Deoxynybomycins inhibit mutant DNA gyrase and rescue mice infected with fluoroquinolone-resistant bacteria

Dual Small-Molecule Targeting of Procaspase-3 Dramatically Enhances Zymogen Activation and Anticancer Activity

(2014) Rachel C. Botham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success

(2014) Liam S. Redgrave et al.   TRENDS IN MICROBIOLOGY

Efficient NQO1 Substrates are Potent and Selective Anticancer Agents

(2013) Elizabeth I. Parkinson et al.   ACS Chemical Biology

Overcoming Target-Mediated Quinolone Resistance in Topoisomerase IV by Introducing Metal-Ion-Independent Drug–Enzyme Interactions

(2013) Katie J. Aldred et al.   ACS Chemical Biology

New Mechanistic and Functional Insights into DNA Topoisomerases

(2013) Stefanie Hartman Chen et al.   Annual Review of Biochemistry

High abundance and diversity of antimicrobial resistance determinants among early vancomycin-resistant Enterococcus faecium in Poland

(2013) E. Sadowy et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Polymorphic mutation frequencies in clinical isolates ofStaphylococcus aureus: the role of weak mutators in the development of fluoroquinolone resistance

(2013) Shaochen Wang et al.   FEMS MICROBIOLOGY LETTERS

Association of norB overexpression and fluoroquinolone resistance in clinical isolates of Staphylococcus aureus from Korea

(2013) Y. G. Kwak et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Phenotypic and genotypic evaluation of fluoroquinolone resistance in clinical isolates of Staphylococcus aureus in Tehran

(2013) Marzieh Aligholi et al.   MEDICAL SCIENCE MONITOR

U.S. Outpatient Antibiotic Prescribing, 2010

(2013) Lauri A. Hicks et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of hospital-associated lineages of ampicillin-resistant Enterococcus faecium from clinical cases in dogs and humans

(2013) Cindy-Love Tremblay et al.   Frontiers in Microbiology

Drugging Topoisomerases: Lessons and Challenges

(2012) Yves Pommier   ACS Chemical Biology

Inside Cover: Identification of a Novel Protein Synthesis Inhibitor Active against Gram-Positive Bacteria (ChemBioChem 4/2012)

(2012) Nora R. Eibergen et al.   CHEMBIOCHEM

Resistance surveillance studies: a multifaceted problem—the fluoroquinolone example

(2012) A. Dalhoff   INFECTION

Curing bacteria of antibiotic resistance: reverse antibiotics, a novel class of antibiotics in nature

(2012) Keiichi Hiramatsu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Selection of operating parameters on the basis of hydrodynamics in centrifugal partition chromatography for the purification of nybomycin derivatives

(2012) S. Adelmann et al.   JOURNAL OF CHROMATOGRAPHY A

Antibiotic resistance and virulence traits in clinical and environmental Enterococcus faecalis and Enterococcus faecium isolates

(2012) I.U. Rathnayake et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY

Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

(2011) Sofia Costa et al.   BMC MICROBIOLOGY

Topoisomerase Mutations That Are Associated with High-Level Resistance to Earlier Fluoroquinolones in Staphylococcus aureus Have Less Effect on the Antibacterial Activity of Besifloxacin

(2011) Christine M. Sanfilippo et al.   CHEMOTHERAPY

Prevalence and Mechanism of Antimicrobial Resistance in Staphylococcus aureus Isolates from Diseased Cattle, Swine and Chickens in Japan

(2011) Kotaro BABA et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Pseudonocardians A–C, New Diazaanthraquinone Derivatives from a Deap-Sea Actinomycete Pseudonocardia sp. SCSIO 01299

(2011) Sumei Li et al.   Marine Drugs

Extended Spectrum of Quinolone Resistance, Even to a Potential Latter Third-Generation Agent, as a Result of a Minimum of Two GrlA and Two GyrA Alterations in Quinolone-Resistant Staphylococcus aureus

(2010) Eun-Jeong Yoon et al.   CHEMOTHERAPY

Chemistry and Biology of Deoxynyboquinone, a Potent Inducer of Cancer Cell Death

(2010) Joseph S. Bair et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Type IIA topoisomerase inhibition by a new class of antibacterial agents

(2010) Benjamin D. Bax et al.   NATURE

Quinolone Resistance in Neisseria gonorrhoeae: Rapid Genotyping of Quinolone Resistance-Determining Regions in gyrA and parC Genes by Melting Curve Analysis Predicts Susceptibility

(2009) F. Vernel-Pauillac et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-level ciprofloxacin resistance among hospital-adapted Enterococcus faecium (CC17)

(2009) Guido Werner et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Correlation of Antimicrobial Resistance with  -Lactamases, the OmpA-Like Porin, and Efflux Pumps in Clinical Isolates of Acinetobacter baumannii Endemic to New York City

(2008) S. Bratu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY