Article
Biochemistry & Molecular Biology
Hanna Lesiewska, Alina Wozniak, Pawel Reisner, Krzysztof Czosnyka, Joanna Stachura, Grazyna Malukiewicz
Summary: Oxidative stress and depletion of antioxidant defenses may contribute to cataract incidence in patients under 60 years. This study measured antioxidant enzyme activity, vitamin concentrations, and oxidative stress markers in cataract patients and controls. The results showed lower activity of antioxidant enzymes and lower concentrations of vitamins A and E in cataract patients. Additionally, higher levels of lipid peroxidation and protein oxidation were observed, indicating increased oxidative stress in cataract patients. Supplementation with antioxidants could be beneficial for this group of patients.
Review
Plant Sciences
Anna Ekner-Grzyb, Anna Duka, Tomasz Grzyb, Isabel Lopes, Jagna Chmielowska-Bak
Summary: Pollution of the environment with plastic is a significant concern in the modern world. Despite recycling methods, a substantial amount of plastic is still deposited in the environment. Nanoplastic, in particular, poses a serious danger as it can be effectively taken up and transported within organisms. It has been found to exert toxic effects on plants, mainly through oxidative response.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Environmental Sciences
Megha Murali, T. Shivanandappa
Summary: Endosulfan exposure causes high levels of oxidative stress in the liver and brain, leading to reduced antioxidant enzyme activity and increased ROS and lipid peroxidation. The brain is more susceptible to oxidative stress than the liver, likely due to its lower antioxidant defenses and higher oxygen consumption.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Plant Sciences
Kristina Petrovic, Jovana Sucur Elez, Marina Crnkovic, Slobodan Krsmanovic, Milos Rajkovic, Boris Kuzmanovic, Dorde Malencic
Summary: Oxidative stress in soybean plants infected with Diaporthe isolates was evaluated to select the least aggressive inoculation method, determine the most aggressive Diaporthe isolate, and identify the most tolerant soybean cultivar.
Article
Physiology
Yi Zhang, Jialong Wu, Lai Jiang, Chenkang Lu, Zhengwei Huang, Bin Liu
Summary: Fluorine induces oxidative stress leading to cellular damage; depletion of GSH and increased oxidized GSH in high fluoride environments; fluoride-induced oxidative stress and ferroptosis are related due to iron metabolism disorders.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Da-Young Lee, Moon-Young Song, Eun-Hee Kim
Summary: Colorectal cancer has a high prevalence in patients with inflammatory bowel disease, and oxidative stress is known to be one of the causes of inflammatory diseases and malignant disorders. The Nrf2/KEAP1 pathway is believed to protect cells from oxidative stress and inflammation. Phytochemicals may play a role in preventing or inhibiting colorectal cancer progression.
Article
Biochemistry & Molecular Biology
Azza A. A. Attia, Jehan M. M. Sorour, Neama A. A. Mohamed, Tagreed T. T. Mansour, Rasha A. A. Al-Eisa, Nahla S. S. El-Shenawy
Summary: This study aimed to investigate the protective role of vitamin E in improving cardiotoxicity induced by cyclophosphamide in rats. The results showed that vitamin E could attenuate the elevation of cardiac markers, increase in lipid profiles, reduction in antioxidant enzyme activities, and increase in lipid peroxidation. In addition, vitamin E was found to improve the histopathological alterations caused by cyclophosphamide.
Article
Biochemistry & Molecular Biology
Roland Wesolowski, Celestyna Mila-Kierzenkowska, Marta Pawlowska, Karolina Szewczyk-Golec, Lukasz Saletnik, Pawel Sutkowy, Alina Wozniak
Summary: Cold-water exposure leads to the up-regulation of antioxidant defenses and reduces oxidative distress. Winter swimmers show increased antioxidant capacity and reduced oxidative stress due to regular cold exposure.
Article
Environmental Sciences
Chahrazad Belaid, Ibtissem Sbartai
Summary: Thiram is able to induce oxidative damage in the aquatic organism Daphnia magna, depleting antioxidants, increasing lipid peroxidation, and leading to oxidative stress and ultimately death. The study highlights the importance of assessing the effects of Thiram on non-vertebrate organisms.
Article
Microbiology
Mishka Ismail, Vartika Srivastava, Musa Marimani, Aijaz Ahmad
Summary: Outbreaks associated with Candida auris have increased globally. This study assessed the impact of carvacrol on the growth and survival of C. auris, as well as its effect on antioxidant enzymes and lipid peroxidation. The results showed that carvacrol has antifungal activity and induces oxidative stress.
RESEARCH IN MICROBIOLOGY
(2022)
Article
Plant Sciences
Biswajit Bose, Suman Kumaria, Pramod Tandon
Summary: The study found that Jatamansi grows better in conditions of low temperature and higher light intensity, achieving higher regeneration rates and shoot numbers. Through in vitro propagation, genetic fidelity of the species was maintained, and increased antioxidant enzyme activities were observed under oxidative stress conditions.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Plant Sciences
Ke Dang, Xiangwei Gong, Haofeng Liang, Shuqing Guo, Suiqi Zhang, Baili Feng
Summary: Shading can restrict photosynthesis and plant growth. Understanding the effects of phosphorus application on mung beans under shading stress is important for efficient planting structures and optimizing P-use management.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Pharmacology & Pharmacy
Anita Yovas, W. A. Manjusha, Stanely Mainzen Prince Ponnian
Summary: β-Caryophyllene has antioxidant effects and can protect the heart by inhibiting the intrinsic pathway of cardiomyocyte apoptosis and reducing infarct size.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2022)
Article
Veterinary Sciences
Vladimira Erjavec, Tomaz Vovk, Alenka Nemec Svete
Summary: This study assessed the health status of trained canicross dogs participating in two acute bouts of exercise with their owners during the training season. The results showed that these dogs were healthy, in good physical condition, and fit for the exercise.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Agnieszka Partyka, Wojciech Nizanski
Summary: The balance between ROS formation and the antioxidant system is crucial for cell function. Supplementation with antioxidants and other compounds shows potential for improving avian semen quality and fertility.
Letter
Pharmacology & Pharmacy
Maha Chhoumi, Amel Mrad, Anwar Mechri
Article
Immunology
Achraf Jemli, Awatef Eshili, Fatma Trifa, Anouar Mechri, Ferid Zaafrane, Lotfi Gaha, George Juckel, Besma Bel Hadj Jrad Tensaout
IMMUNOLOGICAL INVESTIGATIONS
(2017)
Article
Psychiatry
Achraf Jemli, Oumaima Inoubli, Fatma Trifa, Anouar Mechri, Ferid Zaafrane, Lotfi Gaha, Besma Bel Hadj Jrad
NORDIC JOURNAL OF PSYCHIATRY
(2017)
Article
Psychiatry
Amel Mrad, Mohamed Wassim Krir, Ines Ajmi, Lotfi Gaha, Anwar Mechri
PSYCHIATRY RESEARCH
(2016)
Article
Psychiatry
Awatef Esshili, Sihem Thabet, Achraf Jemli, Fatma Trifa, Anouar Mechri, Ferid Zaafrane, Lotfi Gaha, Georg Juckel, Hamouda Babba, Besma Bel Hadj Jrad
PSYCHIATRY RESEARCH
(2016)
Article
Psychology, Clinical
E. Fonseca-Pedrero, M. Debbane, J. Ortuno-Sierra, R. C. K. Chan, D. C. Cicero, L. C. Zhang, C. Brenner, E. Barkus, R. J. Linscott, T. Kwapil, N. Barrantes-Vidal, A. Cohen, A. Raine, M. T. Compton, E. B. Tone, J. Suhr, J. Muniz, A. Fumero, S. Giakoumaki, I. Tsaousis, A. Preti, M. Chmielewski, J. Laloyaux, A. Mechri, M. A. Lahmar, V. Wuthrich, F. Laroi, J. C. Badcock, A. Jablensky
PSYCHOLOGICAL MEDICINE
(2018)
Article
Psychiatry
Ahmed Mhalla, Bochra Ben Mohamed, Christoph U. Correll, Badii Amamou, Anouar Mechri, Lotfi Gaha
ANNALS OF GENERAL PSYCHIATRY
(2017)
Article
Neurosciences
A. Mhalla, N. Boussaid, L. Gassab, L. Gaha, A. Mechri
ENCEPHALE-REVUE DE PSYCHIATRIE CLINIQUE BIOLOGIQUE ET THERAPEUTIQUE
(2013)
Article
Medical Laboratory Technology
H. Mabrouk, I. Houas, H. Mechria, A. Mechri, W. Douki, L. Gaha, M. F. Najjar
IMMUNO-ANALYSE & BIOLOGIE SPECIALISEE
(2013)
Article
Psychiatry
Eduardo Fonseca-Pedrero, Javier Ortuno-Sierra, Beatriz Lucas-Molina, Martin Debbane, Raymond C. K. Chan, David C. Cicero, Lisa C. Zhang, Colleen Brenner, Emma Barkus, Richard J. Linscott, Thomas Kwapil, Neus Barrantes-Vidal, Alex Cohen, Adrian Raine, Michael T. Compton, Erin B. Tone, Julie Suhr, Julio Bobes, Axit Fumero, Stella Giakoumaki, Ioannis Tsaousis, Antonio Preti, Michael Chmielewski, Julien Laloyaux, Anwar Mechri, Mohamed Aymen Lahmar, Viviana Wuthrich, Frank Laroi, Johanna C. Badcock, Assen Jablensky, David Barron, Viren Swami, Ulrich S. Tran, Martin Voracek
SCHIZOPHRENIA RESEARCH
(2018)
Article
Psychology, Multidisciplinary
Mehmet Eskin, Omar Kujan, Martin Voracek, Amira Shaheen, Mauro Giovanni Carta, Jian-Min Sun, Chris Flood, Senel Poyrazli, Mohsen Janghorbani, Kouichi Yoshimasu, Anwar Mechri, Yousef Khader, Khouala Aidoudi, Seifollah Bakhshi, Hacer Harlak, Muna Ahmead, Maria Francesca Moro, Hani Nawafleh, Louise Phillips, Abdulwahab Abuderman, Ulrich S. Tran, Kanami Tsuno
SCANDINAVIAN JOURNAL OF PSYCHOLOGY
(2016)
Article
Genetics & Heredity
Monia Raffa, Besma Bel Hadj Jrad, Amel Haj Khelil, Abdelhamid Kerkeni, Anwar Mechri
Article
Public, Environmental & Occupational Health
I. Anes Jellali, M. A. Jellali, R. Gataa, A. Mechri
Article
Psychiatry
Hajer Mabrouk, Haithem Mechria, Anouar Mechri, Islam Azizi, Fadoua Neffati, Wahiba Douki, Lotfi Gaha, Mohamed Fadhel Najjar
ASIAN JOURNAL OF PSYCHIATRY
(2014)
Article
Psychiatry
Mehmet Eskin, Jian-Min Sun, Jamila Abuidhail, Kouichi Yoshimasu, Omar Kujan, Mohsen Janghorbani, Chris Flood, Mauro Giovanni Carta, Ulrich S. Tran, Anwar Mechri, Motasem Hamdan, Senel Poyrazli, Khouala Aidoudi, Seifollah Bakhshi, Hacer Harlak, Maria Francesca Moro, Hani Nawafleh, Louise Phillips, Amira Shaheen, Shahama Taifour, Kanami Tsuno, Martin Voracek
ARCHIVES OF SUICIDE RESEARCH
(2016)
Article
Clinical Neurology
Nadia Deflorin, Ulrike Ehlert, Rita T. Amiel Castro
Summary: Changes in the gut microbiome of infants have been associated with maternal psychological symptoms during pregnancy. This study found that maternal prenatal depressive symptoms are associated with lower diversity of the infant's microbiome, while maternal saliva cortisol levels are linked to increased diversity and changes in specific bacterial groups. Further research is needed to understand the implications of these microbiota alterations for child health.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Zheng Ma, Hui-Xia Zhou, Da-Chun Chen, Dong-Mei Wang, Xiang-Yang Zhang
Summary: The impaired glucose metabolism in drug-na & iuml;ve schizophrenia patients is strongly associated with suicidal behavior, suggesting that glucose metabolism abnormalities may be potential biomarkers of suicide in schizophrenia patients. Regular monitoring of glucose metabolism variables is essential for suicide prevention.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Katie M. Lavigne, Jiaxuan Deng, Delphine Raucher-Chene, Adele Hotte-Meunier, Chloe Voyer, Lisa Sarraf, Martin Lepage, Genevieve Sauve
Summary: Psychiatric disorders are characterized by cognitive deficits and cognitive biases, which are associated with specific symptoms. While cognitive biases are present across diagnoses, their severity varies.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Yong-Yu Yin, Jiao-Zhao Yan, Shi-Xin Lai, Qian-Qian Wei, Si-Rui Sun, Li-Ming Zhang, Yun-Feng Li
Summary: This study found that gamma oscillations are closely associated with depression and may serve as predictive biomarkers of depression. Chronic restraint stress and lipopolysaccharide induced significant depression-like behaviors in mice and reduced gamma oscillations in the medial prefrontal cortex. Administration of ketamine, scopolamine, or fluoxetine increased gamma oscillations and exhibited rapid-acting antidepressant effects.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Veronica Begni, Moira Marizzoni, Kerstin Camile Creutzberg, Diana Morena Silipo, Mariusz Papp, Annamaria Cattaneo, Marco Andrea Riva
Summary: Exposure to stressful experiences is a significant risk factor for mental disorders, and pharmacological interventions targeting stress-induced alterations can help restore brain function. Lurasidone, an antipsychotic drug, has been shown to normalize the impairments caused by stress exposure and could be a valuable treatment for stress-induced mental illnesses. However, the mechanisms underlying the therapeutic effects of lurasidone are not well understood. This study found that chronic lurasidone treatment counteracted some of the transcriptional changes induced by chronic mild stress exposure, providing new insights into the potential therapeutic effects of lurasidone.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Esther E. Palacios-Barrios, Kunal Patel, Jamie L. Hanson
Summary: This review examines the association between early life interpersonal stress (ELIS) and depression, as well as the underlying mechanisms. The research shows that ELIS affects how youth respond to social rewards, and similar impairments in social reward processing are observed in youth with depression. The authors propose a preliminary model that suggests neurobehavioral disruptions in social reward processing as a mediating factor in the connection between ELIS and depression.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Rui Li, Jiaming Tang, Yizhuo Wang, Ying Wang, Hua Yang, Hongen Wei
Summary: Restricted and repetitive behaviors (RRBs) are characteristic features of neuropsychiatric disorders. This study focused on repetitive self-grooming behavior and investigated the involvement of the Pax2 gene in its control. Through the use of Pax2 neuron-specific deletion mice, the study found that the deletion of Pax2 gene affects the expression of the Arc gene in the prefrontal cortex, leading to impaired synaptic plasticity and excitatory/inhibitory imbalance, thereby contributing to the occurrence of repetitive self-grooming behavior.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Sara Derosa, Paulina Misztak, Jessica Mingardi, Giulia Mazzini, Heidi Kaastrup Muller, Laura Musazzi
Summary: This study investigated the involvement of neurotrophic signaling pathways in stress vulnerability/resilience and fast antidepressant response/non-response to ketamine in a rat model of depression. The findings showed that stress and ketamine induced specific changes in these pathways in different brain areas and subcellular fractions.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Review
Clinical Neurology
Georgia F. Caruana, Sean P. Carruthers, Michael Berk, Susan L. Rossell, Tamsyn E. Van Rheenen
Summary: Cognitive impairment is related to both white matter macrostructure and microstructure in bipolar disorder patients. However, there is inconsistency in the results of the studies examining this relationship. Some studies have found an association between higher fractional anisotropy in white matter and better complex attention skills and executive functioning in bipolar disorder patients, while others have found no associations. Further research with increased statistical power and standardized methods is needed.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Review
Clinical Neurology
Alberto Galimberti, Martin Tik, Giovanni Pellegrino, Anna-Lisa Schuler
Summary: This study provides a systematic review and meta-analysis on the effectiveness of repetitive transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) for post-traumatic brain injury (TBI) symptoms. The results show that non-invasive brain stimulation techniques have a small overall effect on TBI sequelae, with significant effects observed for anxiety and headache. However, larger randomized controlled trials with longer follow-ups, optimized stimulation parameters, and standardized methodology are needed to establish the efficacy of these techniques in addressing TBI sequelae.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Amanda J. Sales, Pedro H. Gobira, Joa F. C. Pedrazzi, Joao R. Silveia, Elaine Del Bel, Felipe V. Gomes, Francisco S. Guimaraes
Summary: The study found that doxycycline can inhibit metalloproteinase in the brain and attenuate the rewarding effects and locomotor sensitization of drug abuse. This suggests that doxycycline could be repurposed for the treatment of substance use disorders.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Alejandro Borrego-Ruiz, Juan J. Borrego
Summary: There is substantial evidence that the development of the nervous system is related to the composition and functions of the gut microbiome. The communication between the central nervous system (CNS) and the gut microbiota is bidirectional, with various routes such as immune, endocrine, and neural circuits. Dysbiosis of the gut microbiota has been associated with neuropsychiatric diseases and psychological disorders. Fecal microbiota transplantation (FMT) therapy has shown a causal-effect relationship between the gut microbiota and behavioral features. Interventions based on prebiotics, probiotics, or synbiotics have demonstrated their influence on neurological disorders through the synthesis of neuroactive compounds and regulation of inflammatory and endocrine processes. Further research is needed to explore the impact of gut microbiota dysbiosis on psychiatric and psychological disorders and the potential therapeutic role of microbiota-based interventions.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Zhinan Li, Zhuang Kang, Xiaowei Xia, Leijun Li, Junyan Wu, Jiamin Dai, Tong Liu, Cai Chen, Yong Qiu, Ming Chen, Yanxi Liu, Ziyi Zhang, Zili Han, Zhengjia Dai, Qinling Wei
Summary: This study found that patients with schizophrenia showed lower levels of resilience and cognitive functions compared to healthy controls, as well as abnormal global properties and nodal metrics in brain networks. Furthermore, characteristic path length might moderate the relationship between resilience and working memory in these patients.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
David H. Adamowicz, Tsung-Chin Wu, Rebecca Daly, Michael R. Irwin, Dilip Jeste, Xin M. Tu, Lisa T. Eyler, Ellen E. Lee
Summary: This study aimed to explore the relationship between executive functioning and inflammatory biomarkers in people with schizophrenia. The results showed that systemic inflammation did not predict long-term declines in executive functioning. This suggests the need for further research to better understand the relationship and mechanisms between inflammation and cognition in schizophrenia.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)
Article
Clinical Neurology
Nina Walter, Julian Wenzel, Shalaila S. Haas, Letizia Squarcina, Carolina Bonivento, Anne Ruef, Dominic Dwyer, Theresa Lichtenstein, Oeznur Bastruek, Alexandra Stainton, Linda A. Antonucci, Paolo Brambilla, Stephen J. Wood, Rachel Upthegrove, Stefan Borgwardt, Rebekka Lencer, Eva Meisenzahl, Raimo K. R. Salokangas, Christos Pantelis, Alessandro Bertolino, Nikolaos Koutsouleris, Joseph Kambeitz, Lana Kambeitz-Ilankovic
Summary: Clinical and neuroimaging data can be used to predict the potential of cognitive training to improve social functioning in recent onset psychosis patients. The use of multivariate pattern analysis and support vector machine classifier allows for the prediction of social functioning improvement based on baseline cognitive data. The findings suggest that cognitive data can provide a robust individual estimate of future social functioning for patients with recent onset psychosis.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2024)