Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo

Regulatory T cells in cancer immunotherapy

(2014) Hiroyoshi Nishikawa et al.   CURRENT OPINION IN IMMUNOLOGY

The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

(2013) Zuojia Chen et al.   IMMUNITY

Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity

(2013) Jorg van Loosdregt et al.   IMMUNITY

Development and Maintenance of Regulatory T cells

(2013) Naganari Ohkura et al.   IMMUNITY

Itch expression by Treg cells controls Th2 inflammatory responses

(2013) Hyung-seung Jin et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

Regulatory Cells and Transplantation Tolerance

(2013) S. P. Cobbold et al.   Cold Spring Harbor Perspectives in Medicine

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

An N-Terminal Mutation of the Foxp3 Transcription Factor Alleviates Arthritis but Exacerbates Diabetes

(2012) Jaime Darce et al.   IMMUNITY

STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells during Acute Murine Graft-versus-Host Disease

(2012) Arian Laurence et al.   IMMUNITY

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function

(2012) Eóin N. McNamee et al.   IMMUNOLOGIC RESEARCH

Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

(2012) Jae-Hoon Chang et al.   NATURE IMMUNOLOGY

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

(2012) E. T. Clambey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal

(2011) Kazuya Hori et al.   JOURNAL OF CELL BIOLOGY

Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1

(2011) Jorg van Loosdregt et al.   PLoS One

CD4+Foxp3+ regulatory T cell therapy in transplantation

(2011) Q. Tang et al.   Journal of Molecular Cell Biology

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

The E3 Ubiquitin Ligase GRAIL Regulates T Cell Tolerance and Regulatory T Cell Function by Mediating T Cell Receptor-CD3 Degradation

(2010) Roza I. Nurieva et al.   IMMUNITY

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

(2010) Yohsuke Harada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stability of the Regulatory T Cell Lineage in Vivo

(2010) Y. P. Rubtsov et al.   SCIENCE

Epigenetic mechanisms of regulation of Foxp3 expression

(2009) G. Lal et al.   BLOOD

Deltex1 Is a Target of the Transcription Factor NFAT that Promotes T Cell Anergy

(2009) Huey-Wen Hsiao et al.   IMMUNITY

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

(2009) James L. Riley et al.   IMMUNITY

Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?

(2009) Maria A. Curotto de Lafaille et al.   IMMUNITY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection

(2009) Guillaume Oldenhove et al.   IMMUNITY

Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion

(2009) Makoto Miyara et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

(2009) Markus Feuerer et al.   NATURE IMMUNOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4+CD44hi Cells

(2008) Jonathan A. Hill et al.   IMMUNITY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

(2008) Xuyu Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE