Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche

Osteoblastic niche supports the growth of quiescent multiple myeloma cells

(2014) Z. Chen et al.   BLOOD

Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs

(2014) Allison L. Boyd et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

(2014) L Melchor et al.   LEUKEMIA

Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation

(2014) Si Hui Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

(2014) Niccolo Bolli et al.   Nature Communications

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

(2013) Aldo M. Roccaro et al.   JOURNAL OF CLINICAL INVESTIGATION

c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer

(2013) R Nair et al.   ONCOGENE

GAS6 Receptor Status Is Associated with Dormancy and Bone Metastatic Tumor Formation

(2013) Russell S. Taichman et al.   PLoS One

Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides

(2012) J. B. Egan et al.   BLOOD

Clonal competition with alternating dominance in multiple myeloma

(2012) J. J. Keats et al.   BLOOD

Therapeutic effects of intrabone and systemic mesenchymal stem cell cytotherapy on myeloma bone disease and tumor growth

(2012) Xin Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow

(2012) Anna Mansour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor-initiating capacity of CD138− and CD138+ tumor cells in the 5T33 multiple myeloma model

(2012) E Van Valckenborgh et al.   LEUKEMIA

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

(2012) Bradley N Bidwell et al.   NATURE MEDICINE

Non-Invasive Imaging Provides Spatiotemporal Information on Disease Progression and Response to Therapy in a Murine Model of Multiple Myeloma

(2012) Simone S. Riedel et al.   PLoS One

VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors

(2011) Xin Lu et al.   CANCER CELL

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

(2011) Joji Fujisaki et al.   NATURE

Generation of a Predictive Melphalan Resistance Index by Drug Screen of B-Cell Cancer Cell Lines

(2011) Martin Boegsted et al.   PLoS One

"Microenvironmental contaminations" induced by fluorescent lipophilic dyes used for noninvasive in vitro and in vivo cell tracking

(2010) F. Lassailly et al.   BLOOD

First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial

(2010) Gareth J Morgan et al.   LANCET

Gene Expression Signatures as a Guide to Treatment Strategies for In-Transit Metastatic Melanoma

(2010) Christina K. Augustine et al.   MOLECULAR CANCER THERAPEUTICS

In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow

(2010) Cristina Lo Celso et al.   Nature Protocols

Haematopoietic stem cells depend on Gαs-mediated signalling to engraft bone marrow

(2009) Gregor B. Adams et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

The Increasing Complexity of the Cancer Stem Cell Paradigm

(2009) J. M. Rosen et al.   SCIENCE

Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance

(2008) W. Matsui et al.   CANCER RESEARCH

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY

Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma

(2008) Jesús F. San Miguel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics

(2008) P. P. Szotek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA