Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b

Expression of hedgehog pathway components in prostate carcinoma microenvironment: shifting the balance towards autocrine signalling

(2011) Vassiliki Tzelepi et al.   HISTOPATHOLOGY

Persistent, Biologically Meaningful Prostate Cancer After 1 Year of Androgen Ablation and Docetaxel Treatment

(2011) Vassiliki Tzelepi et al.   JOURNAL OF CLINICAL ONCOLOGY

Hedgehog signaling protein expression and its association with prognostic parameters in prostate cancer: A retrospective study from the view point of new 2010 anatomic stage/prognostic groups

(2011) Tae-Jung Kim et al.   JOURNAL OF SURGICAL ONCOLOGY

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(2011) Murielle Mimeault et al.   MOLECULAR MEDICINE

The Role of Transforming Growth Factor- -Mediated Tumor-Stroma Interactions in Prostate Cancer Progression: An Integrative Approach

(2009) D. Basanta et al.   CANCER RESEARCH

Exploration of Shh and BMP paracrine signaling in a prostate cancer xenograft

(2009) Aubie Shaw et al.   DIFFERENTIATION

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

(2009) Charles M. Rudin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

(2009) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

(2009) H. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor–stroma co-evolution in prostate cancer progression and metastasis

(2009) Sajni Josson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

Comparative expression of Hedgehog ligands at different stages of prostate carcinoma progression

(2008) S Azoulay et al.   JOURNAL OF PATHOLOGY

An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer

(2008) G. Feldmann et al.   MOLECULAR CANCER THERAPEUTICS