ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord

(2014) Mark D. Borromeo et al.   DEVELOPMENT

PTEN Is a Potent Suppressor of Small Cell Lung Cancer

(2014) Min Cui et al.   MOLECULAR CANCER RESEARCH

Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations

(2013) Mitsuo Sato et al.   MOLECULAR CANCER RESEARCH

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

(2013) Andrew J Souers et al.   NATURE MEDICINE

ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation

(2013) F Kosari et al.   ONCOGENE

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM

(2013) J. K. Osborne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase II Study of Single-Agent Navitoclax (ABT-263) and Biomarker Correlates in Patients with Relapsed Small Cell Lung Cancer

(2012) C. M. Rudin et al.   CLINICAL CANCER RESEARCH

An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

(2012) L. A. Byers et al.   CLINICAL CANCER RESEARCH

Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis

(2011) X. Tang et al.   CLINICAL CANCER RESEARCH

Insights into the achaete-scute homolog-1 gene (hASH1) in normal and neoplastic human lung

(2011) Makoto Miki et al.   LUNG CANCER

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Small Cell Lung Cancer: Past, Present, and Future

(2010) Estelamari Rodriguez et al.   Current Oncology Reports

Achaete-Scute Complex Homologue 1 Regulates Tumor-Initiating Capacity in Human Small Cell Lung Cancer

(2009) T. Jiang et al.   CANCER RESEARCH

Relapse-Related Molecular Signature in Lung Adenocarcinomas Identifies Patients With Dismal Prognosis

(2009) Shuta Tomida et al.   JOURNAL OF CLINICAL ONCOLOGY

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors

(2009) Shimakage   ONCOLOGY REPORTS

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Therapeutic Efficacy of ABT-737, a Selective Inhibitor of BCL-2, in Small Cell Lung Cancer

(2008) C. L. Hann et al.   CANCER RESEARCH

Activity of the Bcl-2 Family Inhibitor ABT-263 in a Panel of Small Cell Lung Cancer Xenograft Models

(2008) A. R. Shoemaker et al.   CLINICAL CANCER RESEARCH

Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

(2008) Kerby Shedden et al.   NATURE MEDICINE

Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer

(2008) K A Kwei et al.   ONCOGENE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY