Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

(2015) Andrea Ditadi et al.   NATURE CELL BIOLOGY

Notch1 Is Pan-Endothelial at the Onset of Flow and Regulated by Flow

(2015) Espen D. Jahnsen et al.   PLoS One

Progressive maturation toward hematopoietic stem cells in the mouse embryo aorta

(2014) J.-C. Boisset et al.   BLOOD

Discrete Notch signaling requirements in the specification of hematopoietic stem cells

(2014) A. D. Kim et al.   EMBO JOURNAL

Sox17-Mediated Maintenance of Fetal Intra-Aortic Hematopoietic Cell Clusters

(2014) I. Nobuhisa et al.   MOLECULAR AND CELLULAR BIOLOGY

Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs

(2013) S. Gordon-Keylock et al.   BLOOD

Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells

(2013) J. Tober et al.   DEVELOPMENT

Endothelio-Mesenchymal Interaction Controls runx1 Expression and Modulates the notch Pathway to Initiate Aortic Hematopoiesis

(2013) Charlotte Richard et al.   DEVELOPMENTAL CELL

Hemogenic Endothelial Cell Specification Requires c-Kit, Notch Signaling, and p27-Mediated Cell-Cycle Control

(2013) Kathrina L. Marcelo et al.   DEVELOPMENTAL CELL

The expression of Sox17 identifies and regulates haemogenic endothelium

(2013) Raedun L. Clarke et al.   NATURE CELL BIOLOGY

Sox17 is indispensable for acquisition and maintenance of arterial identity

(2013) Monica Corada et al.   Nature Communications

Haemogenic endocardium contributes to transient definitive haematopoiesis

(2013) Haruko Nakano et al.   Nature Communications

Integrin  IIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta

(2013) J.-C. Boisset et al.   Biology Open

Role of SOX17 in hematopoietic development from human embryonic stem cells

(2012) Y. Nakajima-Takagi et al.   BLOOD

Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development

(2012) Zhuan Li et al.   Cell Stem Cell

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

(2012) Monika Lichtinger et al.   EMBO JOURNAL

CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells

(2011) C. Robin et al.   BLOOD

Erythroid/Myeloid Progenitors and Hematopoietic Stem Cells Originate from Distinct Populations of Endothelial Cells

(2011) Michael J. Chen et al.   Cell Stem Cell

Stepwise arteriovenous fate acquisition during mammalian vasculogenesis

(2011) Diana C. Chong et al.   DEVELOPMENTAL DYNAMICS

Sox17 modulates Wnt3A/β-catenin-mediated transcriptional activation of the Lef-1 promoter

(2010) Xiaoming Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis

(2010) N. Sasaki et al.   DEVELOPMENT

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos

(2010) T. Yokomizo et al.   DEVELOPMENT

β1 Integrin Establishes Endothelial Cell Polarity and Arteriolar Lumen Formation via a Par3-Dependent Mechanism

(2010) Ann C. Zovein et al.   DEVELOPMENTAL CELL

Hematopoietic stem cell activity in the aorta-gonad-mesonephros region enhances after mid-day 11 of mouse development

(2010) Erin Taylor et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence

(2009) C. E. Burns et al.   BLOOD

Pax3:Foxc2 Reciprocal Repression in the Somite Modulates Muscular versus Vascular Cell Fate Choice in Multipotent Progenitors

(2009) Mounia Lagha et al.   DEVELOPMENTAL CELL

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Continuous single-cell imaging of blood generation from haemogenic endothelium

(2009) Hanna M. Eilken et al.   NATURE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

The Emergence of Hematopoietic Stem Cells Is Initiated in the Placental Vasculature in the Absence of Circulation

(2008) Katrin E. Rhodes et al.   Cell Stem Cell

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1

(2008) Àlex Robert-Moreno et al.   EMBO JOURNAL

Fluid shear stress induces arterial differentiation of endothelial progenitor cells

(2008) Syotaro Obi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mind bomb-1 Is Essential for Intraembryonic Hematopoiesis in the Aortic Endothelium and the Subaortic Patches

(2008) M.-J. Yoon et al.   MOLECULAR AND CELLULAR BIOLOGY

All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac

(2007) C. T. Lux et al.   BLOOD