Small molecule screening in context: Lipid-catalyzed amyloid formation

Heme Bound Amylin: Spectroscopic Characterization, Reactivity, and Relevance to Type 2 Diabetes

(2013) Soumya Mukherjee et al.   INORGANIC CHEMISTRY

Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model

(2013) She-Qing Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Atomic structure and hierarchical assembly of a cross-  amyloid fibril

(2013) A. W. P. Fitzpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common mechanism unites membrane poration by amyloid and antimicrobial peptides

(2013) N. B. Last et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A common landscape for membrane-active peptides

(2013) Nicholas B. Last et al.   PROTEIN SCIENCE

Phosphatidylethanolamine Enhances Amyloid Fiber-Dependent Membrane Fragmentation

(2012) Michele F. M. Sciacca et al.   BIOCHEMISTRY

Analysis of the Inhibition and Remodeling of Islet Amyloid Polypeptide Amyloid Fibers by Flavanols

(2012) Ping Cao et al.   BIOCHEMISTRY

Two-Step Mechanism of Membrane Disruption by Aβ through Membrane Fragmentation and Pore Formation

(2012) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity

(2012) Marcus Fändrich   JOURNAL OF MOLECULAR BIOLOGY

A Membrane-Bound Antiparallel Dimer of Rat Islet Amyloid Polypeptide

(2011) Abhinav Nath et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide

(2011) Mazin Magzoub et al.   FASEB JOURNAL

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

(2011) Jie Xu et al.   Nature Chemical Biology

Metabolomic changes in autopsy-confirmed Alzheimer's disease

(2010) Rima Kaddurah-Daouk et al.   Alzheimers & Dementia

Hydralazine Modifies Aβ Fibril Formation and Prevents Modification by Lipidsin Vitro

(2010) Mukesh Maheshwari et al.   BIOCHEMISTRY

Are We Prepared to Deal With the Alzheimer's Disease Pandemic?

(2010) J L Holtzman   CLINICAL PHARMACOLOGY & THERAPEUTICS

Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

(2010) K. J. Potter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein-induced photophysical changes to the amyloid indicator dye thioflavin T

(2010) L. S. Wolfe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Interplay of Catalysis and Toxicity by Amyloid Intermediates on Lipid Bilayers: Insights from Type II Diabetes

(2009) James A. Hebda et al.   Annual Review of Biophysics

A Peptidomimetic Approach to Targeting Pre-amyloidogenic States in Type II Diabetes

(2009) James A. Hebda et al.   CHEMISTRY & BIOLOGY

Amyloid Precursor Protein Is a Primary Androgen Target Gene That Promotes Prostate Cancer Growth

(2008) K.-i. Takayama et al.   CANCER RESEARCH

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

(2008) M. F. M. Engel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platinum-based inhibitors of amyloid-  as therapeutic agents for Alzheimer's disease

(2008) K. J. Barnham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin

(2008) Jefferson D. Knight et al.   PROTEIN SCIENCE