Article
Physics, Multidisciplinary
John Boone, Cynthia McCollough
Summary: Modern high-performance CT scanners excel in data acquisition speed and spatial resolution, making them unmatched among three-dimensional imaging systems.
Editorial Material
Economics
Michael Grossman
Summary: This article introduces the historical background of the author's demand for health model and its impacts on the field of health economics.
Article
Plant Sciences
Florian Moret, Gael Delorme, Gilles Clement, Claire Grosjean, Christelle Lemaitre-Guillier, Sophie Trouvelot, Marielle Adrian, Florence Fontaine
Summary: Esca is a complex grapevine trunk disease caused by wood-rotting fungi, with inconsistent foliar symptoms influenced by environmental, physiological, and genetic factors. Clonal and year-dependent metabolic responses to the disease were observed, showing different metabolite fingerprints and symptom expression between Chardonnay and Trousseau clones. Possible relationship with rainfall and higher susceptibility of certain clones were also identified.
PHYSIOLOGIA PLANTARUM
(2021)
Article
Biochemistry & Molecular Biology
Shuhui Wang Lorkowski, Jonathan D. Smith
Summary: High-density lipoprotein cholesterol (HDL-C) levels are inversely correlated with coronary heart disease (CHD), but the causal relationship between HDL and CHD is unclear. Recent studies have challenged the hypothesis that HDL is protective against CHD, but subsequent research suggests that specific HDL characteristics are causally related to decreased CHD. Different aspects of HDL structure and function may better indicate HDL's protective activity against CHD, beyond simply measuring HDL-C levels.
Article
Multidisciplinary Sciences
Gavin P. Salam, Lian-Tao Wang, Giulia Zanderighi
Summary: The discovery of the Higgs boson was a significant milestone that opened up new avenues of research. The role of the Higgs field in the Standard Model of particle physics has a profound impact on our world. Over the past ten years, insights into Higgs physics have been gained, but there are still many unanswered questions.
Article
Biochemistry & Molecular Biology
Deniz Dogan, Merve Arslan, Tugce Ulucay, Sibel Kalyoncu, Stefan Dimitrov, Seyit Kale
Summary: The study investigates the structural rearrangements of CENP-A nucleosomes resulting from antibody binding, showing that the antibodies can alter the dynamics of the nucleosomal core and indirectly affect the surrounding DNA. The binding of antibodies to the histone octamer surface is associated with conformational changes in CENP-A nucleosomes, indicating a more drastic impact compared to canonical nucleosomes. In addition, evidence suggests that the antibodies bind different octamer facades at varying affinities, revealing another level of complexity in DNA sequence regulation.
JOURNAL OF MOLECULAR BIOLOGY
(2021)
Review
Communication
Kelly Parker
Summary: This review focuses on the intersection of feminism, Hip-Hop, and education, as well as the role of Black women in shaping Hip-Hop and influencing society's perceptions. It outlines the benefits of the conference and the wide range of topics covered.
FEMINIST MEDIA STUDIES
(2023)
Article
Microbiology
Christopher A. Fenton, Qingling Tang, Daniel G. Olson, Marybeth I. Maloney, Jeffrey L. Bose, Lee R. Lynd, Aron W. Fenton
Summary: The pyruvate kinase isozyme from Thermoanaerobacterium saccharolyticum has been studied for its activation by AMP and ribose-5-phosphate, as well as its inhibition by IMP and GMP. This inhibition by IMP is specific only to a subset of bacterial PYK enzymes, indicating unique regulatory mechanisms among different isozymes.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
I. Can Kazan, Jeremy H. Mills, S. Banu Ozkan
Summary: We investigated the relationship between mutations and dynamics in Escherichia coli dihydrofolate reductase (DHFR) using computational methods. Our study used molecular dynamics simulations and developed position-specific metrics to analyze the dynamics of wild-type DHFR. We found a significant association between dynamic flexibility and mutational tolerance of DHFR positions, and identified residues that control the dynamics of specific loops. These findings can help predict functionally beneficial or detrimental substitutions and guide rational enzyme engineering.
Article
Biochemistry & Molecular Biology
Katja Leben, Ziga Strmsek, Tina Lebar, Anze Verbic, Matej Dragovan, Neza Omersa, Gregor Anderluh, Roman Jerala
Summary: DNA transcription is regulated by various mechanisms, mainly through the recruitment of RNA polymerase complex by transcription factors. In this study, we found that a TALE lacking an activation domain can enhance transcription in mammalian cells without direct interaction with multiple transcription factors. TALEs can exert their effects over a long distance and enhance the transcriptional regulation of other factors. This mechanism may involve an allosteric effect on DNA structure or dynamics.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Urban Studies
Michal Adam Kwiatkowski, Lukasz Karbowinski
Summary: This paper investigates the features that are considered most important by users of riverside cycle paths, and through a survey, it is found that being away from traffic and having a natural environment are the most important factors.
Article
Medicine, General & Internal
Akiko Inagaki, Takehiro Imura, Yasuhiro Nakamura, Kazuo Ohashi, Masafumi Goto
Summary: The study investigated a novel method of liver surface transplantation using a syngeneic keratinocyte sheet to improve the transplant efficiency for curing diabetic rats. Although this approach showed effectiveness in curing diabetic rats, the transplant efficiency did not reach that of intraportal transplantation, indicating the need for further refinements to enhance the overall effectiveness of the procedure.
JOURNAL OF CLINICAL MEDICINE
(2021)
News Item
Multidisciplinary Sciences
Dyani Lewis
Summary: Children are no more susceptible to these variants than adults, so closing schools based on incomplete information could have significant repercussions.
Article
Green & Sustainable Science & Technology
Mariapia Pazienza, Martin de Jong, Dirk Schoenmaker
Summary: Measuring Corporate Sustainability (CS) is essential for integrating sustainability into corporate practices. However, existing methodologies have limited success in real-world application. This paper examines different measurement approaches, their merits and limitations, and provides guidance for future research. The findings reveal a lack of coherence in linking mathematical measurement methods with a well-defined concept of sustainability.
Editorial Material
Multidisciplinary Sciences
Anthony King
Summary: As e-cigarettes gain popularity, the lack of knowledge about the potential harm caused by nicotine raises concerns.
Article
Chemistry, Multidisciplinary
Eva Di Silvio, Maurizio Brunori, Stefano Gianni
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2015)
News Item
Biophysics
Maurizio Brunori
BIOPHYSICAL JOURNAL
(2015)
Article
Biochemistry & Molecular Biology
Sara Chiarella, Luca Federici, Adele Di Matteo, Maurizio Brunori, Stefano Gianni
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2013)
Review
Biochemistry & Molecular Biology
Maurizio Brunori
Article
Biochemistry & Molecular Biology
Adriana Erica Miele, Andrea Bellelli, Maurizio Brunori
JOURNAL OF MOLECULAR BIOLOGY
(2013)
Article
Biochemistry & Molecular Biology
F. Angelucci, F. Saccoccia, M. Ardini, G. Boumis, M. Brunori, L. Di Leandro, R. Ippolitl, A. E. Miele, G. Natoli, S. Scotti, A. Bellelli
JOURNAL OF MOLECULAR BIOLOGY
(2013)
Review
Biochemistry & Molecular Biology
Andrea Urbani, Michele De Canio, Ferdinando Palmieri, Salvatore Sechi, Luca Bini, Massimo Castagnola, Mauro Fasano, Alessandra Modesti, Paola Roncada, Anna Maria Timperio, Luigi Bonizzi, Maurizio Brunori, Francesca Cutruzzola, Vito De Pinto, Carmine Di Ilio, Giorgio Federici, Franco Folli, Salvatore Foti, Cecilia Gelfi, Davide Lauro, Antonio Lucacchini, Fulvio Magni, Irene Messana, Pier Paolo Pandolfi, Sergio Papa, Piero Pucci, Paolo Sacchetta
MOLECULAR BIOSYSTEMS
(2013)
Article
Chemistry, Physical
Daniela Bonetti, Angelo Toto, Rajanish Giri, Angela Morrone, Domenico Sanfelice, Annalisa Pastore, Pierandrea Temussi, Stefano Gianni, Maurizio Brunori
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2014)
Article
Multidisciplinary Sciences
Rajanish Giri, Angela Morrone, Angelo Toto, Maurizio Brunori, Stefano Gianni
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2013)
Article
Multidisciplinary Sciences
Stefano Gianni, Carlo Camilloni, Rajanish Giri, Angelo Toto, Daniela Bonetti, Angela Morrone, Pietro Sormanni, Maurizio Brunori, Michele Vendruscolo
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2014)
Article
Biochemistry & Molecular Biology
Angelo Toto, Rajanish Giri, Maurizio Brunori, Stefano Gianni
Article
Biochemical Research Methods
G. Avella, C. Ardiccioni, A. Scaglione, T. Moschetti, C. Rondinelli, L. C. Montemiglio, C. Savino, A. Giuffre, M. Brunori, B. Vallone
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY
(2014)
Biographical-Item
Biochemistry & Molecular Biology
Maurizio Brunori
Review
Biochemistry & Molecular Biology
Maurizio Brunori
Summary: The process of protein folding is a spontaneous reversible process leading from an ensemble of disordered structures to the ordered functional protein. In addition to the native and denatured states, proteins can also populate a third state called amyloid, which is characteristic of incurable neurodegenerative disorders.
Article
Biology
Maurizio Brunori
Summary: This article is an extensive report on Italian science, highlighting the challenges faced by Italian scientists within the political system. It reveals the insufficient support for fundamental research in Italy. The report also mentions the ranking of four top Italian scientists and the tradition of Eraldo Antonini Lectures.
