标题
Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 33, Pages 12085-12090
出版商
Proceedings of the National Academy of Sciences
发表日期
2014-08-05
DOI
10.1073/pnas.1412504111
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Opposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance
- (2014) D. Oling et al. EMBO JOURNAL
- Polyglutamine-Rich Suppressors of Huntingtin Toxicity Act Upstream of Hsp70 and Sti1 in Spatial Quality Control of Amyloid-Like Proteins
- (2014) Katie J. Wolfe et al. PLoS One
- Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners
- (2013) Spyros Petrakis et al. BIOESSAYS
- PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone
- (2013) Sae-Hun Park et al. CELL
- The Hsp70/90 cochaperone, Sti1, suppresses proteotoxicity by regulating spatial quality control of amyloid-like proteins
- (2013) Katie J. Wolfe et al. MOLECULAR BIOLOGY OF THE CELL
- Glutathione peroxidase activity is neuroprotective in models of Huntington's disease
- (2013) Robert P Mason et al. NATURE GENETICS
- Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
- (2013) K. Sathasivam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blessings in disguise: biological benefits of prion-like mechanisms
- (2013) Gregory A. Newby et al. TRENDS IN CELL BIOLOGY
- easyFRAP: an interactive, easy-to-use tool for qualitative and quantitative analysis of FRAP data
- (2012) Maria Anna Rapsomaniki et al. BIOINFORMATICS
- The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
- (2012) Oliver D. King et al. BRAIN RESEARCH
- Amyloid-Mediated Sequestration of Essential Proteins Contributes to Mutant Huntingtin Toxicity in Yeast
- (2012) Natalia V. Kochneva-Pervukhova et al. PLoS One
- Identification of Human Proteins That Modify Misfolding and Proteotoxicity of Pathogenic Ataxin-1
- (2012) Spyros Petrakis et al. PLoS Genetics
- Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast
- (2012) He Gong et al. PLoS Genetics
- Macromolecular and small-molecule modulation of intracellular Aβ42aggregation and associated toxicity
- (2011) Sohini Chakrabortee et al. BIOCHEMICAL JOURNAL
- Protein aggregates in Huntington's disease
- (2011) Montserrat Arrasate et al. EXPERIMENTAL NEUROLOGY
- Slow Amyloid Nucleation via α-Helix-Rich Oligomeric Intermediates in Short Polyglutamine-Containing Huntingtin Fragments
- (2011) Murali Jayaraman et al. JOURNAL OF MOLECULAR BIOLOGY
- Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins
- (2011) Randal Halfmann et al. MOLECULAR CELL
- Identifying polyglutamine protein species in situ that best predict neurodegeneration
- (2011) Jason Miller et al. Nature Chemical Biology
- A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network
- (2011) M. Catarina Silva et al. PLoS Genetics
- Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes
- (2011) Anita L. Manogaran et al. PLoS Genetics
- Essential Role of Coiled Coils for Aggregation and Activity of Q/N-Rich Prions and PolyQ Proteins
- (2010) Ferdinando Fiumara et al. CELL
- A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins
- (2009) Simon Alberti et al. CELL
- Secondary Structure of Huntingtin Amino-Terminal Region
- (2009) Mee Whi Kim et al. STRUCTURE
- Phosphorylation of Profilin by ROCK1 Regulates Polyglutamine Aggregation
- (2008) J. Shao et al. MOLECULAR AND CELLULAR BIOLOGY
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- Polyglutamine Genes Interact to Modulate the Severity and Progression of Neurodegeneration in Drosophila
- (2008) Derek Lessing et al. PLOS BIOLOGY
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