Article
Multidisciplinary Sciences
Long Xu, Wei Xiong, Minghao Zhou, Lei Chen
Summary: This paper proposes a method for dynamic traffic monitoring in industrial communication networks using a dynamic fluid-flow model. The method utilizes a continuous terminal sliding-mode observer and a full-order sliding-mode mechanism for real-time estimation of traffic anomalies. The effectiveness of the method is demonstrated through experiments.
Article
Engineering, Electrical & Electronic
Saleh Mobayen, Khalid A. Alattas, Wudhichai Assawinchaichote
Summary: The paper proposes an improved finite time sliding mode controller scheme for robotic manipulators with external disturbances. By introducing a new Lyapunov candidate functional containing an absolute function based on a fractional power of the switching surface, the designed control law is continuous and smooth, eliminating the chattering phenomenon typically associated with conventional sliding mode controllers. The control technique designed using Lyapunov stability theory ensures the presence of sliding mode around the switching surface in finite time, while adaptive tuning controllers are used to approximate unknown bounds of external disturbances, improving precision and robustness in tracking control of nonlinear systems.
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS
(2021)
Article
Engineering, Multidisciplinary
Xin Jin, Zhengxin Wang, Xiaojie Chen, Yang Cao, Guo-Ping Jiang
Summary: This paper focuses on global almost sure exponential synchronization of a specific class of multiplex networks, providing sufficient criteria for achieving synchronization and further investigating the effects of switchings and impulses. Theoretical relationships and practical methods are established to reduce conservativeness and solve the influence of switchings and impulses. This study also verifies the theoretical results through numerical examples.
IEEE TRANSACTIONS ON NETWORK SCIENCE AND ENGINEERING
(2021)
Article
Optics
Tom Lenkiewicz Abudi, Mark Douvidzon, Baheej Bathish, Tal Carmon
Summary: The study introduces a hybrid resonator composed of a dielectric disk and a continuous membrane, where the membrane can move continuously in two dimensions and interact with the disk. Experimental results demonstrate that parallel movement of the membrane can adjust the optical resonance frequency, and the membrane's motion could have significant impact on sustainable sensors and carrying quantum dots.
Article
Automation & Control Systems
Yuanlong Xie, Xiaolong Zhang, Shiqi Zheng, Choon Ki Ahn, Shuting Wang
Summary: A novel control scheme for mobile robots is proposed to achieve robust tracking control through asynchronous adaptive mode allocation. By optimizing continuous control inputs for each subsystem and utilizing a supervisory criterion for autonomous mode switching, the system behaviors are managed asynchronously to enhance performance.
IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS
(2022)
Article
Computer Science, Artificial Intelligence
Zeinab Echreshavi, Mohsen Farbood, Mokhtar Shasadeghi
Summary: This article investigates the design of an event-triggered-based integral sliding mode control for a class of TSFM-based nonlinear systems, proposing a more reasonable ETISMC law, ensuring stability of the closed-loop system, and formulating new sufficient conditions in terms of offline linear matrix inequalities.
IEEE TRANSACTIONS ON FUZZY SYSTEMS
(2022)
Article
Mathematics, Applied
Yinghua Wang, Bao-Shan Wang, Leevan Ling, Wai Sun Don
Summary: This paper proposes a time-continuous embedding method for solving nonlinear hyperbolic conservation laws with discontinuous solutions in two and three-dimensional spaces. The method improves upon traditional embedding methods in terms of accuracy and efficiency, and shows excellent performance in solving complex problems.
JOURNAL OF SCIENTIFIC COMPUTING
(2022)
Article
Computer Science, Information Systems
Yanmin Wang, Weiqi Zhang, Chen Xue
Summary: A novel adaptive continuous sliding mode control approach is proposed in this paper, using the twisting algorithm to ensure control continuity and adaptive time-varying control gain to eliminate low precision issues. The controller magnitude can be reduced to a minimal admissible level to ensure system stability and robustness.
Article
Engineering, Electrical & Electronic
Jianxiong Li, Xinjian Liu, Miao Xu, Yiming Fang
Summary: In this paper, a general continuous higher-order sliding mode control algorithm is proposed for a class of n-order systems with Lipschitz disturbance. The algorithm only requires limited information of the output and its derivatives and can compensate the disturbance exactly, achieving finite-time convergence. Simulation results validate the effectiveness of the proposed method.
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS II-EXPRESS BRIEFS
(2022)
Article
Automation & Control Systems
Richard Seeber, Jaime A. Moreno
Summary: This paper proposes a technique to extend a nominal state-feedback control law by integral terms to suppress non-vanishing perturbations. The new approach maintains nominal performance and includes the super-twisting algorithm as a special case. Simulations demonstrate intuitive tuning and performance-preserving effects even in perturbed cases.
INTERNATIONAL JOURNAL OF ROBUST AND NONLINEAR CONTROL
(2021)
Article
Automation & Control Systems
Yingchun Wang, Baopeng Zhu, Huaguang Zhang, Wei Xing Zheng
Summary: This paper presents a finite-time adaptive integral sliding mode control method based on a functional observer, with an adaptive compensator designed to handle the effect of unknown nonlinear function for ensuring boundedness in a predefined finite time. Some sufficient conditions are proposed to guarantee finite-time boundedness with H-infinity performance, and the flexibility and conservatism of the designed controller are improved by introducing more degrees of freedom in the functional observer. The validity of the proposed method is demonstrated through a simulation example.
Article
Engineering, Aerospace
Zeyu Guo, Zuo Wang, Shihong Ding, Shihua Li, Xiangyu Wang
Summary: In this article, a robust continuous controller is investigated to solve the global finite-time attitude stabilization problem of rigid spacecraft system subject to multiple disturbances. The system order is increased by derivation and the derivative of the actual torque is regarded as the virtual control law to be designed. A super-twisting differentiator is constructed to provide finite-time angular acceleration estimations. Based on the estimated angular accelerations, a discontinuous set stabilization control law is designed as the virtual controller. Rigorous proof and stability analysis are presented based on Lyapunov analysis. Compared with existing approaches, the proposed continuous control scheme guarantees the finite-time set stability of the closed-loop system, even in the presence of derivative-bounded disturbances. Simulation studies demonstrate the strong disturbance rejection ability, fast convergence rate, and high steady-state precision of the proposed controller.
IEEE TRANSACTIONS ON AEROSPACE AND ELECTRONIC SYSTEMS
(2023)
Article
Automation & Control Systems
Bailing Tian, Zhiyu Li, Qun Zong
Summary: This article proposes a multivariable finite-time control algorithm for double integrator systems with matched disturbances. The algorithm ensures the finite-time stability of the closed-loop system and uniformly bounded control signal. The convergence criteria are derived using Lyapunov-based techniques, and the upper bound of the control signal can be calculated based on the obtained criteria. The effectiveness of the algorithm is confirmed through numerical simulations.
IEEE TRANSACTIONS ON AUTOMATIC CONTROL
(2022)
Article
Automation & Control Systems
Lu Chen, Jian-an Fang
Summary: The main purpose of this paper is to design a continuous sliding mode control, which addresses the stability problem of fractional-order nonlinear systems considering both matched and unmatched uncertainties, as well as unknown control gains. Three different sliding mode controllers are proposed to mitigate the chattering problem, incorporating an adaptive fractional-order filter. A control function composed of a novel SMC method and backstepping control is introduced to handle the unmatched uncertainty. The analysis results of this paper are theoretically proved using fractional-order Lyapunov technology and finite-time control strategy. Finally, the effectiveness and feasibility of the proposed chattering-free sliding mode control are demonstrated through its application to the control of a fractional-order horizontal platform system.
INTERNATIONAL JOURNAL OF CONTROL AUTOMATION AND SYSTEMS
(2022)
Article
Automation & Control Systems
Lijing Dong, Daniel W. C. Ho, Sheng-Li Du
Summary: The paper investigates the coordination tracking problem of multiagent systems for threat defense in a monitored area. A modified nonsingular terminal sliding mode controller is proposed for the agents, along with a novel continuous function to eliminate singularity and estimate finite tracking time. A generalized Voronoi diagram considering the velocity of second-order agents and targets is presented based on the estimated time, with coordination strategies triggered by node failures or target entering new cells.
IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS
(2021)
Review
Biochemistry & Molecular Biology
Michael H. Wissing, Yannick Bruggemann, Eike Steinmann, Daniel Todt
Summary: HEV is a long-neglected RNA virus and the major causative agent of acute viral hepatitis worldwide. Understanding the interactions between HEV and host cells can provide important insights for studying the viral life cycle and help in designing new therapeutic strategies.
TRENDS IN MICROBIOLOGY
(2021)
Article
Developmental Biology
Angel Stanoev, Christian Schroeter, Aneta Koseska
Summary: During mammalian development and homeostasis, cells transition from a multilineage primed state to differentiated cell types marked by specific genetic markers. This study proposes a new dynamical mechanism where cell types emerge collectively maintained by cell-cell communication, triggering differentiation as the population grows. The inhomogeneous state allows for robust proportioning and reliable recovery of differentiated cell types following perturbations.
Article
Gastroenterology & Hepatology
Patrick Behrendt, Martina Friesland, Jan-Erik Wissmann, Volker Kinast, Yannick Stahl, Dimas Praditya, Lucas Hueffner, Pia Maria Noerenberg, Birgit Bremer, Benjamin Maasoumy, Jochen Steinmann, Britta Becker, Dajana Paulmann, Florian H. H. Brill, Joerg Steinmann, Rainer G. Ulrich, Yannick Brueggemann, Heiner Wedemeyer, Daniel Todt, Eike Steinmann
Summary: HEV demonstrated resistance to alcohols and alcohol-based disinfectants, with the addition of phosphoric acid being essential for virucidal activity. These findings are crucial for guiding improved hygiene measures to prevent HEV transmission.
JOURNAL OF HEPATOLOGY
(2022)
Article
Public, Environmental & Occupational Health
T. L. Meister, D. Todt, Y. Bruggemann, J. Steinmann, S. Banava, F. H. H. Brill, S. Pfaender, E. Steinmann
Summary: The highest viral loads of SARS-CoV-2 can be detected in the oral cavity, and nasal and oral sprays have the potential to reduce transmission. Two sprays, one nasal spray with sodium hypochlorite and one oral spray with essential oils, effectively reduced viral titres. These sprays are more convenient for elderly individuals or those unable to rinse or gargle.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Cell Biology
Thomas Burkard, Nora Proske, Kathrin Resner, Laura Collignon, Leonard Knegendorf, Martina Friesland, Lieven Verhoye, Ibrahim M. Sayed, Yannick Bruggemann, Maximilian K. Nocke, Patrick Behrendt, Heiner Wedemeyer, Philip Meuleman, Daniel Todt, Eike Steinmann
Summary: This study found direct interference between HCV and HEV in human hepatocytes and humanized mice. The protease activity of HCV was found to be linked to this interference. In vivo experiments confirmed that super-infection reduced the replication of both viruses in individual mice.
Article
Pharmacology & Pharmacy
Dimas F. Praditya, Mara Kloehn, Yannick Brueggemann, Lauren E. Brown, John A. Porco, Wenhan Zhang, Volker Kinast, Andreas Kirschning, Florian W. R. Vondran, Daniel Todt, Eike Steinmann
Summary: This study evaluated the antiviral properties of 205 synthetic rocaglate derivatives against HEV. At least 11 compounds showed inhibitory activities against HEV, with three amidino-rocaglates exhibiting strong antiviral activity against different genotypes of HEV. These compounds also showed better tolerance in normal liver cells and displayed additive effects when combined with ribavirin and interferon-α.
ANTIVIRAL RESEARCH
(2022)
Editorial Material
Cell Biology
Yannick Brueggemann, Annika Kratzel, Lea Almeida, Jenna N. Kelly, Volker Thiel, Stephanie Pfaender
Summary: A recent study identified host dependency factors, including immunophilins FKBP8, TMEM41B, and MINAR1, which regulate the macroautophagy/autophagy pathway and play crucial roles in the lifecycle of coronaviruses such as SARS-CoV, MERS-CoV, and SARS-CoV-2. These factors could potentially serve as therapeutic targets for the treatment of these emerging coronaviruses.
Editorial Material
Gastroenterology & Hepatology
Yannick Brueggemann, Mara Kloehn, Daniel Todt
JOURNAL OF HEPATOLOGY
(2022)
Article
Microbiology
Toni Luise Meister, Luis G. Arroyo, Rachel Shanahan, Maria A. Papapetrou, Birthe Reinecke, Yannick Brueggemann, Daniel Todt, Alexander Stang, Murray Hazlett, John D. Baird, Eike Steinmann
Summary: Theiler's disease (TD) is a common cause of acute hepatic failure in adult horses, with recent findings suggesting that EqPV-H may be the cause. A study monitored close-contact mares and foals following the death of an EqPV-H positive mare with TD, revealing that foals had higher EqPV-H viral loads than the mares.
VETERINARY MICROBIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
J. E. Wissmann, Y. Bruggemann, D. Todt, J. Steinmann, E. Steinmann
Summary: A carrier assay based on HEV was established to evaluate its surface stability and the virucidal activity of nine surface disinfectants. The results showed that alcohol-based disinfectants were insufficient to eliminate HEV infectivity, while disinfectants based on aldehyde, peracetic acid, oxygen, and/or quaternary ammonium inactivated HEV. These findings have important implications for the recommendation of evidence-based hygiene guidelines to reduce HEV transmission.
JOURNAL OF HOSPITAL INFECTION
(2023)
Article
Gastroenterology & Hepatology
Jil A. Schrader, Thomas L. Burkard, Yannick Brueggemann, Andre Goemer, Toni L. Meister, Rebecca M. Fu, Ann-Kathrin Mehnert, Viet L. Dao Thi, Patrick Behrendt, David Durantel, Ruth Broering, Florian W. R. Vondran, Daniel Todt, Volker Kinast, Eike Steinmann
Summary: This study identified the EGF receptor (EGFR) as a novel host factor for HEV and revealed the significance of EGFR for the HEV entry process. It was found that EGFR itself and its ligand-binding domain, rather than its signaling function, is responsible for the proviral effect. These findings provide new insights into the life cycle of HEV and identify EGFR as a potential target for future antiviral strategies against HEV.
Article
Immunology
Toni Luise Meister, Yannick Brueggemann, Daniel Todt, Ronny Tao, Lisa Mueller, Jochen Steinmann, Joerg Steinmann, Joerg Timm, Ingo Drexler, Eike Steinmann
Summary: The spread of nonzoonotic monkeypox virus (MPXV) infections requires a reevaluation of hygiene measures. Evaluation of MPXV stability at different temperatures and interfering substances showed increased persistence at lower temperatures. MPXV can be efficiently inactivated by alcohol- and aldehyde-based surface disinfectants.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Immunology
Toni L. Meister, Ronny Tao, Yannick Bruggemann, Daniel Todt, Joerg Steinmann, Joerg Timm, Ingo Drexler, Eike Steinmann
Summary: Given the increasing cases of nonzoonotic human monkeypox virus (MPXV) infections, it is necessary to reevaluate inactivation strategies. This study demonstrates the effectiveness of 2 alcohol-based hand rub solutions recommended by the World Health Organization in inactivating MPXV. Compared to other (re)emerging enveloped viruses, MPXV shows the highest stability. These findings emphasize the importance of using alcohol-based disinfectants.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Biochemistry & Molecular Biology
Angel Stanoev, Aneta Koseska
Summary: This paper reviews the dynamical mechanisms of mammalian development and discusses the emergent properties of cell populations in terms of differentiation timing, cell-type proportions, and recovery from perturbations. It argues that studying developmental systems through transitions in collective system states is necessary to describe experimental features, and proposes a novel analytical method to deduce the relationship between single-cell dynamics and collective, symmetry-broken states in cellular populations.
CURRENT OPINION IN SYSTEMS BIOLOGY
(2022)
Article
Biochemical Research Methods
Toni Luise Meister, Yannick Brueggemann, Barbora Tamele, John Howes, Eike Steinmann, Daniel Todt
Summary: This article presents a protocol for investigating the direct transfer of infectious agents from fomites to humans via naked fingertips. The protocol is suitable for high biosafety level pathogens, such as SARS-CoV-2, and allows for quantitative measurement of transfer efficiency and risk assessment.
