Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide

Histidine 14 Modulates Membrane Binding and Neurotoxicity of the Alzheimer's Disease Amyloid-β Peptide

(2017) Danielle G. Smith et al.   JOURNAL OF ALZHEIMERS DISEASE

Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation

(2013) Luke A. Miles et al.   Scientific Reports

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Iron(II) Binding to Amyloid-β, the Alzheimer’s Peptide

(2011) Fatima Bousejra-ElGarah et al.   INORGANIC CHEMISTRY

Crystal Structure of the Amyloid-  p3 Fragment Provides a Model for Oligomer Formation in Alzheimer's Disease

(2011) V. A. Streltsov et al.   JOURNAL OF NEUROSCIENCE

Substantial Contribution of the Two Imidazole Rings of the His13−His14 Dyad to Cu(II) Binding in Amyloid-β(1−16) at Physiological pH and Its Significance

(2011) Byong-kyu Shin et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Protonation, Tautomerization, and Rotameric Structure of Histidine: A Comprehensive Study by Magic-Angle-Spinning Solid-State NMR

(2011) Shenhui Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assignment of PolyProline II Conformation and Analysis of Sequence – Structure Relationship

(2011) Yohann Mansiaux et al.   PLoS One

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Minimal Zn 2+ Binding Site of Amyloid- β

(2010) Philipp O. Tsvetkov et al.   BIOPHYSICAL JOURNAL

Modeling the Cu+Binding in the 1−16 Region of the Amyloid-β Peptide Involved in Alzheimer’s Disease

(2010) Sara Furlan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Importance of dynamical processes in the coordination chemistry and redox conversion of copper amyloid-β complexes

(2009) Christelle Hureau et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Pleomorphic Copper Coordination by Alzheimer’s Disease Amyloid-β Peptide

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alanine-2 Carbonyl is an Oxygen Ligand in Cu2+Coordination of Alzheimer’s Disease Amyloid-β Peptide − Relevance to N-Terminally Truncated Forms

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Germline humanization of a murine Aβ antibody and crystal structure of the humanized recombinant Fab fragment

(2009) Remy Robert et al.   PROTEIN SCIENCE

Kinetic screening of antibody–Im7 conjugates by capture on a colicin E7 DNase domain using optical biosensors

(2008) Ralf J. Hosse et al.   ANALYTICAL BIOCHEMISTRY

Structural Studies of Copper(I) Complexes of Amyloid-β Peptide Fragments: Formation of Two-Coordinate Bis(histidine) Complexes

(2008) Richard A. Himes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Structure of the Amyloid-β Peptide High-Affinity Copper II Binding Site in Alzheimer Disease

(2008) Victor A. Streltsov et al.   BIOPHYSICAL JOURNAL

Different Hydration Changes Accompanying Copper and Zinc Binding to Amyloid β-Peptide: Water Contribution to Metal Binding

(2008) Haijia Yu et al.   CHEMBIOCHEM

Substrate mediated reduction of copper-amyloid-β complex in Alzheimer’s disease

(2008) Victor A. Streltsov et al.   CHEMICAL COMMUNICATIONS

Amyloid-β–Anti-Amyloid-β Complex Structure Reveals an Extended Conformation in the Immunodominant B-Cell Epitope

(2008) Luke A. Miles et al.   JOURNAL OF MOLECULAR BIOLOGY

The Amyloid-β Peptide of Alzheimer’s Disease Binds CuIin a Linear Bis-His Coordination Environment: Insight into a Possible Neuroprotective Mechanism for the Amyloid-β Peptide

(2008) Jason Shearer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Aggregation and catabolism of disease-associated intra-Aβ mutations: reduced proteolysis of AβA21G by neprilysin

(2008) Vicki Betts et al.   NEUROBIOLOGY OF DISEASE

Platinum-based inhibitors of amyloid-  as therapeutic agents for Alzheimer's disease

(2008) K. J. Barnham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers

(2008) R. Robert et al.   PROTEIN ENGINEERING DESIGN & SELECTION