标题
Crystallographic structure of a small molecule SIRT1 activator-enzyme complex
作者
关键词
-
出版物
Nature Communications
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-07-02
DOI
10.1038/ncomms8645
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol
- (2013) Mahadevan Lakshminarasimhan et al. BIOSCIENCE REPORTS
- Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding
- (2013) H.-C. Hsu et al. GENES & DEVELOPMENT
- Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3
- (2013) Jeremy S. Disch et al. JOURNAL OF MEDICINAL CHEMISTRY
- The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition
- (2013) Xun Zhao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural and Functional Analysis of Human SIRT1
- (2013) Andrew M. Davenport et al. JOURNAL OF MOLECULAR BIOLOGY
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- Structural Basis for Sirtuin Activity and Inhibition
- (2012) Hua Yuan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- From Sirtuin Biology to Human Diseases: An Update
- (2012) Carlos Sebastián et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synthesis of Carba-NAD and the Structures of Its Ternary Complexes with SIRT3 and SIRT5
- (2012) Bruce G. Szczepankiewicz et al. JOURNAL OF ORGANIC CHEMISTRY
- Are sirtuins viable targets for improving healthspan and lifespan?
- (2012) Joseph A. Baur et al. NATURE REVIEWS DRUG DISCOVERY
- SIRT1 Contains N- and C-terminal Regions That Potentiate Deacetylase Activity
- (2011) Min Pan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peptide Switch Is Essential for Sirt1 Deacetylase Activity
- (2011) Hyeog Kang et al. MOLECULAR CELL
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- SIRT1 Activation by Small Molecules
- (2010) Han Dai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
- (2010) Michelle Pacholec et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
- (2010) Eric Verdin et al. TRENDS IN BIOCHEMICAL SCIENCES
- SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
- (2009) Takeshi Yoshizaki et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- A continuous microplate assay for sirtuins and nicotinamide-producing enzymes
- (2009) Brian C. Smith et al. ANALYTICAL BIOCHEMISTRY
- Structural basis for sirtuin function: What we know and what we don't
- (2009) Brandi D. Sanders et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- xia2: an expert system for macromolecular crystallography data reduction
- (2009) G. Winter JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes
- (2009) Lei Jin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of Imidazo[1,2-b]thiazole Derivatives as Novel SIRT1 Activators
- (2009) Chi B. Vu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Recent progress in the biology and physiology of sirtuins
- (2009) Toren Finkel et al. NATURE
- SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
- (2008) Alexander S. Banks et al. Cell Metabolism
- SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes
- (2008) T. Yoshizaki et al. MOLECULAR AND CELLULAR BIOLOGY
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