High-throughput measurement, correlation analysis, and machine-learning predictions for pH and thermal stabilities of Pfizer-generated antibodies

A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative thermostability of protein mutants

(2010) Yunqi Li et al.   BMC BIOINFORMATICS

Statistical methods for assessing agreement between two methods of clinical measurement

(2010) J. Martin Bland et al.   INTERNATIONAL JOURNAL OF NURSING STUDIES

Predictor correlation impacts machine learning algorithms: implications for genomic studies

(2009) K. K. Nicodemus et al.   BIOINFORMATICS

The Design and Characterization of Oligospecific Antibodies for Simultaneous Targeting of Multiple Disease Mediators

(2009) Nazzareno Dimasi et al.   JOURNAL OF MOLECULAR BIOLOGY

High throughput thermostability screening of monoclonal antibody formulations

(2009) Feng He et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Sequence physical properties encode the global organization of protein structure space

(2009) S. Rackovsky   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of therapeutic proteins with enhanced stability

(2009) N. Chennamsetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Stabilization of α-chymotrypsin upon PEGylation correlates with reduced structural dynamics

(2008) José A. Rodríguez-Martínez et al.   BIOTECHNOLOGY AND BIOENGINEERING

A rapid, sensitive and economical assessment of monoclonal antibody conformational stability by intrinsic tryptophan fluorescence spectroscopy

(2008) Patrick Garidel et al.   Biotechnology Journal

Thermodynamically Stable Aggregation-Resistant Antibody Domains through Directed Evolution

(2008) Kristoffer Famm et al.   JOURNAL OF MOLECULAR BIOLOGY

Extrinsic Fluorescent Dyes as Tools for Protein Characterization

(2008) Andrea Hawe et al.   PHARMACEUTICAL RESEARCH

Contribution of Variable Domains to the Stability of Humanized IgG1 Monoclonal Antibodies

(2007) Roxana M. Ionescu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES