time.
Article
Substance Abuse
Brendan Saloner, Penn Whitley, Eric Dawson, Steven Passik, Adam J. Gordon, Bradley D. Stein
Summary: This study investigated the trends in illicit substance use among M-MOUD patients in the United States and found increasing positivity rates for fentanyl, methamphetamine, and cocaine. However, methadone medication treatment remains an effective intervention for reducing illicit opioid use.
Article
Microbiology
Stephanie Bjerrum, Johanna Ahsberg, Rita Szekely, Japheth Opintan, Margaret Lartey, Maunank Shah, Satoshi Mitarai, Tobias Broger, Morten Ruhwald, Isik Somuncu Johansen
Summary: This study demonstrates that FujiLAM testing performs equally well on spot and early morning urine samples for detecting tuberculosis among people with HIV. Sensitivity can be increased with a two-sample strategy, but at the risk of lower specificity. These findings can inform future guidelines and clinical practices.
MICROBIOLOGY SPECTRUM
(2022)
Article
Business
Jingxian Jiang, Gary D. Ellis, Andrea V. Ettekal, Chad Nelson
Summary: In this study, we used Cronbach and Meehl's construct-validation process to evaluate the true score theory and magnitude scaling approaches to measuring situational engagement. The results supported the hypothesis that magnitude scaling provides stronger evidence of validity, while the true score theory measures showed weak relations with provocation.
JOURNAL OF BUSINESS RESEARCH
(2022)
Article
Chemistry, Analytical
Jaehyeong Park, Nam Hee Kwon, Seon Yeong Kim, Beom Jun Ko, Jin Young Kim
Summary: This study analyzed the correlation between urinary creatinine concentration and urine color to verify the normalcy of urine samples for forensic drug testing. It was found that urine color can be used for urine specimen validity testing, and there is a strong correlation with creatinine concentration.
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY
(2023)
Article
Substance Abuse
Stephen Magura, Miranda J. Lee-Easton, Ruqayyah Abu-Obaid, Pete Reed, Brandi Allgaier, Piyadarsha Amaratunga, Bridget Lorenz-Lemberg, Matthew Levitas, Eric D. Achtyes
Summary: This study compared the results of presumptive drug testing and direct-to-definitive drug testing using urine and oral fluid as test matrices. The confirmed immunoassay (IA) prevalences were higher in urine for most drug classes, except for two drug classes which showed higher prevalences in oral fluid. Overall, the drug detection by direct-to-definitive testing was similar for both urine and oral fluid, but the choice of matrix may depend on the specific drug of interest or concerns about tampering with urine specimens.
DRUG AND ALCOHOL DEPENDENCE
(2023)
Article
Substance Abuse
Sarah Meyers, Elisha M. Wachman
Summary: This case report describes a case where imatinib led to a false-positive amphetamine result on urine drug testing. A 21-year-old female with chronic myelocytic leukemia and history of opioid use disorder reinitiated imatinib therapy during her third trimester of pregnancy, resulting in positive amphetamine test results which were later found to be false through further testing.
JOURNAL OF ADDICTION MEDICINE
(2021)
Review
Substance Abuse
Krzysztof Bogusz, Maciej Kopera, Andrzej Jakubczyk, Elisa M. Trucco, Katarzyna Kucharska, Anna Walenda, Marcin Wojnar
Summary: The lifetime prevalence of alcohol use disorder is higher among individuals with binge eating disorder compared to those without, with a relative risk of more than 1.5 times higher. The prevalence of alcohol use disorder is higher in community samples than in clinical samples, and in studies with a lower proportion of women.
Article
Psychology, Developmental
Elisa M. Trucco, Julie V. Cristello, Matthew T. Sutherland
Summary: Parental attitudes towards e-cigarettes influence adolescents' intentions to use e-cigarettes, while peer norms influence adolescents' positive expectancies of e-cigarette use. Parental attitudes impact adolescent e-cigarette use through intentions, while peer norms have a direct influence on adolescents' positive expectancies.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Article
Medicine, General & Internal
Marta Demkow-Jania, Maciej Kopera, Elisa M. Trucco, Pawel Kobylinski, Anna Klimkiewicz, Malgorzata Abramowska, Anna Mach, Andrzej Jakubczyk
Summary: The study found that substance use disorder moderates the association between personality traits and problematic smartphone use. Neuroticism and openness have different impacts on PSU in the non-SUD group and SUD group. Openness is a significant protective factor against PSU in the SUD group.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychology, Developmental
Elisa M. Trucco, Sarah A. Hartmann
Summary: This review provides an overview of the etiology of adolescent substance use, highlighting the importance of understanding early factors and implementing adaptive interventions.
CHILD DEVELOPMENT PERSPECTIVES
(2021)
Article
Psychology, Developmental
Sarah A. Hartmann, Timothy Hayes, Matthew T. Sutherland, Elisa M. Trucco
Summary: Adolescent temperament dimensions and profiles were found to predict early use of e-cigarettes and alcohol, with differences in predictive value between parent and adolescent reports of temperament profiles.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2021)
Article
Environmental Sciences
Dorota Wolynczyk-Gmaj, Andrzej Jakubczyk, Elisa M. Trucco, Pawel Kobylinski, Justyna Zaorska, Bartlomiej Gmaj, Maciej Kopera
Summary: Alcohol craving is associated with insomnia symptoms, and anxiety symptoms mediate the association between emotional dysregulation and insomnia severity. Insomnia diagnosis moderates the association between emotional dysregulation and anxiety symptoms. Treating anxiety symptoms and emotional dysregulation can help prevent or alleviate insomnia symptoms in individuals with AUD. Treating insomnia in individuals with AUD may also have a positive effect on anxiety symptoms.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Psychology, Developmental
Elisa M. Trucco, Nilofar Fallah-Sohy, Sarah A. Hartmann, Julie Cristello, Jonathan S. Comer, Matthew T. Sutherland
Summary: This study examined the impact of COVID-19-related family conversations and media exposure on youth mental health and found that fears and affected quality of life played a mediating role. Targeted interventions focusing on socialization factors may minimize negative consequences among adolescents following major community trauma.
JOURNAL OF YOUTH AND ADOLESCENCE
(2022)
Article
Psychology, Developmental
Nicole M. Fava, Ryan C. Meldrum, Michelle G. Villar, Robert A. Zucker, Elisa M. Trucco
Summary: This study found that adverse childhood experiences indirectly influence adolescent delinquency through sleep problems and low self-control, while also maintaining a direct association. Early behavioral interventions could help reduce later delinquent behavior.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2022)
Article
Psychology, Developmental
Megan M. Hare, Elisa M. Trucco, Samuel W. Hawes, Michelle Villar, Robert A. Zucker
Summary: While previous studies have identified risk and protective factors of substance use, this study focuses on the reciprocal associations of child conduct problems and parenting practices and behaviors in the prediction of substance use. The results highlight the importance of early intervention and the potential influence of parenting and child factors throughout development in the prevention of substance use.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2023)
Article
Psychology, Developmental
Elisa M. Trucco, Nicole M. Fava, Michelle G. Villar, Mari Kumar, Matthew T. Sutherland
Summary: Collective traumas have a noticeable impact on adolescent well-being, with some at increased risk for mental health problems and others demonstrating resilience. The degree of social isolation plays a role in post-trauma well-being. This study examined the association between maltreatment and internalizing problems during the COVID-19 pandemic, finding that less isolation was related to lower anxiety symptoms for adolescents with pre-pandemic emotional abuse, but higher anxiety and depressive symptoms for those with pre-pandemic physical abuse. The findings highlight the importance of a public health-oriented approach to youth well-being during collective trauma beyond disease mitigation.
JOURNAL OF YOUTH AND ADOLESCENCE
(2023)
Article
Substance Abuse
Elisa M. M. Trucco, Nilofar Fallah-Sohy, Julie V. V. Cristello, Sarah A. A. Hartmann
Summary: This review summarizes theories and empirical work on socialization contexts contributing to substance use among marginalized adolescents. Future directions and recommendations are provided to minimize the perpetuation of racial stereotypes.
CURRENT ADDICTION REPORTS
(2023)
Article
Substance Abuse
Elisa M. Trucco, Nilofar Fallah-Sohy, Sarah A. Hartmann, Julie V. Cristello
CURRENT ADDICTION REPORTS
(2020)
Article
Social Work
Barry Ladis, Elisa M. Trucco, Hui Huang, Barbara Thomlison, Nicole M. Fava
CHILD AND ADOLESCENT SOCIAL WORK JOURNAL
(2020)
Article
Psychology, Developmental
Elisa M. Trucco, Songshan Yang, James J. Yang, Robert A. Zucker, Runze Li, Anne Buu
JOURNAL OF YOUTH AND ADOLESCENCE
(2020)
Article
Health Care Sciences & Services
Sara M. Levens, Sara J. Sagui-Henson, Meagan Padro, Laura E. Martin, Elisa M. Trucco, Nina A. Cooperman, Austin S. Baldwin, Angelos P. Kassianos, Noreen D. Mdege
JMIR RESEARCH PROTOCOLS
(2019)
