Central amyloid- -specific single chain variable fragment ameliorates A  aggregation and neurotoxicity

Synapse-Binding Subpopulations of Aβ Oligomers Sensitive to Peptide Assembly Blockers and scFv Antibodies

(2012) Pauline T. Velasco et al.   ACS Chemical Neuroscience

Engineered antibody approaches for Alzheimer’s disease immunotherapy

(2012) Remy Robert et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

An Effector-Reduced Anti- -Amyloid (A ) Antibody with Unique A  Binding Properties Promotes Neuroprotection and Glial Engulfment of A 

(2012) O. Adolfsson et al.   JOURNAL OF NEUROSCIENCE

Rational design of potent domain antibody inhibitors of amyloid fibril assembly

(2012) A. R. A. Ladiwala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligomerization and toxicity of Aβ fusion proteins

(2011) Joanne M. Caine et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by sortase A-mediated protein ligation

(2011) Mariusz P. Madej et al.   BIOTECHNOLOGY AND BIOENGINEERING

The Osaka FAD Mutation E22Δ Leads to the Formation of a Previously Unknown Type of Amyloid β Fibrils and Modulates Aβ Neurotoxicity

(2011) Oxana Yu. Ovchinnikova et al.   JOURNAL OF MOLECULAR BIOLOGY

Chronic Intranasal Treatment with an Anti-Aβ30-42 scFv Antibody Ameliorates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) Susann Cattepoel et al.   PLoS One

Structure-based design of conformation- and sequence-specific antibodies against amyloid  

(2011) J. M. Perchiacca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel amyloid-beta specific scFv and VH antibody fragments from human and mouse phage display antibody libraries

(2010) M. Medecigo et al.   JOURNAL OF NEUROIMMUNOLOGY

Alternative Aβ Immunotherapy Approaches for Alzheimers Disease

(2009) Terrence Town   CNS & Neurological Disorders-Drug Targets

Direct in Vivo Intracellular Selection of Conformation-sensitive Antibody Domains Targeting Alzheimer's Amyloid-β Oligomers

(2009) Giovanni Meli et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of PiB Binding to White Matter in Alzheimer Disease and Other Dementias

(2009) M. T. Fodero-Tavoletti et al.   JOURNAL OF NUCLEAR MEDICINE

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia

(2008) Takami Tomiyama et al.   ANNALS OF NEUROLOGY

The toxicity of β-amyloid is attenuated by interaction with its specific human scFv E3 in vitro

(2008) Shen Yue et al.   LIFE SCIENCES

Clearance mechanisms of Alzheimer's amyloid-β peptide: implications for therapeutic design and diagnostic tests

(2008) K A Bates et al.   MOLECULAR PSYCHIATRY

Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers

(2008) R. Robert et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Epitope mapping and neuroprotective properties of a human single chain FV antibody that binds an internal epitope of amyloid-beta 1-42

(2007) R.S. Solórzano-Vargas et al.   MOLECULAR IMMUNOLOGY

Intramuscular delivery of a single chain antibody gene reduces brain Aβ burden in a mouse model of Alzheimer's disease

(2007) Yan-Jiang Wang et al.   NEUROBIOLOGY OF AGING