Tumor-specific IL-9–producing CD8+Tc9 cells are superior effector than type-I cytotoxic Tc1 cells for adoptive immunotherapy of cancers

T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment

(2013) Joel Crespo et al.   CURRENT OPINION IN IMMUNOLOGY

Th9 cells: differentiation and disease

(2013) Mark H. Kaplan   IMMUNOLOGICAL REVIEWS

Adoptive Transfer of Tc1 or Tc17 Cells Elicits Antitumor Immunity against Established Melanoma through Distinct Mechanisms

(2013) Y. Yu et al.   JOURNAL OF IMMUNOLOGY

Utilizing TH9 cells as a novel therapeutic strategy for malignancies

(2013) Yong Lu et al.   OncoImmunology

Tc9 cells, a new subset of CD8+T cells, support Th2-mediated airway inflammation

(2012) Alexander Visekruna et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Th9 cells promote antitumor immune responses in vivo

(2012) Yong Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-  Converts Apoptotic Stimuli into the Signal for Th9 Differentiation

(2012) M. Takami et al.   JOURNAL OF IMMUNOLOGY

Robust tumor immunity to melanoma mediated by interleukin-9–producing T cells

(2012) Rahul Purwar et al.   NATURE MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy

(2011) S. A. Rosenberg et al.   CLINICAL CANCER RESEARCH

Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients

(2011) Lukas Baitsch et al.   JOURNAL OF CLINICAL INVESTIGATION

A Brief History of IL-9

(2011) R. Goswami et al.   JOURNAL OF IMMUNOLOGY

Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy

(2010) C. S. Hinrichs et al.   BLOOD

Adoptive Transfer of Tumor-Specific Tc17 Effector T Cells Controls the Growth of B16 Melanoma in Mice

(2010) M. d. l. L. Garcia-Hernandez et al.   JOURNAL OF IMMUNOLOGY

TGF-β1 Induces Preferential Rapid Expansion and Persistence of Tumor Antigen-specific CD8+ T Cells for Adoptive Immunotherapy

(2010) Shujuan Liu et al.   JOURNAL OF IMMUNOTHERAPY

Type 17 CD8+ T cells display enhanced antitumor immunity

(2009) C. S. Hinrichs et al.   BLOOD

Adoptive cell therapy for the treatment of patients with metastatic melanoma

(2009) Steven A Rosenberg et al.   CURRENT OPINION IN IMMUNOLOGY

Regulating functional cell fates in CD8 T cells

(2009) Protul A. Shrikant et al.   IMMUNOLOGIC RESEARCH

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

(2009) Lin Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cyclophosphamide Chemotherapy Sensitizes Tumor Cells to TRAIL-Dependent CD8 T Cell-Mediated Immune Attack Resulting in Suppression of Tumor Growth

(2009) Robbert G. van der Most et al.   PLoS One

Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity

(2009) C. S. Hinrichs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

(2008) C. S. Hinrichs et al.   BLOOD