Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair

Loss of heterozygosity preferentially occurs in early replicating regions in cancer genomes

(2013) B. S. Pedersen et al.   NUCLEIC ACIDS RESEARCH

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer

(2012) V Abkevich et al.   BRITISH JOURNAL OF CANCER

The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1

(2012) Audun Hanssen-Bauer et al.   DNA REPAIR

Acquired Uniparental Disomy in Myeloproliferative Neoplasms

(2012) Joannah Score et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

(2012) Cherie L. Ramirez et al.   NUCLEIC ACIDS RESEARCH

Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics

(2012) J. J. Foti et al.   SCIENCE

Disconnecting XRCC1 and DNA ligase III

(2011) Sachin Katyal et al.   CELL CYCLE

Pathogenesis and Consequences of Uniparental Disomy in Cancer

(2011) H. Makishima et al.   CLINICAL CANCER RESEARCH

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

(2011) Deniz Simsek et al.   NATURE

DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair

(2011) Yankun Gao et al.   NATURE

Tracking genome engineering outcome at individual DNA breakpoints

(2011) Michael T Certo et al.   NATURE METHODS

High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

(2011) Fuqiang Chen et al.   NATURE METHODS

Concerted nicking of donor and chromosomal acceptor DNA promotes homology-directed gene targeting in human cells

(2011) Manuel A. F. V. Gonçalves et al.   NUCLEIC ACIDS RESEARCH

DNA Nicks Promote Efficient and Safe Targeted Gene Correction

(2011) Luther Davis et al.   PLoS One

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

The Tumor Microenvironment and DNA Repair

(2010) Thomas J. Klein et al.   SEMINARS IN RADIATION ONCOLOGY

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

(2009) A. McConnell Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in Chemical Carcinogenesis: A Historical Review and Prospective

(2008) L. A. Loeb et al.   CANCER RESEARCH

Single-strand break repair and genetic disease

(2008) Keith W. Caldecott   NATURE REVIEWS GENETICS

Transcription-coupled DNA repair: two decades of progress and surprises

(2008) Philip C. Hanawalt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics