Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections
出版年份 2018 全文链接
标题
Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume -, Issue -, Pages 201809422
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-09-25
DOI
10.1073/pnas.1809422115
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structural insights into the mechanism of inhibition of AHAS by herbicides
- (2018) Thierry Lonhienne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides
- (2017) Mario Daniel Garcia et al. FEBS Journal
- The Role of a FAD Cofactor in the Regulation of Acetohydroxyacid Synthase by Redox Signaling Molecules
- (2017) Thierry Lonhienne et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures
- (2017) Harry C Jubb et al. JOURNAL OF MOLECULAR BIOLOGY
- Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families
- (2017) Mario D. Garcia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antifungal Therapy for Systemic Mycosis and the Nanobiotechnology Era: Improving Efficacy, Biodistribution and Toxicity
- (2017) Ana C. O. Souza et al. Frontiers in Microbiology
- The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements
- (2017) Thierry Lonhienne et al. PLoS One
- Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase
- (2016) Thierry Lonhienne et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Aspergillus fumigatus Intrinsic Fluconazole Resistance Is Due to the Naturally Occurring T301I Substitution in Cyp51Ap
- (2016) Florencia Leonardelli et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Sodium ascorbate kills Candida albicans in vitro via iron-catalyzed Fenton reaction: importance of oxygenation and metabolism
- (2016) Pinar Avci et al. Future Microbiology
- Antifungal Agents
- (2016) Jeniel E. Nett et al. INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
- How to bolster the antifungal pipeline
- (2015) D. W. Denning et al. SCIENCE
- How good are my data and what is the resolution?
- (2013) Philip R. Evans et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Identification and Evaluation of Novel Acetolactate Synthase Inhibitors as Antifungal Agents
- (2013) Daryl L. Richie et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The Antifungal Eugenol Perturbs Dual Aromatic and Branched-Chain Amino Acid Permeases in the Cytoplasmic Membrane of Yeast
- (2013) Emad Darvishi et al. PLoS One
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Growth Inhibition of Pathogenic Bacteria by Sulfonylurea Herbicides
- (2012) Jason F. Kreisberg et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Sulfonylureas Have Antifungal Activity and Are Potent Inhibitors of Candida albicans Acetohydroxyacid Synthase
- (2012) Yu-Ting Lee et al. JOURNAL OF MEDICINAL CHEMISTRY
- Hidden Killers: Human Fungal Infections
- (2012) G. D. Brown et al. Science Translational Medicine
- Presenting your structures: theCCP4mgmolecular-graphics software
- (2011) S. McNicholas et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- A Clinical Isolate of Candida albicans with Mutations in ERG11 (Encoding Sterol 14 -Demethylase) and ERG5 (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B
- (2010) C. M. Martel et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection
- (2010) D. M. MacCallum et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Molecular Mechanisms of Resistance to 5-Fluorocytosine in Laboratory Mutants of Candida glabrata
- (2010) Patrick Vandeputte et al. MYCOPATHOLOGIA
- Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2 ) mutants is influenced by the carbon source and rapamycin
- (2009) J. M. Kingsbury et al. MICROBIOLOGY-SGM
- Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8
- (2009) Elmar Krieger et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Thiamin Diphosphate Catalysis: Enzymic and Nonenzymic Covalent Intermediates
- (2008) Ronald Kluger et al. CHEMICAL REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation