PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis

TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution

(2015) Ronan Broderick et al.   Nature Communications

Mitotic spindle multipolarity without centrosome amplification

(2014) Helder Maiato et al.   NATURE CELL BIOLOGY

TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability

(2013) Susanne M. Germann et al.   JOURNAL OF CELL BIOLOGY

PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA

(2013) Andreas Biebricher et al.   MOLECULAR CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

On the regulation, function, and localization of the DNA-dependent ATPase PICH

(2012) Manuel Kaulich et al.   CHROMOSOMA

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Bloom’s Syndrome and PICH Helicases Cooperate with Topoisomerase IIα in Centromere Disjunction before Anaphase

(2012) Sébastien Rouzeau et al.   PLoS One

Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase

(2011) Mei Leng et al.   CELL CYCLE

PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution

(2011) Yuwen Ke et al.   EMBO JOURNAL

All tangled up: how cells direct, manage and exploit topoisomerase function

(2011) Seychelle M. Vos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division

(2010) L. H.-C. Wang et al.   JOURNAL OF CELL SCIENCE

PICH and Cotargeted Plk1 Coordinately Maintain Prometaphase Chromosome Arm Architecture

(2010) Yasuhiro Kurasawa et al.   MOLECULAR BIOLOGY OF THE CELL

Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization

(2009) Patrick Steigemann et al.   CELL

Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs

(2009) Nadja C. Hübner et al.   CHROMOSOMA

Pericentromeric Sister Chromatid Cohesion Promotes Kinetochore Biorientation

(2009) Tessie M. Ng et al.   MOLECULAR BIOLOGY OF THE CELL

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

(2009) Kok Lung Chan et al.   NATURE CELL BIOLOGY

Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells

(2009) M. Johnson et al.   NUCLEIC ACIDS RESEARCH