Article
Engineering, Environmental
Yanfang Zhao, Rabah Boukherroub, Lu Liu, Huizhi Li, Ru-Song Zhao, Qin Wei, Xiang Yu, Xiangfeng Chen
Summary: This study demonstrates the effective utilization of boron nitride quantum dots as an inorganic matrix in MALDI-MS & MSI for BPA analysis. The method allows non-destructive and in situ mapping of BPA in environmental water and plastic products, and detects BPA at nanomolar level.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Applied
Tokuma Fukuoka, Sayaka Nakamura, Tomotake Morita, Takayuki Ohmura, Masahiro Kotani, Yasuhide Naito, Hiroaki Sato
Summary: The study successfully detected various lower molecular weight products in the extract of a glycolipid BS producer using a matrix-free SALDI-MS analysis method, with good sensitivity.
JOURNAL OF OLEO SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Marco Roverso, Roberta Seraglia, Raghav Dogra, Denis Badocco, Silvia Pettenuzzo, Luca Cappellin, Paolo Pastore, Sara Bogialli
Summary: This study evaluated the use of single-walled carbon nanohorns (SWCNH) as a specific surface for Surface-Assisted Laser Desorption Ionization (SALDI) analysis. The optimized method provided rapid analysis of amino acids and lipids, and accurately determined the composition of fatty acids in olive oil samples without any sample treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Sara A. Al-Sayed, Mohamed O. Amin, Entesar Al-Hetlani
Summary: In this study, a matrix-free approach based on magnetic nanoparticles was proposed for the analysis of contaminated fingermarks using SALDI-MS. The method allows for the analysis of both the fingermarks and the cosmetic products without sample pretreatment, and the stability and recovery of the components from different surfaces were investigated.
Article
Chemistry, Analytical
Alexander Gorbunov, Alexander Bardin, Semyon Ilyushonok, Jacob Kovach, Artem Petrenko, Nikolai Sukhodolov, Konstantin Krasnov, Nikolai Krasnov, Ivan Zorin, Alexander Obornev, Vladimir Babakov, Andrey Radilov, Ekaterina Podolskaya
Summary: Metabolic conversion of drugs to chemically reactive products, known as bioactivation, is considered important in adverse drug reactions. UV/TiO2 photocatalytic oxidation (UV/TiO2-PCO) can be used for rapid screening of candidate drugs for reactive metabolite formation. A novel 96-well on target UV/TiO2-photocatalytic microreactor setup (PC mu R96) was developed and evaluated, allowing for drug metabolism simulation and sample preparation directly on a MALDI target. Amodiaquine oxidation products and their protein adducts were obtained and identified using PC mu R96.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Zhaoyan Yang, Yuhui Dong, Shenfei Zong, Lang Li, Kuo Yang, Zhuyuan Wang, Haibo Zeng, Yiping Cui
Summary: This study explores water-dispersed perovskite CsPbBr3 nanocrystals as a fluorophore for single-molecule localization microscopy (SMLM). The CsPbBr3 NCs fabricated by a one-step mechanochemical method exhibit ultrahigh photoluminescence quantum yield (PLQY), frequent fluorescence blinking, proper duty cycle, and long-term photostability, achieving an extremely high location precision of around 3 nm. The spatial resolution of SMLM images depends on the size of CsPbBr3 NCs, with a size of approximately 23 nm providing clear distinction of closely spaced NCs. Furthermore, the CsPbBr3 NCs can retain their excellent fluorescence characteristics even after surface biofunctionalization, expanding the possibilities for perovskite quantum dot-based SMLM in bioimaging.
Article
Chemistry, Physical
Jingxuan Pei, Yibo Sun, Xiang Yu, Zhenfei Tian, Shuting Zhang, Songbo Wei, Yanfang Zhao, Rabah Boukherroub
Summary: The development of a reliable sensing strategy combining surface-enhanced Raman scattering (SERS) and surface-assisted laser desorption/ionization-mass spectrometry (SALDI-MS) is of significant interest for distinguishing cysteine enantiomers in body fluid and understanding their physiological roles and toxicity hazards.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Nadia Nunes, Iva Popovic, Elder Abreu, Dina Maciel, Joao Rodrigues, Juan Soto, Manuel Algarra, Marijana Petkovic
Summary: The detection of RuCp complex in human urine using MALDI-TOF MS without prior purification or removal of inorganic salts was successfully achieved. Different acquisition conditions showed varying levels of sensitivity and precision, with the matrix-free approach and DHB matrix demonstrating the highest sensitivity and precision in urine samples. Higher sensitivity of matrix-free MALDI detection of RuCp can be achieved by adding carbon dots to the urine solution.
Article
Engineering, Environmental
Zifang Peng, Wenfen Zhang, Dan Yin, Xu Zhang, Shuo Liu, Wuduo Zhao, Jian Mao, Yanhao Zhang, Jianping Xie
Summary: A novel magnetic single-layer nano-MXene (SNM@Fe3O4) with small size, high surface area, abundant active sites, and excellent energy absorption/transfer capability was prepared. It was found that SNM@Fe3O4 could serve as a highly effective adsorbent for enrichment and a new surface-assisted laser desorption/ionization-time of flight-mass spectrometry (SALDI-TOF-MS) matrix for rapid analysis of p-Phenylenediamine (PPD) antioxidants in water samples. The SNM@Fe3O4-based SALDI-TOF-MS approach showed good linearity, high sensitivity, and qualified precision for the detection of PPDs in water.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Applied
Rocio Galindo-Lujan, Laura Pont, Victoria Sanz-Nebot, Fernando Benavente
Summary: This study presents a method using mass spectrometry to analyze quinoa proteins, allowing for accurate identification of different commercial quinoa varieties. The developed method provides reliable protein fingerprints for classification of quinoa products based on their protein profiles.
Review
Biochemistry & Molecular Biology
Madhuri Jayathirtha, Emmalyn J. Dupree, Zaen Manzoor, Brianna Larose, Zach Sechrist, Anca-Narcisa Neagu, Brindusa Alina Petre, Costel C. Darie
Summary: The human genome consists of around 30,000 genes, making humans slightly more complex than worms or flies. However, the complexity of humans mainly comes from the diverse proteins encoded by these genes, as well as the production of multiple proteins through alternative splicing and tissue-dependent expression. Post-translational modifications in proteins significantly increase the number of gene products or protein isoforms.
CURRENT PROTEIN & PEPTIDE SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Sergio G. Hernandez-Leon, Jose Andre-i Sarabia Sainz, Gabriela Ramos-Clamont Montfort, Jose Angel Huerta-Ocampo, Martha Nydia Ballesteros, Ana M. Guzman-Partida, Maria del Refugio Robles-Burgueno, Luz Vazquez-Moreno
Summary: This study utilized functionalized core-shell silica nanoparticles to isolate potential biomarkers from urine samples of adults with different weights. Through mass spectrometry and database searching, 36 proteins were successfully identified and grouped into different clusters, with gender-specific proteins identified and differences in protein abundance observed in urine from both genders. This new approach demonstrates promise for the identification of urinary biomarkers.
Review
Biochemistry & Molecular Biology
Nhi Le, Min Zhang, Kyoungtae Kim
Summary: In this mini-review, the impacts of quantum dots on mammalian organisms, fungal organisms, and plants at the cellular, tissue, and organismal level are summarized, alongside their interactions with biological structures. The findings suggest that quantum dots may have toxic effects on the environment and biological systems. This review aims to provide a better understanding of the current research status of quantum dots, identify knowledge gaps in the field, and offer insights for future research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Analytical
Yuanxia Lv, Xiaohuan Qin, Kun Hu, Fanggui Ye, Shulin Zhao
Summary: This study introduces a SALDI-TOF MS method using MP-HOFs for the analysis of PQ and CQ in real samples. The method demonstrated high selectivity and sensitivity in detecting the pesticides.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Physical
Mervat Ibrahim, Moataz G. Fayed, Saad G. Mohamed, Zhen Wen, Xuhui Sun, Hani Nasser Abdelhamid
Summary: This study introduces a method for synthesizing covalent organic frameworks/graphitic carbon nitride nanocomposites and preparing nitrogen-doped carbon and nitrogen-doped carbon/g-C3N4 materials through carbonization reaction. These materials can be used for supercapacitors and lithium-ion batteries, exhibiting high specific capacitance and good energy. The asymmetric supercapacitor device shows high energy and power, and the nitrogen-doped carbon/g-C3N4 electrode also demonstrates high discharge capacity.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Chemistry, Applied
Mahmoud R. Saleh, Haitham M. El-Bery, Hani Nasser Abdelhamid
Summary: A wet-incipient impregnation method was used to synthesize hierarchical porous bimetallic (Co, Zn)-zeolitic imidazolate frameworks (ZIF-8)/TiO2 for efficient photocatalytic water splitting. Co@ZIF-8/TiO2 exhibited significantly higher photocatalytic efficiency than TiO2, with a hydrogen generation rate of 13 mmol·h(-1)·g(-1) and a 151-fold increase in catalytic performance. The hierarchical porous structure of Co@ZIF-8 facilitated charge transfer and provided efficient transport channels. This study demonstrates the potential of hierarchical porous metal-organic frameworks (MOFs) as support and promoter in photocatalytic applications of TiO2.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Applied
Hani Nasser Abdelhamid, Ghada Abd-Elmonsef Mahmoud
Summary: In this study, copper-based metal-organic frameworks (MOFs) were used to synthesize copper oxide (CuO) embedded into carbon (CuO@C), which displayed high antifungal activity against four economic postharvest plant pathogens. The CuO@C nanoparticles inhibited the growth of the fungal species and decreased their enzyme activity, reducing the potentiality of fruit disease. The successful formation of CuO@C nanoparticles was confirmed using various characterization techniques.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Hani Nasser Abdelhamid
Summary: One-pot co-precipitation method for synthesizing microporous-mesoporous zeolitic imidazolate frameworks-8 (ZIF-8) crystals, using organic dyes as target molecules, was reported. The crystal growth involves an intermediate phase of zinc hydroxyl nitrate nanosheets, allowing the adsorption of the dyes. The materials showed potential for CO2 adsorption and ATP biosensing.
DALTON TRANSACTIONS
(2023)
Article
Green & Sustainable Science & Technology
Amal Abdelhaleem, Hani Nasser Abdelhamid, Mona G. Ibrahim, Wei Chu
Summary: The study utilized a copper-based metal-organic framework-derived catalyst for the photodegradation of paracetamol, observing a unique enhancement effect at extreme pH 9.9 and identifying two new substances among eight intermediates.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Chemistry, Inorganic & Nuclear
Walid Sharmoukh, Hani Nasser Abdelhamid
Summary: A metal-organic framework (MOF) of cerium (Ce) ions and 4,4 ',4 ''-nitrilotribenzoic acid linker was synthesized via a hydro thermal method. The Ce-MOF showed Fenton-like properties and displayed excellent catalytic oxidation activity for various organic compounds and water pollutants. It exhibited high efficiency in the oxidative degradation of dyes and could be recycled multiple times without significant loss of catalytic performance.
JOURNAL OF CLUSTER SCIENCE
(2023)
Article
Chemistry, Applied
Hani Nasser Abdelhamid
Summary: Metal-organic frameworks (MOFs) have shown great potential for industrial applications but current synthesis processes limit their use due to the powder form. A solvothermal method was used to grow copper-based MOFs onto a cotton textile, creating a material called CuBDC@Textile. CuBDC@Textile demonstrated excellent vapor sensing properties and high adsorption capacity for pyridine. This dual-functional material holds promise for further research on MOFs in textile applications.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Materials Science, Ceramics
Numa A. A. Althubiti, T. A. Taha, A. A. Azab, Hani Nasser Abdelhamid
Summary: The use of solid-state materials such as sodium borohydride for hydrogen storage and release can meet the requirements of the "Hydrogen Economy". This study investigated ZnO-based materials as catalysts for hydrogen release through the hydrolysis of NaBH4. The synthesis method produced nanocomposites consisting of ZnO-xTiO(2) and ZnO-xCeO(2) (x = 5 wt.% or 10 wt.%). Characterization techniques confirmed the phase purity and optical properties of the materials. The materials exhibited a high hydrogen generation rate and different activation energies.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Physical
Hani Nasser Abdelhamid, Islam M. A. Mekhemer, Abdel-Aal M. Gaber
Summary: In this study, benzimidazole derivatives were successfully synthesized through photocatalytic synthesis using a solid-state acid catalyst ZrOSO4@C. The reaction, which allowed for condensation and cyclization in a single vessel, resulted in high yield (77-98%) and high purity of the benzimidazoles. The catalyst showed improvement in the synthesis of various benzimidazole derivatives using a wide range of aromatic aldehydes and heterocycles.
MOLECULAR CATALYSIS
(2023)
Article
Energy & Fuels
Moushira Saleh, Hani Nasser Abdelhamid, Dina M. Fouad, Haitham M. El-Bery
Summary: The use of light radiation to split water into hydrogen gas has great potential for green hydrogen production. A comparative study was conducted on the photocatalytic activity of TiO2 nanocomposites with two co-catalysts, Pt or Cu nanocrystals, using different synthesis methods. The study found that the deposition technique of the co-catalyst has a significant influence on the efficiency of photocatalysis for hydrogen production.
Article
Chemistry, Inorganic & Nuclear
Hani Nasser Abdelhamid, Sahar Sultan, Aji P. Mathew
Summary: 3D printing of cellulose/leaf-like zeolitic imidazolate frameworks (CelloZIF-L) allows for the creation of structures with high adsorption efficiency, capable of adsorbing carbon dioxide and heavy metals.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Dimitrios Georgouvelas, Hani Nasser Abdelhamid, Ulrica Edlund, Aji P. Mathew
Summary: In this study, nanocellulose/alginate composite hydrogel beads were successfully prepared and modified with in situ TEMPO-mediated oxidation. The modified beads exhibited improved adsorption efficiency and water flux, making them promising candidates for large-volume, high flux water treatment.
NANOSCALE ADVANCES
(2023)
Article
Engineering, Environmental
Ayat Badry Aly Abdellatif, Haitham M. El-Bery, Hani Nasser Abdelhamid, Sahar A. El-Gyar
Summary: This study reported a method of encapsulating thiourea and D-Glucose-6 -phosphate disodium salt dihydrate into zeolitic imidazolate frameworks, and tested their potential applications as catalysts in hydrogen generation and degradation of organic dyes.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Fatma El-Zahraa A. Abd El-Aziz, Noha Esmael Ebrahem, Hani Nasser Abdelhamid
Summary: This study examined the toxic effect of two Zinc-based metal-organic frameworks (MOFs) on carrions and arthropods found in decomposing carrions. The results showed an increase in zinc content over time. This research provides important biological information that could contribute to understanding the environmental impact of MOF materials' toxic levels.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Environmental
Ahmed F. Abdel-Magied, Radwa M. Ashour, Le Fu, Moataz Dowaidar, Wei Xia, Kerstin Forsberg, Hani Nasser Abdelhamid
Summary: The study synthesized two magnetic metal-organic frameworks and investigated their adsorption capacities for Cd(II) and Pb(II). The adsorption efficiency is strongly dependent on the pH of the solution, and the process follows a pseudo-second-order model and fits the Langmuir isotherm model.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)