Nature's recipe for splitting inteins

An Atypical Naturally Split Intein Engineered for Highly Efficient Protein Labeling

(2014) Ilka V. Thiel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evolution, Mechanisms, and Applications of Intein-mediated Protein Splicing

(2014) Francine B. Perler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-based engineering and comparison of novel split inteins for protein ligation

(2014) A. Sesilja Aranko et al.   Molecular BioSystems

Recent advances in in vivo applications of intein-mediated protein splicing

(2014) Natalya I Topilina et al.   Mobile DNA

Oriented Covalent Immobilization of Antibodies for Measurement of Intermolecular Binding Forces between Zipper-Like Contact Surfaces of Split Inteins

(2013) Mirco Sorci et al.   ANALYTICAL CHEMISTRY

Structural basis for proteintrans-splicing by a bacterial intein-like domain - protein ligation without nucleophilic side chains

(2013) A. Sesilja Aranko et al.   FEBS Journal

Faster Protein Splicing with theNostoc punctiformeDnaE Intein Using Non-native Extein Residues

(2013) Manoj Cheriyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intermolecular domain swapping induces intein-mediated protein alternative splicing

(2013) A Sesilja Aranko et al.   Nature Chemical Biology

Protein Trans-Splicing of Multiple Atypical Split Inteins Engineered from Natural Inteins

(2013) Ying Lin et al.   PLoS One

Inteins: nature's gift to protein chemists

(2013) Neel H. Shah et al.   Chemical Science

Mutual synergistic protein folding in split intein

(2012) Yuchuan Zheng et al.   BIOSCIENCE REPORTS

Unprecedented Rates and Efficiencies Revealed for New Natural Split Inteins from Metagenomic Sources

(2012) Patricia Carvajal-Vallejos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultrafast Protein Splicing is Common among Cyanobacterial Split Inteins: Implications for Protein Engineering

(2012) Neel H. Shah et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Circular Permutation Prediction Reveals a Viable Backbone Disconnection for Split Proteins: An Approach in Identifying a New Functional Split Intein

(2012) Yun-Tzai Lee et al.   PLoS One

Kinetic Control of One-Pot Trans-Splicing Reactions by Using a Wild-Type and Designed Split Intein

(2011) Neel H. Shah et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evaluation and comparison of protein splicing by exogenous inteins with foreign exteins inEscherichia coli

(2011) Simo Ellilä et al.   FEBS LETTERS

Structural and Mutational Studies of a Hyperthermophilic Intein from DNA Polymerase II ofPyrococcus abyssi

(2011) Zhenming Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Highly Efficient and More Generalcis- andtrans-Splicing Inteins through Sequential Directed Evolution

(2011) Julia H. Appleby-Tagoe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conservation of intron and intein insertion sites: implications for life histories of parasitic genetic elements

(2010) Kristen S Swithers et al.   BMC EVOLUTIONARY BIOLOGY

Segmental Isotopic Labeling of a Central Domain in a Multidomain Protein by ProteinTrans-Splicing Using Only One Robust DnaE Intein

(2009) Alena E. L. Busche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Split Inteins as Versatile Tools for Protein Semisynthesis

(2009) Henning D. Mootz   CHEMBIOCHEM

Solution structure of DnaE intein fromNostoc punctiforme: Structural basis for the design of a new split intein suitable for site-specific chemical modification

(2009) Jesper S. Oeemig et al.   FEBS LETTERS

The naturally splitNpuDnaE intein exhibits an extraordinarily high rate in the proteintrans-splicing reaction

(2009) Joachim Zettler et al.   FEBS LETTERS

Novel Split Intein fortrans-Splicing Synthetic Peptide onto C Terminus of Protein

(2009) Julia H. Appleby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fractured genes: a novel genomic arrangement involving new split inteins and a new homing endonuclease family

(2009) Bareket Dassa et al.   NUCLEIC ACIDS RESEARCH

In Vivo and In Vitro Protein Ligation by Naturally Occurring and Engineered Split DnaE Inteins

(2009) A. Sesilja Aranko et al.   PLoS One

Traceless protein splicing utilizing evolved split inteins

(2009) S. W. Lockless et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Trans-Splicing as a Means for Viral Vector-Mediated In Vivo Gene Therapy

(2008) Juan Li et al.   HUMAN GENE THERAPY

Interaction Studies and Alanine Scanning Analysis of a Semi-synthetic Split Intein Reveal Thiazoline Ring Formation from an Intermediate of the Protein Splicing Reaction

(2008) Christina Ludwig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY