标题
Abasic pivot substitution harnesses target specificity of RNA interference
作者
关键词
-
出版物
Nature Communications
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-12-18
DOI
10.1038/ncomms10154
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Transcriptome-wide Discovery of microRNA Binding Sites in Human Brain
- (2014) Ryan L. Boudreau et al. NEURON
- Structural basis for microRNA targeting
- (2014) N. T. Schirle et al. SCIENCE
- miRTCat: a comprehensive map of human and mouse microRNA target sites including non-canonical nucleation bulges
- (2013) Ka-Kyung Kim et al. BIOINFORMATICS
- Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
- (2013) Aleksandra Helwak et al. CELL
- MicroRNAs: regulators of neuronal fate
- (2013) Alfred X Sun et al. CURRENT OPINION IN CELL BIOLOGY
- RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression
- (2013) J. Liu et al. NUCLEIC ACIDS RESEARCH
- The Structure of Human Argonaute-2 in Complex with miR-20a
- (2012) Elad Elkayam et al. CELL
- A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens
- (2012) Frederic D Sigoillot et al. NATURE METHODS
- Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
- (2012) Cole Trapnell et al. Nature Protocols
- A 'pivotal' new rule for microRNA-mRNA interactions
- (2012) Giovanni Stefani et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- An alternative mode of microRNA target recognition
- (2012) Sung Wook Chi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Crystal Structure of Human Argonaute2
- (2012) N. T. Schirle et al. SCIENCE
- Modified siRNA Structure With a Single Nucleotide Bulge Overcomes Conventional siRNA-mediated Off-target Silencing
- (2011) Pooja Dua et al. MOLECULAR THERAPY
- Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
- (2010) Markus Hafner et al. CELL
- A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects
- (2010) Jesper B. Bramsen et al. NUCLEIC ACIDS RESEARCH
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- The promises and pitfalls of RNA-interference-based therapeutics
- (2009) Daniela Castanotto et al. NATURE
- Digital transcriptome profiling using selective hexamer priming for cDNA synthesis
- (2009) Christopher D Armour et al. NATURE METHODS
- Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
- (2009) Aimee L. Jackson et al. NATURE REVIEWS DRUG DISCOVERY
- MicroRNA-like off-target transcript regulation by siRNAs is species specific
- (2009) J. Burchard et al. RNA
- MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation
- (2008) Jenn-Yah Yu et al. EXPERIMENTAL CELL RESEARCH
- HITS-CLIP yields genome-wide insights into brain alternative RNA processing
- (2008) Donny D. Licatalosi et al. NATURE
- Mapping and quantifying mammalian transcriptomes by RNA-Seq
- (2008) Ali Mortazavi et al. NATURE METHODS
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect
- (2008) Kumiko Ui-Tei et al. NUCLEIC ACIDS RESEARCH
- Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
- (2008) M. Frank-Kamenetsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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