4.5 Article

The Gel Electrophoresis Markup Language (GelML) from the Proteomics Standards Initiative

期刊

PROTEOMICS
卷 10, 期 17, 页码 3073-3081

出版社

WILEY
DOI: 10.1002/pmic.201000120

关键词

Bioinformatics; Database; Data standard; Gel electrophoresis; Ontology

资金

  1. BBSRC [BB/G010781/1]
  2. NIH/CTSA [1UL1RR024148]
  3. Biotechnology and Biological Sciences Research Council [BB/G010781/1] Funding Source: researchfish
  4. BBSRC [BB/G010781/1] Funding Source: UKRI

向作者/读者索取更多资源

The Human Proteome Organisation's Proteomics Standards Initiative has developed the GelML (gel electrophoresis markup language) data exchange format for representing gel electrophoresis experiments performed in proteomics investigations. The format closely follows the reporting guidelines for gel electrophoresis, which are part of the Minimum Information About a Proteomics Experiment (MIAPE) set of modules. GelML supports the capture of metadata (such as experimental protocols) and data (such as gel images) resulting from gel electrophoresis so that laboratories can be compliant with the MIAPE Gel Electrophoresis guidelines, while allowing such data sets to be exchanged or downloaded from public repositories. The format is sufficiently flexible to capture data from a broad range of experimental processes, and complements other PSI formats for MS data and the results of protein and peptide identifications to capture entire gel-based proteome workflows. GelML has resulted from the open standardisation process of PSI consisting of both public consultation and anonymous review of the specifications.

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