Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297
出版年份 2014 全文链接
标题
Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 29, Pages 10755-10760
出版商
Proceedings of the National Academy of Sciences
发表日期
2014-07-08
DOI
10.1073/pnas.1405190111
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- ML297 (VU0456810), the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice
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- Repeated Cocaine Weakens GABAB-Girk Signaling in Layer 5/6 Pyramidal Neurons in the Prelimbic Cortex
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- Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels
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- New insights into the therapeutic potential of Girk channels
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- Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity
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- (2012) K. Xie et al. Science Signaling
- Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q
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- Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium
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- The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers
- (2009) Bettye Hollins et al. CELLULAR SIGNALLING
- A discrete alcohol pocket involved in GIRK channel activation
- (2009) Prafulla Aryal et al. NATURE NEUROSCIENCE
- Behavioral characterization of mice lacking GIRK/Kir3 channel subunits
- (2008) M. Pravetoni et al. GENES BRAIN AND BEHAVIOR
- Voltage-sensing phosphatase: actions and potentials
- (2008) Yasushi Okamura et al. JOURNAL OF PHYSIOLOGY-LONDON
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