Mining protein dynamics from sets of crystal structures using “consensus structures”

Discovery of Wild-Type and Y181C Mutant Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Using Virtual Screening with Multiple Protein Structures

(2009) Sara E. Nichols et al.   Journal of Chemical Information and Modeling

Conformational Landscape of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Non-Nucleoside Inhibitor Binding Pocket: Lessons for Inhibitor Design from a Cluster Analysis of Many Crystal Structures

(2009) Kristina A. Paris et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design of Annulated Pyrazoles as Inhibitors of HIV-1 Reverse Transcriptase∥

(2008) Zachary K. Sweeney et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

(2008) Stefan G. Sarafianos et al.   JOURNAL OF MOLECULAR BIOLOGY

High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations

(2008) K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mg2+-induced conformational switch rendering a competent DNA polymerase catalytic complex

(2007) Jesús Mendieta et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS