Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values

Effect of Charge Regulation and Ion–Dipole Interactions on the Selectivity of Protein–Nanoparticle Binding

(2014) Fernando Luís Barroso da Silva et al.   LANGMUIR

Electrostatic Effects in Filamentous Protein Aggregation

(2013) Alexander K. Buell et al.   BIOPHYSICAL JOURNAL

Effect of Metal Loading and Subcellular pH on Net Charge of Superoxide Dismutase-1

(2013) Yunhua Shi et al.   JOURNAL OF MOLECULAR BIOLOGY

Deamidation of Asparagine to Aspartate Destabilizes Cu, Zn Superoxide Dismutase, Accelerates Fibrillization, and Mirrors ALS-Linked Mutations

(2013) Yunhua Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expression of zinc-deficient human superoxide dismutase in Drosophila neurons produces a locomotor defect linked to mitochondrial dysfunction

(2013) Sepehr Bahadorani et al.   NEUROBIOLOGY OF AGING

Role of histidine for charge regulation of unstructured peptides at interfaces and in bulk

(2013) Anıl Kurut et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Coupling of native IEF and extended X-ray absorption fine structure to characterize zinc-binding sites from pI isoforms of SOD1 and A4V pathogenic mutant

(2012) Sylviane Chevreux et al.   ELECTROPHORESIS

Cytotoxicity of Superoxide Dismutase 1 in Cultured Cells Is Linked to Zn2+ Chelation

(2012) Ann-Sofi Johansson et al.   PLoS One

Atomic View of a Toxic Amyloid Small Oligomer

(2012) Arthur Laganowsky et al.   SCIENCE

Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: Effect on survival

(2011) Rossella Spataro et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS

(2011) K. A. Vassall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large shifts in pKa values of lysine residues buried inside a protein

(2011) D. G. Isom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper and Zinc Metallation Status of Copper-Zinc Superoxide Dismutase from Amyotrophic Lateral Sclerosis Transgenic Mice

(2010) Herman L. Lelie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOD1 Mutations Targeting Surface Hydrogen Bonds Promote Amyotrophic Lateral Sclerosis without Reducing Apo-state Stability

(2010) Roberth Byström et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Determination of Protonation States of Histidine Residues in a 2 Å Neutron Structure of Deoxy-Human Normal Adult Hemoglobin and Implications for the Bohr Effect

(2010) Andrey Y. Kovalevsky et al.   JOURNAL OF MOLECULAR BIOLOGY

Folding Catalysis by Transient Coordination of Zn2+to the Cu Ligands of the ALS-Associated Enzyme Cu/Zn Superoxide Dismutase 1

(2010) Lina Leinartaitė et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Charges in the hydrophobic interior of proteins

(2010) D. G. Isom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structural biochemistry of the superoxide dismutases

(2009) J.J.P. Perry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Variation in aggregation propensities among ALS-associated variants of SOD1: Correlation to human disease

(2009) Mercedes Prudencio et al.   HUMAN MOLECULAR GENETICS

Metal-free Superoxide Dismutase-1 and Three Different Amyotrophic Lateral Sclerosis Variants Share a Similar Partially Unfolded β-Barrel at Physiological Temperature

(2009) Armando Durazo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis

(2008) Xiaohang Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation

(2008) Bryan F. Shaw et al.   PROTEIN SCIENCE

Protein Aggregation and Protein Instability Govern Familial Amyotrophic Lateral Sclerosis Patient Survival

(2008) Qi Wang et al.   PLOS BIOLOGY

The role of protein stability, solubility, and net charge in amyloid fibril formation

(2003) Jason P. Schmittschmitt et al.   PROTEIN SCIENCE