期刊
PROTOPLASMA
卷 251, 期 3, 页码 699-702出版社
SPRINGER WIEN
DOI: 10.1007/s00709-013-0544-5
关键词
Intercellular transfer; Extracellular vesicles; Exosomes; Microvesicles; DiO; Cholera toxin
This communication reports the first experimental evidence that in the bladder cancer model, membranous components labelled with the DiO dye and the cholera toxin subunit B can be transported from highly malignant (T24) to non-malignant (RT4) cells by extracellular vesicles. Taking into account the presence of stable membranous nanostructures found by scanning electron microscopy, we suggest a possible uptake mechanism in recipient cells through fusion with highly curved membranous regions.
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