ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning

Imaging techniques for visualizing and phenotyping congenital heart defects in murine models

(2013) Xiaoqin Liu et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Interrogating Congenital Heart Defects With Noninvasive Fetal Echocardiography in a Mouse Forward Genetic Screen

(2013) Xiaoqin Liu et al.   Circulation-Cardiovascular Imaging

NEK8 Links the ATR-Regulated Replication Stress Response and S Phase CDK Activity to Renal Ciliopathies

(2013) Hyo Jei Claudia Choi et al.   MOLECULAR CELL

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3

(2013) Sylvia Hoff et al.   NATURE GENETICS

A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8

(2012) John K McCooke et al.   BMC GENOMICS

Loss of the Ciliary Kinase Nek8 Causes Left-Right Asymmetry Defects

(2012) D. K. Manning et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd2

(2012) S. Yoshiba et al.   SCIENCE

The ciliary transition zone: from morphology and molecules to medicine

(2012) Peter G. Czarnecki et al.   TRENDS IN CELL BIOLOGY

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

(2011) Liyun Sang et al.   CELL

Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2

(2011) S. Field et al.   DEVELOPMENT

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

(2011) Corey L. Williams et al.   JOURNAL OF CELL BIOLOGY

A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

(2011) Francesc R Garcia-Gonzalo et al.   NATURE GENETICS

The polycystic kidney disease-related proteins Bicc1 and SamCystin interact

(2009) Emily E. Stagner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of Nephrocystin-3 Function Can Cause Embryonic Lethality, Meckel-Gruber-like Syndrome, Situs Inversus, and Renal-Hepatic-Pancreatic Dysplasia

(2008) Carsten Bergmann et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nek8 Regulates the Expression and Localization of Polycystin-1 and Polycystin-2

(2008) E. Sohara et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NEK8 Mutations Affect Ciliary and Centrosomal Localization and May Cause Nephronophthisis

(2008) E. A. Otto et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY