Article
Plant Sciences
Vinod Kumar, Soumila Mondal, Anjali Gupta, Pankaj K. Maurya, Rajeshwar P. Sinha, Donat-P Hader, Shailendra P. Singh
Summary: The impact of salinity stress on growth behavior and physiological parameters in Synechococcus elongatus PCC 7942 is dependent on the light environment. High light environment alleviates the negative effect of salinity stress on the organism.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2021)
Article
Marine & Freshwater Biology
Manisha Banerjee, Prakash Kalwani, Dhiman Chakravarty, Beena Singh, Anand Ballal
Summary: The research revealed that low concentrations of selenium did not inhibit the growth and photosynthesis of the cyanobacterium, but higher concentrations led to substantial inhibition. Selenium also impacted the levels of endogenous reactive oxygen species (ROS) and the transcription of photosynthesis-related genes in the cyanobacterium.
AQUATIC TOXICOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Jorge Guio, Maria Teresa Bes, Monica Balsera, Laura Calvo-Begueria, Emma Sevilla, Maria Luisa Peleato, Maria F. Fillat
Summary: FurA is a multifunctional regulator in cyanobacteria that can develop disulfide reductase activity due to lack of a structural zinc ion. The interaction between FurA and the type m thioredoxin TrxA was confirmed through in vitro and in vivo studies, suggesting TrxA as a redox partner that modulates FurA performance in facilitating interactions with different ligands.
Article
Environmental Sciences
Karolina Czarny, Barbara Krawczyk, Dominik Szczukocki
Summary: The toxic effects of bisphenol analogues, both individually and in combination, on cyanobacteria need further investigation. Different bisphenol analogues exhibit varying levels of toxicity to cyanobacteria, with mixtures potentially showing stronger toxic effects than bisphenol A.
Article
Biochemistry & Molecular Biology
Benjamin L. Springstein, Dennis J. Nurnberg, Christian Woehle, Julia Weissenbach, Marius L. Theune, Andreas O. Helbig, Iris Maldener, Tal Dagan, Karina Stucken
Summary: Filament-forming proteins play crucial roles in cellular processes such as cell division and growth. Two novel coiled-coil-rich proteins in the filament-forming cyanobacterium Anabaena assemble into heteropolymers and function in maintaining the multicellular shape. Their function is achieved through cooperation with other proteins to stabilize the cell shape.
Article
Microbiology
Loknath Samanta, Karin Stensjo, Peter Lindblad, Jyotirmoy Bhattacharya
Summary: This study investigates the tolerance of filamentous cyanobacteria to hydrogen peroxide (H2O2) and finds that different strains have different levels of tolerance, which is important for the selection and use of strains in biotechnological applications.
ARCHIVES OF MICROBIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Irshad Ahamad, Nafe Aziz, Almaz Zaki, Tasneem Fatma
Summary: This study successfully synthesized AgNPs using Anabaena variabilis-mediated approach, demonstrating excellent antibacterial and antifungal activity. Combined with standard antibiotics and antifungal agents, AgNPs showed significant synergistic effects.
JOURNAL OF APPLIED PHYCOLOGY
(2021)
Article
Microbiology
Brenda S. Pratte, Teresa Thiel
Summary: This study identified unique and overlapping functions of two homologous transcriptional activators, CnfR1 and CnfR2, in regulating two distinct nitrogenase systems in Anabaena variabilis. CnfR1 was found to be promiscuous in activating both nitrogenase systems, while CnfR2 relied on additional cellular factors to activate only one nitrogenase system.
MICROBIOLOGY SPECTRUM
(2021)
Article
Microbiology
Bethan Kultschar, Ed Dudley, Steve Wilson, Carole Anne Llewellyn
Summary: UV-A exposure significantly influences metabolite levels in C. fritschii, showing an overall increase within 24 hours. UV-A is more similar to PAR compared to UV-B, indicating the importance of amino acids glutamate, phenylalanine, and leucine in UV stress response. Palmitic and stearic acids exhibit positive log2 fold-change in UV-A and PAR experiments, while showing negative log2 fold-change in UV-B experiments, suggesting the more harmful effect of UV-B on primary metabolism.
Article
Biochemistry & Molecular Biology
Prashant R. R. Singh, Jainendra Pathak, Rajneesh, Haseen Ahmed, Donat -P. P. Haeder, Rajeshwar P. Sinha
Summary: Cyanobacteria use circadian rhythms to cope with daily light fluctuations and the dark phase plays a significant role in protecting them from the negative impact of continuous light exposure. This study provides insights into the physiological responses of cyanobacteria to changing light environments.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2023)
Article
Biology
Md. Shakir Ahammed, Md. Abdul Baten, Muhammad Aslam Ali, Shahin Mahmud, Md. Sirajul Islam, Bhim Sen Thapa, Md. Aminul Islam, Md. Alim Miah, Tanmoy Roy Tusher
Summary: This study investigated the ability of microalgae and cyanobacteria to remove pollutants, especially heavy metals, from polluted river water. The results showed that both microalgae and cyanobacteria significantly reduced the pollutants and heavy metal concentrations. However, their efficiency in pollutant removal varied depending on the species.
Article
Microbiology
Ritu Garg, Iris Maldener
Summary: Anabaena variabilis is a filamentous cyanobacterium capable of differentiating into specialized cells, heterocysts and akinetes, to survive under different stress conditions. Both cell types are characterized by the presence of a thick multilayered envelope, which includes a glycolipid layer. Studies have shown that heterocysts and akinetes use a glycolipid of identical chemical composition in their special envelopes, highlighting the importance of the glycolipid layer for their functions.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Shimaa M. El Shafay, Ahmed Gaber, Walaa F. Alsanie, Mostafa E. Elshobary
Summary: The study aimed to improve biomass and biochemical constituents, especially lipid production, of Anabaena variabilis and Nostoc muscorum by formulating an optimal growth condition using various concentrations of nutrients. A. variabilis was chosen for biodiesel production due to its superior lipid and protein accumulation, while N. muscorum showed the highest carbohydrate content.
Article
Food Science & Technology
Olga A. Koksharova, Ivan O. Butenko, Olga V. Pobeguts, Nina A. Safronova, Vadim M. Govorun
Summary: The study demonstrates that BMAA treatment results in imbalance of energy and metabolite levels in diazotrophic cyanobacterial cells, leading to upregulation of stress-activated proteins and affecting the expression of nitrogenase subunits involved in nitrogen fixation. These findings provide new insights into the ecological impact of BMAA on microalgal communities.
Article
Marine & Freshwater Biology
Zi-Qian Wang, Cheng-Cai Zhang
Summary: In this study, the authors demonstrate that the system responsible for modifying ANN-decoding tRNAs is involved in the sensitivity of cyanobacteria to the environmental neurotoxin BMAA. The study also reveals that both BMAA and inactivation of the t(6)A biosynthesis pathway affect translational fidelity and ribosome assembly. BMAA-resistant mutants screening is an effective method for gaining insight into the toxic mechanisms of BMAA.
AQUATIC TOXICOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Haseen Ahmed, Jainendra Pathak, Rajneesh, Piyush K. Sonkar, Vellaichamy Ganesan, Donat-P. Haeder, Rajeshwar P. Sinha
Summary: The study found that exposure to ultraviolet radiation inhibited the growth and chlorophyll a content of hot spring cyanobacteria, but increased total carotene content. Additionally, the efficiency of photosystem II and electron transport rate decreased, while non-photochemical quenching increased and photochemical quenching decreased under certain light conditions. Reactive oxygen species levels significantly increased under specific exposure conditions, and the antioxidant machinery showed significant enhancement. The discovery of a mycosporine-like amino acid, shinorine, and its electrochemical and antioxidant properties were also highlighted in the study.
Review
Environmental Sciences
Pankaj Kumar Maurya, Soumila Mondal, Vinod Kumar, Shailendra Pratap Singh
Summary: By 2050, the total global population is estimated to exceed 9 x 10(3) million, posing a challenge in providing energy and clean environment. Population growth leads to changes in land use and increased greenhouse gas emissions. Energy consumption affects the quality of the environment, resulting in ocean acidification and other environmental fluctuations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Rajneesh, Soumila Mondal, Jainendra Pathak, Prashant R. Singh, Shailendra P. Singh, Rajeshwar P. Sinha
Summary: Photolyases are enzymes that use light to repair UV-induced damage. By analyzing the amino acid sequences of cyanobacterial genomes, five classes of photolyases were identified. The distribution of these classes varied depending on the habitat of the organisms. Novel binding sites were also discovered, providing insights for the development of efficient photolyase-based formulations.
CANADIAN JOURNAL OF MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Amit Gupta, Niharika Sahu, Ashish P. Singh, Vinay Kumar Singh, Suresh C. Singh, Vijay J. Upadhye, Alen T. Mathew, Rajnish Kumar, Rajeshwar P. Sinha
Summary: This study identified potential inhibitors against the main protease (Mpro) of SARS-CoV-2 through virtual screening and molecular docking. Among the identified hits, usnic acid showed stability and effectiveness in inhibiting SARS-CoV-2 Mpro. Therefore, usnic acid, variolaric acid, and gyrophoric acid could serve as lead compounds for the development of antiviral drugs targeting SARS-CoV-2.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Niharika Sahu, Sonal Mishra, Minu Kesheri, Swarna Kanchan, Rajeshwar P. Sinha
Summary: The study identified cyanobacterial photoprotective compounds as potential inhibitors against ACE2, a druggable target of SARS-CoV-2. Molecular docking and other analyses indicated that mycosporine-glycine-valine and shinorine have the potential to be potent ACE2 inhibitors and can be explored further for COVID-19 treatment.
INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Soumila Mondal, Shailendra P. Singh
Summary: This study conducted a comparative analysis of the structure and amino acid sequences of 65 Trxs and 88 Grxs from 12 organisms in three domains of life. The results showed that despite the diversity in amino acid composition, both Trxs and Grxs conserved functionally and structurally important residues. Substitutions during evolution preferred amino acids with similar chemical properties. Trxs and Grxs showed greater differences in eukaryotes compared to prokaryotes, with opposite surface charges but uncharged active sites. The study also supported the endosymbiotic origins of chloroplast and mitochondria.
Article
Plant Sciences
Pankaj K. Maurya, Soumila Mondal, Vinod Kumar, Shailendra P. Singh
Summary: Cyanobacteria, specifically Synechococcus elongatus PCC 7942, show varying responses to different light wavelengths, with green and blue light negatively affecting their fitness and growth but increasing lipid content and changing cell morphology.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2023)
Article
Environmental Sciences
Pankaj K. Maurya, Vinod Kumar, Soumila Mondal, Shailendra P. Singh
Summary: This study focuses on a black-colored soil crust composed of a cyanobacterium called Oscillatoria sp. Malviya-1, which has the unique ability to utilize various light spectra for photosynthesis. The cyanobacterium adjusts its light-harvesting machinery and produces sunscreens to adapt to different light conditions and ultraviolet radiation.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biology
Soumila Mondal, Shailendra P. Singh
Summary: This article presents a method for high-throughput oxidative stress measurement using DCFH-DA and FCM, which is applicable to both unicellular and filamentous cyanobacteria. By optimizing cell number, dye concentration, and FCM parameters, reactive oxygen species (ROS) can be quantified. This FCM-based method enables the high-throughput measurement of ROS in a large population of bacterial cells.
Article
Nanoscience & Nanotechnology
Vivek K. Sharma, Prateeksha, Shailendra P. Singh, Brahma N. Singh, Chandana Rao, Saroj K. Barik
Summary: The study demonstrates that CUR-encapsulated polysaccharide nanoparticles (CUR-PS-NPs) effectively inhibit cytokine storm induced by SARS-CoV-2 virus infection, leading to reduced lung and liver injuries. The mechanism of action involves the reduction of NF-kappa B/MAPK signaling, resulting in decreased cytokine release.
ACS APPLIED BIO MATERIALS
(2022)
Article
Chemistry, Applied
Jainendra Pathak, Deepak Kumar, Deepak K. Singh, Haseen Ahmed, Vinod K. Kannaujiya, Rajeshwar P. Sinha
Summary: Enhanced ultraviolet radiation and increased salinity negatively impact the productivity of photoautotrophs. Cyanobacteria, known for their ability to survive in high UV environments, are valuable for studying plant adaptations to salt and UV stress. Research on the effects of salinity, radiation, and UVR on two cyanobacteria species showed increased ROS production and significant protein and pigment profile changes under stress conditions.
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY
(2022)
Proceedings Paper
Computer Science, Information Systems
Rajneesh Kumar Singh, S. Pratap Singh, Shailesh Tiwari
Summary: High node density is essential for enabling various applications of AWNS, while energy harvesting is a key requirement. Cooperative beam selection based on RUB can enhance energy harvesting performance. Statistical measures for harvested energy, including analytical expressions for CDF and Pout, as well as the impact of factors such as number of antennas and interference power, have been presented in this study.
2021 11TH INTERNATIONAL CONFERENCE ON CLOUD COMPUTING, DATA SCIENCE & ENGINEERING (CONFLUENCE 2021)
(2021)
Article
Computer Science, Information Systems
Shailendra Pratap Singh, Vibhav Prakash Singh, Ashok Kumar Mehta
Summary: A new variant of differential evolution algorithm, which incorporates a homeostasis adaption based mutation operator, is proposed in this paper to improve the performance of DE algorithm for cost estimation in software development. The main objective of this algorithm is to accurately predict and minimize errors in fewer iterations to optimize tuning parameters.
JOURNAL OF KING SAUD UNIVERSITY-COMPUTER AND INFORMATION SCIENCES
(2021)
Article
Multidisciplinary Sciences
Himani Patel, Anil K. Pokharia, N. Nihildas, Niraj Rai, Rajeshwar P. Sinha
Summary: The study of macrobotanical remains at the Rithi Ranjana site in Vidarbha, Maharashtra, India, reveals that staple food-grains were rice, barley, and wheat. Evidence of fruits gathered by ancient settlers and the presence of winter and summer crops were also found, indicating the cultural period of Early Iron Age at the site.