MtDNA mutagenesis impairs elimination of mitochondria during erythroid maturation leading to enhanced erythrocyte destruction

In vivolevels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice

(2014) Angela Logan et al.   AGING CELL

Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice

(2014) XiuJie Li-Harms et al.   BLOOD

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice

(2014) Jill E. Kolesar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes

(2014) Shinya Honda et al.   Nature Communications

Oxidative Stress and Suicidal Erythrocyte Death

(2013) Florian Lang et al.   ANTIOXIDANTS & REDOX SIGNALING

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

Iron Metabolism: Interactions with Normal and Disordered Erythropoiesis

(2013) T. Ganz et al.   Cold Spring Harbor Perspectives in Medicine

N-acetylcysteine reduces oxidative stress in sickle cell patients

(2012) Erfan Nur et al.   ANNALS OF HEMATOLOGY

The impact of erythrocyte age on eryptosis

(2012) Mehrdad Ghashghaeinia et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice

(2012) Kati J. Ahlqvist et al.   Cell Metabolism

Anaemia in the elderly: An aetiologic profile of a prospective cohort of 95 hospitalised patients

(2012) Inessa Petrosyan et al.   European Journal of Internal Medicine

Anemia in elderly patients: New insight into an old disorder

(2012) Emmanuel Andrès et al.   Geriatrics & Gerontology International

Coming into View: Eukaryotic Iron Chaperones and Intracellular Iron Delivery: FIGURE 1.

(2012) Caroline C. Philpott   JOURNAL OF BIOLOGICAL CHEMISTRY

A Double in vivo Biotinylation Technique for Objective Assessment of Aging and Clearance of Mouse Erythrocytes in Blood Circulation

(2012) Rajiv K. Saxena et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

A ROS rheostat for cell fate regulation

(2012) Maria Maryanovich et al.   TRENDS IN CELL BIOLOGY

Mechanisms of mitochondrial diseases

(2011) Emil Ylikallio et al.   ANNALS OF MEDICINE

Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

(2011) Toshio Suda et al.   Cell Stem Cell

Regulation of Phosphatidylserine Exposure in Red Blood Cells

(2011) Duc Bach Nguyen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Redox control of iron regulatory protein 2 stability

(2011) Anja Hausmann et al.   FEBS LETTERS

Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy

(2011) Joung Hyuck Joo et al.   MOLECULAR CELL

Reticulocyte mitophagy: Monitoring mitochondrial clearance in a mammalian model

(2010) Ji Zhang et al.   Autophagy

Empowering self-renewal and differentiation: the role of mitochondria in stem cells

(2010) Jalees Rehman   JOURNAL OF MOLECULAR MEDICINE-JMM

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Autophagy-dependent and -independent mechanisms of mitochondrial clearance during reticulocyte maturation

(2009) Ji Zhang et al.   Autophagy

Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction

(2009) M. L. Chen et al.   BLOOD

Mouse models of mitochondrial DNA defects and their relevance for human disease

(2009) Henna Tyynismaa et al.   EMBO REPORTS

Systemic oxidative stress in classic Rett syndrome

(2009) Claudio De Felice et al.   FREE RADICAL BIOLOGY AND MEDICINE

Free iron, total F2-isoprostanes and total F4-neuroprostanes in a model of neonatal hypoxic-ischemic encephalopathy: neuroprotective effect of melatonin

(2009) Cinzia Signorini et al.   JOURNAL OF PINEAL RESEARCH

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

(2008) M. Kundu et al.   BLOOD

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE