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Summary: GO-CAMs combine individual gene product associations with cellular components, molecular functions, and biological processes into causally linked activity flow models. The software tool Pathways2GO converts the entire set of Reactome pathways into GO-CAMs, providing standard GO annotations and quality control for the bioinformatics community. This conversion ensures a seamless integration between Reactome and GO resources.
Review
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Summary: PANTHER is a user-focused knowledgebase that stores results of extensive phylogenetic reconstruction pipelines and provides manual review and annotation of function evolution events, aiding in protein sequence analysis tasks.